NCT00006203

Naltrexone, Craving, and Drinking

Naltrexone, Craving, and Drinking: Ecological Assessment

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: Brown University · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This 5-week study will examine the effects of naltrexone on alcohol craving, drinking rates, and reaction to drinking-related triggers, or cues, in participants' everyday environment and in laboratory sessions. Participants will monitor and record their daily desires to drink, environmental circumstances in which urges occur, and drinking behavior using a palm top computer. Participants will receive naltrexone or a placebo. One week after receiving medication, all participants will be asked to respond to alcohol-related cues that may or may not arouse the desire to drink.

Conditions

• Alcoholism

Interventions

Type	Name	Description
DRUG	Naltrexone 50 Mg	Daily 50 mg for 3 weeks
DRUG	Placebo	Daily doses of placebo for 3 weeks

Timeline

• Completion: 2005-05-01
• First posted: 2000-09-12
• Last updated: 2025-06-13

Locations

1 site across 1 country: United States