NCT00000254

Isoflurane at Subanesthetic Concentrations - 6

Isoflurane at Subanesthetic Concentrations

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: Male
• Age: 21 Years – 34 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To test the hypothesis that isoflurane at subanesthetic concentrations does not reduce cold-water immersion pain in healthy volunteers.

Conditions

• Opioid-Related Disorders
• Substance-Related Disorders

Interventions

Type	Name	Description
DRUG	40% Nitrous oxide	Used as pain assay positive control
OTHER	Sham comparator	0% isoflurane in oxygen
DRUG	0.2% isoflurane
DRUG	0.4% isoflurane
DRUG	0.6% isoflurane

Timeline

• Start date: 1995-01-01
• Primary completion: 1995-09-01
• Completion: 1995-09-01
• First posted: 1999-09-21
• Last updated: 2015-05-28

Locations

1 site across 1 country: United States