Trials / Completed
CompletedNCT00007033
Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 25 (planned)
- Sponsor
- National Center for Research Resources (NCRR) · NIH
- Sex
- All
- Age
- 3 Years – 18 Years
- Healthy volunteers
- Not accepted
Summary
OBJECTIVES: I. Determine the role of magnesium deficiency in the pathogenesis of decreased serum vitamin D and reduced bone density in children with chronic cholestatic liver disease.
Detailed description
PROTOCOL OUTLINE: Patients receive magnesium sulfate IV over 1 hour on day 3. Patients then receive oral magnesium gluconate supplementation daily. Treatment with magnesium sulfate repeats once at 3-6 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | magnesium gluconate | |
| DRUG | magnesium sulfate |
Timeline
- Start date
- 2000-10-01
- First posted
- 2000-12-07
- Last updated
- 2009-01-22
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00007033. Inclusion in this directory is not an endorsement.