Trials / Completed
CompletedNCT00005668
A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 96 (planned)
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID) · NIH
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To compare the safety and effectiveness of itraconazole oral solution to placebo in the treatment of a pulmonary aspergilloma. Aspergilloma is a "fungal ball" in the lungs caused by Aspergillus. The infection can spread from the lungs through the blood to other organs. Aspergilloma can be life-threatening; therefore, an effective treatment is needed.
Detailed description
Patients are randomly selected to receive itraconazole oral solution by mouth or the inactive placebo (oral cyclodextrin solution) twice daily for 12 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Itraconazole oral solution |
Timeline
- Completion
- 2005-11-01
- First posted
- 2001-08-31
- Last updated
- 2010-08-27
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00005668. Inclusion in this directory is not an endorsement.