Clinical Trials Directory

Trials / Sponsors / Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Academic / Other · 56 registered clinical trials14 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingStudy of Treosulfan-Based Conditioning for HSCT in Nijmegen Breakage Syndrome
HSCT, Nijmegen Breakage Syndrome, Treosulfan Based Conditioning
Phase 22025-12-30
RecruitingChemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapse
Neuroblastoma (NB), Ganglioneuroblastoma
Phase 32025-11-19
RecruitingCo-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graf
Acute Myeloid Leukemia, Relapsed, Acute Lymphoblastic Leukemia, High Risk, Acute Myeloid Leukemia, High Risk
Phase 2 / Phase 32025-09-03
RecruitingThe Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia
AML (Acute Myelogenous Leukemia), Down Syndrome (DS)
Phase 32025-07-24
RecruitingFeasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic
Acute Myeloid Leukemia, Acute Lymphoblastic T-cell Leukemia, Mixed Phenotype Acute Leukemia
Phase 22025-05-09
Active Not RecruitingEmapalumab Efficacy in Children With Primary Hemophagocytic Lymphohistiocytosis
Primary Hemophagocytic Lymphohistiocytosis
2024-08-01
RecruitingPreventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Child
Biphenotypic Acute Leukemia, Acute Lymphoblastic Leukemia, Myeloblastic Leukemia
Phase 2 / Phase 32024-07-10
CompletedSuccessful Treatment of Netherton Syndrome With Combination of Secukinumab and Dupilumab
Neterton Syndrome
2023-12-19
Active Not RecruitingPreventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Child
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Biphenotypic Acute Leukemia
Phase 2 / Phase 32023-12-01
RecruitingLow Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome
Nijmegen Breakage Syndrome
Phase 22023-11-22
RecruitingPTCy and and Ruxolitinib for GVHD Prophylaxis After HSCT With Thymoglobulin in Conditioning Regimen in Patient
Inborn Errors of Immunity
Phase 22023-11-21
RecruitingAbdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification
Neuroblastoma, Ganglioneuroma, Ganglioneuroblastoma
2023-10-19
RecruitingInduction Chemoimmunotherapy for Patients With High-risk Neuroblastoma
Neuroblastoma, Ganglioneuroblastoma
Phase 32023-09-01
UnknownEvaluation of Subcutaneous Immunoglobulin Product Cutaquig in Terms of Safety and Efficacy in the Treatment of
Primary Immunodeficiency Diseases (PID)
2022-09-01
Active Not RecruitingPreventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibito
Acute Lymphoblastic Leukemia, Myeloblastic Leukemia, Biphenotypic Acute Leukemia
Phase 32022-08-23
RecruitingEfficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA)
Juvenile Nasopharyngeal Angiofibroma
Phase 32022-05-30
RecruitingB-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021
Non-hodgkin Lymphoma,B Cell, Burkitt Lymphoma, Primary Mediastinal Lymphoma
Phase 42022-05-25
UnknownLow Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and Adolesce
Chemotherapy-induced Nausea and Vomiting
Phase 32022-04-01
RecruitingCombined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 D
Acute Lymphoblastic Leukemia, Pediatric, ALL, Infants
Phase 32021-09-23
UnknownEx-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT
Acute Myeloid Leukemia, High Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, in Relapse
Phase 1 / Phase 22021-09-16
Not Yet RecruitingTotal Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia
Severe Congenital Neutropenia, GATA2 Deficiency
Phase 22021-04-14
CompletedVideoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia
Ataxia Telangiectasia, Dysmetria
2021-03-15
UnknownQuantitative MRI of Bone Marrow in Patients With Acute Lymphoblastic Leukemia
Acute Leukemia
N/A2021-02-22
UnknownEvaluation of Brain Changes in ALL Patients on Therapy
Acute Leukemia
N/A2021-02-16
UnknownQuantitative MRI of Bone Marrow Fat Fraction in Patients With Trepanobiopsy
Aplastic Anemia, Aplastic Anemia Idiopathic
N/A2021-02-16
UnknownDWI in the Diagnosis of Histological Types of Nephroblastoma in Children
Nephroblastoma (Wilms Tumour)
N/A2020-12-21
UnknownFecal Microbiome Transplantation (FMT) in Pediatric Patients Colonized With Antibiotic-resistant Pathogens Bef
Antibiotic Resistant Strain
Phase 22020-12-15
UnknownRituximab and Abatacept Effectiveness in Differential Treatment of Interstitial Lymphocytic Lung Disease in Ch
Interstitial Lymphocytic Lung Disease
2020-09-07
Active Not RecruitingBispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALL
B-ALL
Phase 1 / Phase 22020-07-27
UnknownLow Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome
Nijmegen Breakage Syndrome
Phase 22020-05-22
UnknownCovid-19 Associated Coagulopathy Predicted by Thrombodynamic Markers (CoViTro-I)
Coronavirus Disease 2019
2020-04-01
UnknownAcute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2019 Pilot
Childhood Acute Lymphoblastic Leukemia
N/A2020-02-01
UnknownMRI T2* Mapping of Myocardium, Liver, Pancreas and Pituitary Gland
Iron Overload
N/A2020-01-21
UnknownEfficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wi
Wiskott-Aldrich Syndrome
Phase 22019-11-05
UnknownPersonalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Ac
Refractory Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia
Phase 32019-10-15
UnknownModification of the Human Colon and Oral Microbiome by Allogenic HSCT
Human Microbiome, HSCT
2019-05-14
UnknownBrentuximab Vedotin as Alternative to the Autologous Stem Cell Transplantation in Relapsed and Refractory Clas
Hodgkin's Lymphoma
Phase 22019-05-14
UnknownPlerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients
Chronic Granulomatous Disease
Phase 22019-04-13
UnknownA Prospective Multicenter Clinical Trial of MRD-based Treatment Strategy in Children and Young Adults With AML
Acute Myeloid Leukemia, Childhood
Phase 32019-04-01
UnknownStudy of Crizotinib in Children and Adolescents With Myofibroblastic Tumors
Inflammatory Myofibroblastic Tumor
Phase 2 / Phase 32019-02-01
UnknownMetabolic Syndrome in Childhood Cancer Survivors
Metabolic Syndrome
2018-11-20
Unknownthe Efficacy and Safety of Sugammadex in Children 0-2 Years Old
Anesthesia, Pediatric Cancer, Pediatric Tumor
Phase 2 / Phase 32018-11-15
UnknownA Combination of Vemurafenib, Cytarabine and 2-chlorodeoxyadenosine in Children With LCH and BRAF V600E Mutati
Langerhans Cell Histiocytosis
Phase 22018-06-26
UnknownCD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL
B-cell Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Pediatric
Phase 1 / Phase 22018-05-14
CompletedClinical Use of Pathogen Reduced Red Blood Cell Suspension
Oncologic Disorders, Hematologic Diseases
Phase 32018-01-15
UnknownCreating a Decision Support System for the Corporate Management of Physical Therapy
Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Brain Tumor, Physical Activity
2017-11-01
CompletedCognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
Childhood Cancer, Cognitive Impairment, Motor Skills Disorders
N/A2017-11-01
UnknownEltrombopag+hATG+CsA vs. hATG+CsA in Children With Severe AA
Acquired Aplastic Anemia
Phase 32016-12-10
CompletedCD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT
Leukemia, Lymphoma, Myelodysplastic Syndromes
Phase 2 / Phase 32016-10-01
UnknownA Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS P
Wiskott-Aldrich Syndrome, Hematopoietic Stem Cell Transplantation, Graft Failure
Phase 22016-06-01
UnknownChildhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2015 (ALL-MB 2015)
Childhood Acute Lymphoblastic Leukemia
N/A2015-11-01
CompletedIL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease
Chronic Granulomatous Disease
EARLY_Phase 12015-09-25
CompletedMemory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantati
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Immune Deficiency Disease
Phase 1 / Phase 22014-08-01
CompletedTCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID
Primary Immune Deficiency Disorder, Hematopoietic Stem Cell Transplantation
Phase 2 / Phase 32012-07-01
CompletedRomiplostim Treatment for Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome.
Wiskott-Aldrich Syndrome
2012-04-01
UnknownChildhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008
Childhood Acute Lymphoblastic Leukemia
N/A2008-02-01