Trials / Completed
CompletedNCT00000177
Estrogen Hormone Protocol
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 120 (planned)
- Sponsor
- National Institute on Aging (NIA) · NIH
- Sex
- Female
- Age
- 60 Years
- Healthy volunteers
- Not accepted
Summary
Estrogen is a hormone that is dominant in the female reproductive system. In women, most estrogen is produced by the ovaries. Men produce estrogen by converting testosterone into estrogen. Because this hormone also has many beneficial effects on brain cells, it currently is being studied as a treatment for Alzheimer's disease. The enzyme that forms the neurotransmitter acetylcholine is promoted in the presence of estrogen. Several very small clinical studies have demonstrated improvement in cognitive function and mood measures in women with Alzheimer's disease who take estrogen.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Estrogen |
Timeline
- Start date
- 1995-10-01
- Primary completion
- 1999-01-01
- Completion
- 1999-01-01
- First posted
- 1999-11-01
- Last updated
- 2009-12-11
Locations
25 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00000177. Inclusion in this directory is not an endorsement.