Clinical Trials Directory

Trials / Sponsors / Astellas Pharma Europe B.V.

Astellas Pharma Europe B.V.

Industry · 94 registered clinical trials.

StatusTrialPhaseStarted
CompletedA Study of ASP8302 in Participants With Underactive Bladder
Underactive Bladder
Phase 22018-11-20
CompletedA Study of MA-0217 (ASP1128) in Healthy Adult Subjects and Healthy Elderly Subjects
Healthy Volunteers
Phase 12017-11-20
CompletedA Study to Investigate Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of ASP6294 in the Treatment of
Bladder Pain Syndrome, Interstitial Cystitis
Phase 22017-09-28
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP7713 in Healthy Non-Japanese Adult and E
Healthy Volunteers
Phase 12017-05-23
TerminatedA Study To Assess The Efficacy And Safety Of Bismuth Tripotassium Dicitrate (De-Nol) In Combination With Panto
NSAID-induced Gastropathy
Phase 42017-03-03
CompletedA Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function
Normal Renal Function, Impaired Renal Function
Phase 12016-12-12
CompletedOpen-label Phase 3 Study With Mirabegron in Children From 3 to Less Than 18 Years of Age With Neurogenic Detru
Neurogenic Detrusor Overactivity
Phase 32016-06-17
CompletedA Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have
Type 2 Diabetes Mellitus
Phase 32016-05-11
CompletedA Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
Osteoarthritis of the Knee, Chronic Lower Back Pain
Phase 22016-02-16
CompletedA Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP6294 Administered Intr
Healthy Subjects, Pharmacokinetics of ASP6294
Phase 12016-01-01
CompletedA Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron Oral Suspension in Pediatric S
Overactive Bladder, Neurogenic Detrusor Overactivity
Phase 12015-12-17
CompletedA Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry i
Healthy Subjects
Phase 12015-05-01
CompletedFirst-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of P
Healthy Volunteers
Phase 12015-05-01
CompletedA Study to Evaluate ASP8232 as Add-On Therapy to Angiotensin Converting Enzyme Inhibitor (ACEi) or Angiotensin
Chronic Kidney Disease, Type 2 Diabetes
Phase 22015-03-17
CompletedA Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME
Diabetes Mellitus, Diabetic Macular Edema
Phase 22015-01-12
CompletedA Study to Investigate the Safety and Efficacy of Fidaxomicin (Oral Suspension or Tablets) and Vancomycin (Ora
Clostridium Difficile-associated Diarrhea (CDAD)
Phase 32015-01-09
CompletedA Combined Single and Multiple Ascending Dose Study of ASP6858 in Healthy Subjects
Healthy Volunteers
Phase 12015-01-01
CompletedRoxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis
Anemia, End Stage Renal Disease (ESRD)
Phase 32014-11-21
TerminatedA Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP2205 in Healthy Young Males and Females
Healthy Subjects, Pharmacokinetics of ASP2205
Phase 12014-11-01
WithdrawnA Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP3700 in Healthy Subjec
Healthy Volunteers, Pharmacokinetics of ASP3700
Phase 12014-11-01
CompletedA Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cance
Castration-Resistant Prostate Cancer, Prostate Cancer
Phase 22014-09-23
CompletedA Study to Evaluate Quality of Life in Patients Switched to Solifenacin From Other Antimuscarinics
Urinary Bladder, Overactive
2014-06-01
CompletedA Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Metastatic Castration-Resistant Prostate Cancer
Phase 42014-05-23
CompletedStudy to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentration
Healthy Subjects, Pharmacokinetics, Drug-Drug Interaction (DDI)
Phase 12014-05-01
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Multiple Ascending Doses of ASP7962 in
Healthy Volunteers, Pharmacokinetics of ASP7962
Phase 12014-05-01
CompletedA Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP3700 in Healthy Male Subjects
Healthy Volunteers, Pharmacokinetics of ASP3700
Phase 12014-05-01
TerminatedA Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmac
Pharmacokinetics of ASP7657, Pharmacodynamics of ASP7657, Healthy Subjects
Phase 12014-04-01
CompletedA Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects
Pharmacokinetics, DDI (Drug-Drug Interaction), Healthy Subjects
Phase 12014-04-01
CompletedA Multinational Study Comparing the Long-term Efficacy and Safety of Two Medicines, Solifenacin Succinate and
Urinary Bladder Overactive, Overactive Bladder, Urgency Incontinence
Phase 32014-03-17
CompletedRoxadustat in the Treatment of Anemia in Chronic Kidney Disease (CKD) Patients, Not on Dialysis, in Comparison
Anemia in Chronic Kidney Disease in Non-dialysis Patients
Phase 32014-03-12
CompletedStudy to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy S
Healthy Subjects, Pharmacokinetics, Drug-Drug Interaction (DDI)
Phase 12014-03-01
CompletedA Study Into Pain Relief Given by ASP8477 for Peripheral Neuropathic Pain (Either Post-herpetic Neuralgia or P
Post-Herpetic Neuralgia (PHN), Neuropathic Pain, Painful Diabetic Peripheral Neuropathy (PDPN)
Phase 22014-02-24
CompletedThis Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and
Urinary Bladder Overactive, Urinary Bladder Diseases\Urologic Diseases, Overactive Bladder
Phase 32013-11-05
CompletedA Clinical Trial to Investigate Safety and Tolerability of ASP7962 in Healthy Humans
Safety, Tolerability, Pharmacokinetics of ASP7962
Phase 12013-11-01
CompletedA Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan
Pharmacokinetics of Dextromethorphan, Pharmacokinetics of Caffeine, Prostate Cancer
Phase 12013-10-02
CompletedA Clinical Study to Investigate How Solifenacin Fluid is Taken up, How Long it Stays in the Body and How Effec
Neurogenic Detrusor Overactivity, Pediatric
Phase 32013-09-25
CompletedA Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of ASP8232 in Subjects With Renal Impair
Healthy Subjects, Pharmacokinetics of ASP8232, Pharmacodynamics of ASP8232
Phase 1 / Phase 22013-09-16
CompletedRoxadustat in the Treatment of Anemia in Chronic Kidney Disease Patients Not Requiring Dialysis
Anemia in Chronic Kidney Disease in Non-dialysis Patients
Phase 32013-09-03
CompletedAn Observational Study Looking at How Well the Drug Eligard Works and How Well it is Tolerated by the Body of
Advanced Prostate Carcinoma
2013-09-01
CompletedA Study to Evaluate the Dose-proportionality and Effects of FG-4592 in Healthy Young and Elderly Male and Fema
PK for FG-4592, Healthy Subjects
Phase 12013-09-01
CompletedA Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With M
PK of FG-4592, Hepatic Insufficiency, Healthy Subjects
Phase 12013-09-01
CompletedA Study to Evaluate the Effects of Multiple Doses of FG-4592 on the Exposure, Safety and Tolerability and Effe
Pharmacokinetics of FG-4592, Healthy Subjects
Phase 12013-09-01
CompletedA Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerab
Severe Hepatic Impairment, Normal Hepatic Function
Phase 12013-08-01
CompletedA Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in
Drug-Drug Interaction (DDI), Healthy Subjects, Pharmacokinetics of Enzalutamide
Phase 12013-07-01
CompletedA Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Mal
Drug-Drug Interaction (DDI), Intestinal Absorption, Healthy Subjects
Phase 12013-02-01
CompletedA Study to Assess the Effectiveness and Safety of Different Doses of ASP1707 Compared to Placebo for Endometri
Endometriosis
Phase 22012-12-04
CompletedRelative Bioavailability Study of Enzalutamide in Prostate Cancer Patients
Prostate Cancer, Pharmacokinetics of Enzalutamide
Phase 12012-11-01
CompletedA Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dos
Healthy Subjects, Castration Resistant Prostate Cancer (CRPC), Relative Bioavailability
Phase 12012-11-01
CompletedA Study to Investigate How Safe and Effective Solifenacin Solution is in Treating Children/Adolescents With Sy
Urinary Bladder, Overactive
Phase 32012-10-04
CompletedShort and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents
Systemic Fungal Infections
2012-10-01
CompletedA Study to Investigate the Appearance and Disappearance of ASP3652 in Blood and Spinal Fluid in Healthy Male S
Pharmacokinetics of ASP3652, Pharmacodynamics of ASP3652, Healthy Subjects
Phase 12012-09-01
CompletedA Study to Compare How Much Solifenacin Succinate and Mirabegron Reach the Blood When Administered Together as
Phase 1, Bioavailability, Healthy Subjects
Phase 12012-09-01
CompletedA Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Participan
Neurogenic Detrusor Overactivity
Phase 32012-08-14
CompletedA Study to Assess the Safety, Tolerability and Effects of Single Ascending Doses of ASP3652 in Healthy Subject
Pharmacokinetics, Pharmacodynamics, Healthy Subjects
Phase 12012-08-01
CompletedA Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed
Pharmacokinetics, Pharmacodynamics, Healthy Subjects
Phase 12012-07-01
CompletedA Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administratio
Healthy Subjects, Pharmacokinetics of ASP3652
Phase 12012-07-01
CompletedA Study to Investigate How Effective and Safe Solifenacin Succinate Suspension is in Treating Children/Adolesc
Urinary Bladder, Overactive
Phase 32012-06-07
CompletedRibomustin in the First Line Therapy of Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
2012-06-01
CompletedA Randomized Study Comparing Placebo and ASP3652 in the Treatment of Women With Bladder Pain Syndrome / Inters
Cystitis, Interstitial, Urinary Bladder Disease, Pain
Phase 22012-05-31
CompletedRibomustin in the Second Line Therapy of Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma
Lymphoma, Non-Hodgkin
2012-05-01
CompletedA Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the E
Drug-Drug Interaction (DDI), Healthy Subjects
Phase 12012-04-01
TerminatedTo Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Diffic
Clostridium Difficile
2012-03-01
CompletedTreatment of Symptoms in Male Patients With Lower Urinary Tract Symptoms (LUTS) Predominant Storage Symptoms (
Lower Urinary Tract Predominant Storage Symptoms
2011-12-01
CompletedObservational, Non-interventional, Non Comparative Real Life Data Collection of Depo-Eligard® 7.5 mg, 22.5 mg
Prostate Cancer
2011-12-01
CompletedA Phase 1 Study to Investigate the Mechanism of Action of Ipragliflozin
Type 2 Diabetes Mellitus
Phase 12011-10-27
CompletedHepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Heal
Pharmacokinetics of MDV3100, Healthy Subjects, Kidney Diseases
Phase 12011-10-01
CompletedA Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioa
Pharmacokinetics of ASP1707
Phase 12011-08-01
CompletedDrug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole
Healthy Subjects, Pharmacokinetics, Drug-Drug Interaction
Phase 12011-08-01
CompletedDrug-drug Interaction Study With MDV3100 and a Cocktail of Substrates
Pharmacokinetics of MDV3100, Castration Resistant Prostate Cancer (CRPC)
Phase 12011-07-25
CompletedDrug to Drug Interaction Study With Ipragliflozin and Furosemide
Healthy Subjects, Pharmacokinetics of Ipragliflozin
Phase 12011-07-01
CompletedA Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects
Healthy Subjects
Phase 12011-06-01
CompletedAbsolute Bioavailability Study With Ipragliflozin
Bioavailability of Ipragliflozin, Healthy Subjects
Phase 12011-06-01
CompletedA Study to Explore the Routes of Elimination of MDV3100
Healthy Subjects, Pharmacokinetics of MDV3100
Phase 12011-04-01
CompletedA Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in
Urologic Diseases, Urinary Bladder Diseases, Urological Manifestations
Phase 22011-03-29
CompletedA Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug
Pharmacokinetics of ASP8477, Pharmacodynamics of ASP8477
Phase 12010-11-01
CompletedA Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in He
Pharmacokinetics of ASP1707, Pharmacodynamics of ASP1707
Phase 12010-06-01
CompletedLong Term Study of Solifenacin Succinate and Tamsulosin Hydrochloride Oral Controlled Absorption System (OCAS)
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Phase 32010-04-26
CompletedA Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the In
EC905, Pharmacokinetics, Multiple Dose
Phase 12010-04-01
CompletedA Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered i
EC905, Pharmacokinetics, Healthy Subjects
Phase 12010-04-01
CompletedA Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tams
EC905, Pharmacokinetics, Healthy Subjects
Phase 12010-03-01
CompletedStudy of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Phase 32010-01-11
CompletedStudy Evaluating Safety, Tolerability and Efficacy of YM150 in Subjects With Acute Coronary Syndromes
Acute Coronary Syndrome
Phase 22009-09-01
CompletedA Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosi
Drug-Drug Interaction (DDI), Healthy Subjects
Phase 12009-08-01
CompletedA Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male a
Healthy Subjects, Pharmacokinetics of ASP3652, Pharmacodynamics of ASP3652
Phase 12009-05-01
CompletedA Study Evaluating Efficacy and Safety of YM150 Compared to Enoxaparin in Subjects Undergoing Hip Replacement
Venous Thromboembolism, Arthroplasty, Replacement, Hip
Phase 2 / Phase 32009-04-01
CompletedEC905 Pharmacokinetic Profile Study
Phase 1, Healthy, Benign Prostatic Hyperplasia
Phase 12009-03-01
CompletedA Study to Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment C
Pharmacokinetics, Healthy Subjects, Mild and Moderate Hepatic Impairment
Phase 12008-11-01
CompletedA Study to Evaluate the Effect of a Single Dose of Digoxin on the Actions in the Bodies of Healthy Subjects Af
Healthy
Phase 12008-09-01
CompletedLocobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatit
Dermatitis, Atopic
Phase 42008-03-01
CompletedA Study to Find Out How YM150 is Absorbed Into and Eliminated From the Body in Healthy Male Subjects
Pharmacokinetics, Healthy Male Subjects
Phase 12007-02-01
CompletedA Study to Evaluate the Safety and Tolerability of YM150 in Healthy Caucasian and Japanese Male and Female Sub
Pharmacokinetics, Pharmacodynamics, Healthy Subjects
Phase 12006-06-01
CompletedA Study to Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178
Pharmacokinetics of YM178, Healthy Subjects
Phase 12005-01-01
CompletedStudy to Test the Efficacy and Safety of YM178 in Subjects With Symptoms of Overactive Bladder
Urinary Bladder, Overactive
Phase 22004-04-05
CompletedA Study to Assess the Systemic Pharmacokinetics, Metabolism and Excretion Routes of YM178 in Man, After Admini
Metabolic Processes
Phase 12003-01-01