Clinical Trials Directory

Trials / Terminated

TerminatedNCT00031473

Ribavirin to Prevent RSV Pneumonia in Bone Marrow Transplant Patients

A Randomized Phase III Study to Evaluate the Safety and Efficacy of Ribavirin Inhaled Solution in Preventing Progression of Upper Respiratory Tract Respiratory Syncytial Virus Infection to RSV Pneumonia in Blood and Bone Marrow Transplant (BMT) Recipient

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
90 (planned)
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID) · NIH
Sex
All
Age
5 Years – 60 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to test the safety and effectiveness of ribavirin, administered as an aerosol, in preventing progression of upper respiratory tract RSV infection to RSV pneumonia in bone marrow and peripheral blood transplant recipients.

Detailed description

The study enrolls 90 transplant recipients with positive nasal/throat culture specimens for Respiratory Syncytial Virus (RSV) infection. Patients are randomized into one of two groups: investigational treatment or standard treatment.

Conditions

Interventions

TypeNameDescription
DRUGVirazole (Ribavirin) Inhalation Solution

Timeline

Start date
1997-11-01
Completion
2003-03-01
First posted
2002-03-07
Last updated
2010-08-27

Locations

11 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00031473. Inclusion in this directory is not an endorsement.