NCT00000259

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 21 Years – 39 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and psychomotor performance.

Conditions

• Opioid-Related Disorders
• Substance-Related Disorders

Interventions

Type	Name	Description
DRUG	15 % Nitrous oxide
DRUG	0.3 % Sevoflurane
DRUG	30% Nitrous oxide
DRUG	0.6% Sevoflurane
OTHER	Placebo

Timeline

• Start date: 1996-08-01
• Primary completion: 1997-11-01
• Completion: 1997-11-01
• First posted: 1999-09-21
• Last updated: 2015-05-28

Locations

1 site across 1 country: United States