| Recruiting | Efficacy and Safety of Vaginal Radiofrequency for Vulvovaginal Atrophy in Breast Cancer Patients NCT06900374 | Centre Oscar Lambret | N/A |
| Completed | A Comparison of Hyaluronic Acid and Estradiol Treatment in Vulvovaginal Atrophy. NCT06144814 | Koru Health Groups | N/A |
| Completed | Combination of BTL-785F and HPM-6000UF Devices for Women's Intimate Wellness NCT06846216 | BTL Industries Ltd. | N/A |
| Completed | Validation of the DIVA (Day to Day Impact of Vaginal Aging) Questionnaire for Portuguese Women NCT07250490 | Instituto Politécnico de Leiria | — |
| Completed | Vulvovaginal Atrophy Questionnaire (VVAQ): Psychometric Validation of a Novel PROM NCT04746456 | Massachusetts General Hospital | — |
| Completed | Study of DARE-HRT1 Over 12 Weeks in Healthy PostMenopausal Women NCT05367973 | Daré Bioscience, Inc. | Phase 1 / Phase 2 |
| Recruiting | GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocr NCT05562518 | University Hospital, Ghent | Phase 4 |
| Completed | Non-hormonal Medical Device for Treatment of Vulvovaginal Atrophy (VVA) in Post-Menopausal Women NCT04887701 | Madorra | N/A |
| Unknown | Effects of Visnadin, Ethyl Ximeninate, Coleus Barbatus and Millet in Emulgel on Sexual Function in Postmenopau NCT04579991 | Chulalongkorn University | N/A |
| Unknown | Clinical Study to Evaluate the Efficacy of Prasterone Treatment for Atrophy Vulvovaginal in Postmenopausal Wom NCT04898556 | Dr. Santiago Palacios | Phase 3 |
| Completed | Local DHEA and Estradiol on Dyspareunia in Postmenopausal Women NCT05586711 | Angelica Lindén Hirschberg | Phase 4 |
| Withdrawn | Photobiomodulation Effect on Vulvovaginal Atrophy in Postmenopausal Women. NCT04487392 | University of Nove de Julho | Phase 2 |
| Completed | Pilot Clinical Trial of IDRACARE® in Moderate to Severe Symptoms of Vulvovaginal Atrophy NCT04766957 | Procare Health Iberia S.L. | N/A |
| Completed | A Phase 1, Open-Label, Parallel Group Study to Evaluate the Pharmacokinetics and Safety of DARE-HRT1 in Health NCT05418426 | Daré Bioscience, Inc. | Phase 1 |
| Completed | Women's Satisfaction and Adherence to Vulvovaginal Atrophy Treatments NCT04607707 | Shionogi | — |
| Completed | Investigation of Efficacy and Tolerability of a Lactic Acid Containing Vaginal Suppository in Post-menopausal NCT04222647 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Phase 2 |
| Completed | Efficacy and Safety of Hyaluronic Acid Injection on Symptoms of Vulvovaginal Atrophy in Postmenopausal Women NCT04219722 | Laboratoires Vivacy | N/A |
| Completed | Evaluation of the Acceptability and Efficacy of 10 Micrograms of Estradiol Vaginal Tablets vs Promestriene Vag NCT04232813 | Instituto Palacios | Phase 3 |
| Completed | Study to Evaluate Estradiol Vaginal Tablets vs Promestriene Vaginal Cream NCT03385551 | Instituto Palacios | — |
| Unknown | Performance and Safety of Class IIb MD Celegyn® in VVA NCT03823560 | Nathura S.p.A | N/A |
| Completed | RF and PEMF for Treatment of Vaginal Laxity and Mons Pubis and Labia for Improvement of Skin Laxity NCT04210583 | Venus Concept | N/A |
| Completed | Use of Fractional CO2 Laser for the Treatment of Vulvovaginal Atrophy: a Double-blinded Randomized Placebo-con NCT04021966 | prof. dr. Jan Deprest | N/A |
| Unknown | Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy NCT03782480 | Center for Vulvovaginal Disorders | Phase 3 |
| Completed | Performance and Safety of Hyalo Gyn Gel on the Treatment of Vaginal Atrophy in Postmenopausal Women NCT04355403 | Fidia Farmaceutici s.p.a. | N/A |
| Completed | Safety, Efficacy and Usage Compliance of the Silk'n Tightra Device NCT03900143 | Home Skinovations Ltd. | N/A |
| Completed | Multi-polar RF and PEMF for Treatment of Symptoms Associated With Vulvovaginal Atrophy NCT03725410 | Venus Concept | N/A |
| Withdrawn | Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Can NCT03666819 | Mayo Clinic | Phase 2 |
| Terminated | Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment NCT03682601 | GTO Pharmaceutical, LLC | Phase 2 |
| Unknown | Laser Therapy for Vulvovaginal Symptoms in Breast Cancer Patients NCT03628092 | Royal North Shore Hospital | N/A |
| Completed | Multi-polar RF and PEMF for Treatment of Vaginal Laxity and Mons Pubis and Labia for Improvement of Skin Laxit NCT03536585 | Venus Concept | N/A |
| Completed | Efficacy and Safety of HYDEAL-D Vaginal Pessaries Application on the Treatment of Vaginal Atrophy in Post-meno NCT03557398 | Fidia Farmaceutici s.p.a. | N/A |
| Completed | Multi-polar RF and PEMF for Treatment of Vulvovaginal Atrophy NCT04607798 | Venus Concept | N/A |
| Completed | High Tone Pelvic Floor Dysfunction NCT03083262 | St. Louis University | — |
| Unknown | Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy NCT03271944 | SHERRY Thomas | N/A |
| Completed | Visnadine, Prenylflavonoids and Bovine Colostrum to Treat Vulvovaginal Atrophy in Postmenopausal Women NCT03281655 | University of Messina | Phase 2 |
| Withdrawn | Vaginal Progesterone Versus Placebo for the Treatment of Vaginal Atrophy NCT02460302 | Mount Sinai Hospital, Canada | Phase 2 |
| Completed | Investigation of Non-inferiority of Treatment of Vulvovaginal Dryness With WO2085 Moisturising Cream in Compar NCT03044652 | Dr. August Wolff GmbH & Co. KG Arzneimittel | Phase 4 |
| Completed | Study to Evaluate Efficacy of Vagitocin in Postmenopausal Women With Vulvovaginal Atrophy Symptoms NCT04629885 | PepTonic Medical AB | Phase 2 |
| Completed | A Safety and Efficacy Study of Estradiol Vaginal Capsule in Postmenopausal Women With Vulvovaginal Atrophy NCT02670785 | Warner Chilcott | Phase 2 |
| Completed | Vulvoscopy Changes of the Vulva, Vestibule and Vagina With Daily Ospemifene in Women With Dyspareunia From VVA NCT02784613 | Sue Goldstein | Phase 4 |
| Completed | Evaluation of Fractional CO2 Laser Treatment Efficacy and Comparison to Vaginal Estrogen Therapy in Postmenopa NCT02419729 | Faculdade de Medicina do ABC | Phase 3 |
| Completed | Estradiol Vaginal Softgel Capsules in Treating Symptoms of Vulvar and Vaginal Atrophy in Postmenopausal Women NCT02253173 | TherapeuticsMD | Phase 3 |
| Completed | Clinical Investigation to Assess the Safety and Efficacy of the Laser for the Treatment of Vulvovaginal Atroph NCT02085980 | El. En. SpA | N/A |
| Completed | TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vagin NCT02449902 | TherapeuticsMD | Phase 2 |
| Completed | Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women With Dyspare NCT01845649 | Warner Chilcott | Phase 3 |
| Completed | Multicenter Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women NCT01816139 | Warner Chilcott | Phase 3 |
| Completed | Evaluate Long-Term Safety and Efficacy WC3011 (Estradiol Vaginal Cream) NCT01455597 | Warner Chilcott | Phase 3 |
| Completed | Postpartum Dyspareunia Resulting From Vaginal Atrophy NCT01319968 | Meir Medical Center | — |
| Completed | Investigation on the Efficacy of WO 2085 Moisturising Cream for Breast Cancer Patients Suffering From Vulvovag NCT03593122 | Dr. August Wolff GmbH & Co. KG Arzneimittel | N/A |
| Completed | Vaginal Microbiota Among Postmenopausal Women NCT01084616 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |