| Recruiting | Topical Ketotifen 0.25% for Secondary Vestibulodynia NCT07257029 | Center for Vulvovaginal Disorders | Phase 2 |
| Recruiting | A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia) NCT07391241 | Initiator Pharma | Phase 2 |
| Not Yet Recruiting | Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial NCT07260825 | TriHealth Inc. | Phase 2 / Phase 3 |
| Not Yet Recruiting | Light Emitting Diode in the Treatment of Vulvodynia NCT06337448 | Centro de Atenção ao Assoalho Pélvico | N/A |
| Recruiting | Young Vulvodynia: Effect and Efficacy of Multimodal Treatment. NCT07092332 | Region Örebro County | N/A |
| Recruiting | Biomodulation and Rehabilitation Interventions to TarGet Pelvic Health NCT06660212 | University of Ottawa | N/A |
| Recruiting | Vestibulodynia At High Resolution: Omics Approach to Improve Diagnosis NCT06865963 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Enrolling By Invitation | Vaginal Ecosystem and Network in the United States Study NCT06472765 | Vaginal Biome Science | — |
| Completed | Analysis of the Understanding of the French Version of the Vulvar Pain Assessment Questionnaire NCT06476002 | Hopital Foch | N/A |
| Completed | Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vul NCT06138171 | University of Roma La Sapienza | — |
| Recruiting | Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia NCT05955313 | Medical University of Lublin | Phase 2 |
| Active Not Recruiting | Efficacy of High Intensity Laser for Provoked Vestibulodynia NCT05597358 | Université de Sherbrooke | N/A |
| Recruiting | Vestibulectomy Surgical Techniques Comparison Study NCT05343182 | Oregon Health and Science University | N/A |
| Unknown | An Investigation of Nomothetic Versus Idiographic Assessment in Chronic Pain NCT05518630 | Uppsala University | — |
| Completed | Effects of Flourish HEC on Localized Provoked Vulvodynia NCT05478746 | Vaginal Biome Science | N/A |
| Terminated | Therapeutic Efficacy of Erbium:YAG Laser in Postpartum Patients With Episiotomy Scars NCT05793476 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | Acupuncture in a Multidisciplinary Approach for Vulvodynia and Chronic Pelvic Pain NCT05324280 | Medical University of Graz | N/A |
| Completed | Pelvic Floor Myofascia: A New Player Involved in Vulvodynia NCT05350618 | Université de Sherbrooke | — |
| Terminated | Vulvodynia Pain Thresholds NCT04461210 | State University of New York at Buffalo | — |
| Recruiting | Lasertherapy for Vulvodynia NCT04711369 | Medical University of Graz | N/A |
| Unknown | Somatocognitive Therapy in Treatment of Provoked (Localized) Vestibulodynia - Randomized Clinical Trial (ProLo NCT04613713 | Oslo Metropolitan University | N/A |
| Completed | High-level Laser for Provoked Vestibulodynia NCT04502810 | Université de Sherbrooke | N/A |
| Terminated | Effect of Spinal Manipulation on Vulvar Pain NCT04016467 | University of Mary Hardin-Baylor | N/A |
| Completed | CO2 Laser vs Lidocaine for Vestibulodynia in Premenopausal Women NCT05336825 | Atlantic Health System | N/A |
| Completed | Vulvodynia: Identification of Potential Relevant Biomarkers NCT02981433 | St. Louis University | — |
| Completed | Validation of Patient Reported Outcome Measures for Use in Vulvodynia NCT03770169 | Ipsen | — |
| Active Not Recruiting | Multidisciplinary Treatment of Chronic Vulvar Pain NCT03640624 | Norwegian University of Science and Technology | N/A |
| Terminated | Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment NCT03682601 | GTO Pharmaceutical, LLC | Phase 2 |
| Terminated | Dysport in Vulvodynia Phase II Study NCT03598777 | Ipsen | Phase 2 |
| Completed | Acupuncture for Vulvodynia: A Pre-pilot Study NCT02704234 | University of Illinois at Chicago | N/A |
| Completed | Effect of Acupuncture on Patient Vulvodynia Outcomes NCT03364127 | University of Illinois at Chicago | N/A |
| Unknown | Effect of Two Acupuncture Protocols on Vulvodynia NCT03481621 | McLean Center for Complementary and Alternative Medicine, PLC | N/A |
| Completed | Is Localized Provoked Vulvodynia Caused by Laxity of the Utero-Sacral Ligaments? NCT03197337 | Western Galilee Hospital-Nahariya | N/A |
| Unknown | Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled Trial NCT02871661 | University of Campinas, Brazil | Phase 3 |
| Completed | Botulinum Toxin A as a Treatment for Provoked Vestibulodynia NCT04057755 | Karolinska Institutet | Phase 3 |
| Completed | Placebo-controlled RCT of Botulinum Toxin A as a Treatment for Provoked Vestibulodynia NCT02773641 | Karolinska Institutet | Phase 3 |
| Terminated | Vulvar Mucosal Specialty Clinic Chart Review NCT02881229 | Northwestern University | — |
| Completed | An Internet-based Information Platform for Vulvodynia Patients NCT02809612 | Uppsala University | N/A |
| Unknown | Psychosocial Factors and Central Sensitization in Chronic Pelvic Pain NCT02856334 | University of Valencia | — |
| Unknown | Dysbiosis in Localized Provoked Vulvodynia (LPV) NCT02393911 | Western Galilee Hospital-Nahariya | Phase 3 |
| Completed | Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia NCT01935063 | Université de Montréal | N/A |
| Completed | Provoked, Localized Vulvodynia Treatment With Acupuncture and Lidocaine Pilot Study NCT01996384 | Oregon College of Oriental Medicine | Phase 1 |
| Completed | Profiling Vulvodynia Based on Neurobiological and Behavioral Endophenotypes NCT02733172 | University of California, Los Angeles | — |
| Recruiting | Prospective Data Bank Creation to Study Vaginal Conditions NCT01829204 | Texas Tech University Health Sciences Center | — |
| Withdrawn | A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized Vulvodynia NCT01048177 | Scripps Health | Phase 2 |
| Completed | Physiotherapy Intervention for Provoked Vulvar Vestibulodynia NCT01628679 | University of British Columbia | N/A |
| Completed | A Trial of Gabapentin in Vulvodynia: Biological Correlates of Response NCT01301001 | University of Tennessee | N/A |
| Completed | Pregnancy, Childbirth Intentions and Outcomes Under Sexual Pain NCT01731288 | University of British Columbia | — |
| Completed | Acupuncture for the Treatment of Vulvodynia NCT02197429 | Schlaeger, Judith M., CNM, LAc, PhD | N/A |
| Completed | Therapy to Prevent Sexual Pain in Breast Cancer Survivors NCT01539317 | OHSU Knight Cancer Institute | Phase 3 |
| Completed | Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis NCT02732145 | Ginekološka Poliklinika Dr. Vesna Harni | N/A |
| Completed | Multi Modal Imaging: An MRI Study to Investigate Differences in the Structure and the Function of the Brain at NCT01517516 | University of California, Los Angeles | — |
| Terminated | Study of Emu Oil vs. Placebo for Vulvar Pain in Women. NCT01295268 | Corewell Health East | N/A |
| Completed | Savella in Treatment for Provoked Vestibulodynia NCT01304589 | University of Tennessee | Phase 3 |
| Completed | Women's Health Study: Immunological Factors and Risk of Vulvodynia NCT02404961 | University of Minnesota | — |
| Completed | Enoxaparin as Treatment for Vulvodynia NCT00874484 | Western Galilee Hospital-Nahariya | Phase 2 |
| Terminated | Pregabalin for the Treatment of Vulvodynia NCT00853229 | The Cleveland Clinic | Phase 2 |
| Completed | The Effectiveness of Vestibulectomy NCT00873301 | Western Galilee Hospital-Nahariya | N/A |
| Completed | CC-10004 For The Treatment Of Vulvodynia NCT00814632 | Kenneth Peters, MD | Phase 2 |
| Completed | Search for Genetic Basis of Vulvodynia NCT01664962 | Western Galilee Hospital-Nahariya | — |
| Completed | Relationship: Interstitial Cystitis & Vulvodynia-Part 2 NCT00751010 | Corewell Health East | — |
| Completed | Safety and Efficacy of Two Vaginal Products Versus Placebo in Patients With Vaginal Discomfort NCT00590590 | Lumara Health, Inc. | Phase 2 |
| Completed | Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis NCT00496184 | Western Galilee Hospital-Nahariya | Phase 3 |
| Completed | A Search for Helicobacter Pylori in Localized Vulvodynia NCT00501774 | Western Galilee Hospital-Nahariya | — |
| Completed | A Randomized Clinical Trial for Women With Vulvodynia NCT00607490 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | N/A |