Clinical Trials Directory

Trials / Sponsors / Amicus Therapeutics

Amicus Therapeutics

Industry · 42 registered clinical trials5 currently recruiting.

StatusTrialPhaseStarted
RecruitingA Study of Patients With Fabry Disease (US Specific)
Fabry Disease
2026-02-13
RecruitingA Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants
Fabry Disease
Phase 32026-01-08
RecruitingA Global Prospective Observational Study of Women With Fabry Disease and Their Infants During Pregnancy and Br
Fabry Disease
2025-03-18
RecruitingA Global Prospective Observational Registry of Patients With Pompe Disease
Pompe Disease
2024-02-16
RecruitingA Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD
Glycogen Storage Disease Type II Infantile Onset
Phase 32023-07-18
CompletedUnderstanding Fabry Disease Therapy Choices Through the Eyes of the Patients
Fabry Disease
2023-03-01
Active Not RecruitingA Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease
Fabry Disease
Phase 32022-10-31
CompletedA Study to Describe the Experience of Both Patients and Their Clinicians in the Treatment of Fabry Disease Wit
Fabry Disease
2020-03-01
Active Not RecruitingZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y
Pompe Disease (Late-onset)
Phase 32020-02-13
CompletedA Study to Assess the Long-term Safety and Efficacy of ATB200/AT2221 in Adult Subjects With Late-Onset Pompe D
Pompe Disease (Late-onset)
Phase 32019-12-18
CompletedSafety, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged >12 Years) With Fabry Disease
Fabry Disease
Phase 32019-10-11
CompletedA Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Diseas
Pompe Disease (Late-onset)
Phase 32018-12-04
CompletedSafety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to <18 Y
Fabry Disease
Phase 32018-09-27
TerminatedSTRIDE Study - A Study in Subjects With LOPD Who Are Currently Being Treated With ERT
Late-onset Pompe Disease
2017-12-08
CompletedSurvey to Identify Burdens and Unmet Needs of Patients With Epidermolysis Bullosa
Epidermolysis Bullosa
2017-04-02
CompletedFirst-In-Human Study to Evaluate Safety, Tolerability, and PK of Intravenous ATB200 Alone and When Co-Administ
Pompe Disease
Phase 1 / Phase 22016-04-01
CompletedOpen-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry Disease
Fabry Disease
Phase 32015-03-14
CompletedA Phase 1 Study To Evaluate the Safety of Migalastat Hydrochloride Given Intravenously to Healthy Volunteers
Fabry Disease
Phase 12014-03-01
CompletedDrug-drug Interaction Study
Pompe Disease
Phase 22011-10-31
TerminatedOpen-Label Phase 3 Long-Term Safety Study of Migalastat
Fabry Disease
Phase 32011-10-14
CompletedMigalastat Food Effect Study
Fabry Disease
Phase 12011-10-01
CompletedStudy to Compare the Efficacy and Safety of Oral AT1001 and Enzyme Replacement Therapy in Patients With Fabry
Fabry Disease
Phase 32011-09-08
CompletedA Phase I, Randomized, Single-Blind, Four-Period Cross-Over, Placebo-Controlled, Dose-Escalation Study to Eval
Fabry Disease
Phase 12011-09-01
CompletedSafety and Pharmacokinetics of AT1001 (Migalastat HCl) in Healthy Subjects and Subjects With Impaired Renal Fu
Fabry Disease
Phase 12011-08-01
CompletedA Study to Assess the Absorption, Metabolism and Excretion of Migalastat Hydrochloride (AT1001-014)
Fabry Disease
Phase 12011-08-01
CompletedDrug-Drug Interaction Study Between AT1001 (Migalastat Hydrochloride) and Agalsidase in Participants With Fabr
Fabry Disease
Phase 22011-02-02
CompletedStudy of the Effects of Oral AT1001 (Migalastat Hydrochloride) in Patients With Fabry Disease
Fabry Disease
Phase 32009-10-23
CompletedA Long-Term Extension Study of AT2101 (Afegostat Tartrate) in Type 1 Gaucher Patients
Gaucher Disease, Type 1 Gaucher Disease, Gaucher Disease, Type 1
Phase 22009-05-11
TerminatedA Study in Type 1 Gaucher Patients to Evaluate the Pharmacokinetics, Safety and Pharmacodynamics of AT2101
Type 1 Gaucher Disease
Phase 12009-04-01
TerminatedStudy to Evaluate the Safety of AT2220 (Duvoglustat) in Pompe Disease
Pompe Disease
Phase 22008-12-08
CompletedA Study of Oral AT2101 (Afegostat Tartrate) in Treatment-naive Patients With Gaucher Disease
Gaucher Disease, Type 1 Gaucher Disease, Gaucher Disease, Type 1
Phase 22008-06-11
TerminatedOpen-label Long-term Safety Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease Who
Fabry Disease
Phase 22007-09-17
CompletedA Study to Evaluate the Effects of Pharmacological Chaperones in Cells From Patients With Pompe Disease
Pompe Disease, Glycogen Storage Disease Type II
2007-08-01
CompletedA Study of AT2101 (Afegostat Tartrate) in Adult Patients With Type 1 Gaucher Disease Currently Receiving Enzym
Gaucher Disease, Type 1, Type 1 Gaucher Disease, Gaucher Disease
Phase 22007-03-23
CompletedA 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Female Participants With Fa
Fabry Disease
Phase 22006-09-07
CompletedStudy to Evaluate Blood Cell Lines From Patients With Gaucher Disease
Gaucher Disease
2006-07-01
CompletedA 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Dis
Fabry Disease
Phase 22006-06-27
CompletedA 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Dis
Fabry Disease
Phase 22006-05-09
CompletedA Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease
Fabry Disease
Phase 22006-01-02
AvailableExpanded Access for ATB200/AT2221 for the Treatment of IOPD
Pompe Disease Infantile-Onset
AvailableExpanded Access for ATB200/AT2221 for the Treatment of Pompe Disease
Pompe Disease
AvailablePhysician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease
Fabry Disease