Trials / Completed
CompletedNCT00015626
A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 300 (planned)
- Sponsor
- National Center for Research Resources (NCRR) · NIH
- Sex
- All
- Age
- 5 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this study is to aggressively treat insulin resistance and its clinical manifestations when they first appear in childhood, and to prevent the subsequent progression towards impaired glucose tolerance and type-2 diabetes. In the process of this clinical trial, we will learn more about the early manifestations of insulin resistance, its treatment, and its relationship to obesity and type-2 diabetes through parallel in-vivo and in-vitro studies.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Metformin | |
| PROCEDURE | skin biopsy | |
| BEHAVIORAL | diet and exercise | |
| DRUG | pioglitazone | |
| DRUG | rosiglitazone |
Timeline
- First posted
- 2001-04-26
- Last updated
- 2005-06-24
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00015626. Inclusion in this directory is not an endorsement.