NCT00001620

Screening for Hematology Branch Protocols

Screening Protocol for Subjects Being Evaluated for National Heart, Lung and Blood Institute (NHLBI) Protocols

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: National Heart, Lung, and Blood Institute (NHLBI) · NIH
• Sex: All
• Age: 2 Years – 100 Years
• Healthy volunteers: Accepted

Summary

This study allows the evaluation of subjects in order to determine their ability to safely participate in other active research studies. After subjects complete the screening process, they will be offered the opportunity to participate in an active research study, or if no appropriate studies are available information and recommendations will be provided for other treatment options....

Detailed description

This protocol is designed for screening of subjects before a decision can be made as to their eligibility for one of the active National Heart, Lung, and Blood Institute (NHLBI) research protocols. Its purpose is to allow detailed investigation into the hematologic or oncologic problems of these subjects, and the status of other organ systems that would determine their ability to safely tolerate specific aspects of active research protocols. It allows investigation as to whether a donor is HLA matched, fit to receive G-CSF, and fit to undergo apheresis and therefore eligible to participate as a donor on a bone marrow transplant protocol. It also allows the investigation as to whether subjects are eligible for participation as normal volunteer based on protocol eligibility criteria that requires generally good health status by history or physical exam findings, or laboratory assessments. After completion of this screening process, the subject will either be offered a chance to participate in an active research protocol, or if no appropriate protocol is identified, subjects with hematologic or oncologic disease will have recommendations for other treatment options relayed to the primary or referring physician. Primary objective is to determine subject eligibility for participation on NHLBI protocols. Primary endpoint is the results of clinical, imaging and laboratory assessments.

Conditions

• Hematologic Disease and Disorders
• Donors
• Healthy Volunteer

Timeline

• Start date: 1996-12-31
• First posted: 1999-11-04
• Last updated: 2026-04-08

Locations

1 site across 1 country: United States