NCT00000250

Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 21 Years – 32 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.

Conditions

• Opioid-Related Disorders
• Substance-Related Disorders

Interventions

Type	Name	Description
DRUG	0% N2O	Subjects will inhale 100% oxygen with no N2O for 25 min then immerse forearm in warm water and cold water
DRUG	40% N2O	Subjects will inhale 40% N2O then immerse forearm in warm water and cold water

Timeline

• Start date: 1993-12-01
• Primary completion: 1995-05-01
• Completion: 1995-05-01
• First posted: 1999-09-21
• Last updated: 2015-05-28

Locations

1 site across 1 country: United States