| Not Yet Recruiting | Effects of Mobilization Using a Powered Lower-limb Exoskeleton With Prolonged Mechanical Ventilation NCT07445035 | Fu Jen Catholic University | N/A |
| Not Yet Recruiting | Comparison of Diaphragm Ultrasound and RSBI for Predicting Weaning Success in Mechanically Ventilated ICU Pati NCT07120438 | Gadjah Mada University | — |
| Recruiting | A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score NCT07098611 | Medipol University | — |
| Recruiting | Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients NCT06499389 | Hospices Civils de Lyon | N/A |
| Not Yet Recruiting | Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Pa NCT06653933 | University Hospital, Grenoble | — |
| Active Not Recruiting | Association Between P0.1 and Extubation Failure in Adult Patients With Acute Hypoxemic Respiratory Failure. A NCT06662201 | Argentinian Intensive Care Society | — |
| Completed | Correlation Analysis Between Mostcare Parameters and Spontaneous Breathing Trial in Patients After Cardiac Sur NCT06230497 | Peking Union Medical College Hospital | — |
| Recruiting | Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound NCT06321848 | Hanoi Medical University | — |
| Completed | Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial NCT05999526 | Centro Hospitalar Unimed de Joinville | N/A |
| Completed | Home-based Optimization of Mechanical Ventilation in Children NCT06055413 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | Extubation Guided by Bedside Ultrasound NCT05674812 | Lili Jia | — |
| Completed | Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training NCT05380687 | University Hospital, Antwerp | N/A |
| Unknown | ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure NCT05114551 | University Hospital, Clermont-Ferrand | — |
| Completed | Totally Transdermal Sedation in the Weaning From Remifentanil Infusion NCT04204967 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 |
| Completed | Physiologic Effects of High-flow Nasal Cannula Versus Standard Oxygen Therapy Postextubation in Critically Ill NCT04711759 | Pontificia Universidad Catolica de Chile | N/A |
| Unknown | Pediatric Ventilation Weaning NCT04023643 | São Paulo State University | N/A |
| Active Not Recruiting | Spontaneous Breathing Trial With T-piece or Inspiratory Pressure Augmentation NCT04222205 | National Taiwan University Hospital | N/A |
| Completed | The Role of Chest Electrical Impedance Tomography in the Pediatric Ventilator Weaning NCT04011852 | University of Sao Paulo General Hospital | — |
| Completed | Use of Transient Elastogaphy to Assess Diaphragm Function in Mechanically Ventilated Patients NCT03832231 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Voices of Patients' Relatives to Support Weaning From Mechanical Ventilation NCT03795623 | University of Erlangen-Nürnberg Medical School | N/A |
| Unknown | Assessments of Diaphragm-pleural Mechanics During the Weaning From Prolonged Mechanical Ventilation NCT03842280 | National Taiwan University Hospital | — |
| Completed | Interaction Diaphragm and Cardiac Function During Ventilator Weaning NCT03486249 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Sedation and Weaning in Children Requiring Invasive Mechanical Ventilation NCT03673683 | Queen's University, Belfast | N/A |
| Completed | Oxygen Uptake in Weaning of Patients From Prolonged Mechanical Ventilation NCT03433105 | National Taiwan University Hospital | — |
| Completed | Correlation of Two Methods for Cough Peak Flow Measurement in Intubated Patients NCT03357198 | Centre Hospitalier Régional d'Orléans | — |
| Completed | WOB and Paediatric Mechanical Ventilation NCT05254691 | University Medical Center Groningen | N/A |
| Completed | Transcutaneous Carbon Dioxide Pressure (tcPCO2) Monitoring for the Prediction of Extubation Failure in the ICU NCT02894177 | Versailles Hospital | N/A |
| Completed | Analysis on the Fatigue and Electromyographic Activation on the Mechanical Ventilation Weaning NCT07387731 | Federal University of Rio Grande do Sul | N/A |
| Terminated | Breath Synchronized Abdominal Muscle Stimulation to Facilitate Ventilator Weaning: a Pilot Study NCT03019107 | Liberate Medical | — |
| Completed | Handgrip Strength Value in Predicting Mechanical Ventilation Weaning NCT02946502 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Switching Between Invasive and Noninvasive Ventilation to Facilitate Weaning in Difficult-weaning Patients NCT02921347 | Chongqing Medical University | N/A |
| Terminated | Early Tracheotomy for Switching Between Invasive and Noninvasive Ventilation to Facilitate Weaning NCT02921334 | Chongqing Medical University | N/A |
| Completed | Echocardiographic Detection of Extravascular Lung Water Increase During Weaning From Mechanical Ventilation NCT02412202 | University of Thessaly | N/A |
| Unknown | The Predictive Effect of the Inflammatory Response on the Evacuation of Mechanical Ventilation and the Mechani NCT02820090 | Beijing Chao Yang Hospital | — |
| Completed | Role of Lung Ultrasound in Predicting Weaning Outcomes NCT02022839 | Hospital Moinhos de Vento | — |
| Terminated | A Protocol to Wean From Noninvasive Mechanical Ventilation NCT01535755 | Duan jun | N/A |
| Unknown | Acetazolamide Facilitates Ventilator Weaning NCT01131377 | Asan Medical Center | N/A |
| Unknown | Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation NCT00911378 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | Automatic Control of Pressure Support Ventilation in Surgical Intensive Care Units NCT00445289 | University Hospital Schleswig-Holstein | N/A |
| Terminated | Comparative Study of Duration of Respiratory Weaning Between Adaptive Support Ventilation and Succession of Co NCT00313326 | University Hospital, Clermont-Ferrand | Phase 3 |
| Completed | A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitatio NCT00505804 | Austin Health | Phase 2 |
| Completed | Two Cycling Off Modes in Pressure Support: Study of Respiratory Mechanics, Breathing Comfort and Asynchrony Pa NCT00910286 | Hospital de Clinicas de Porto Alegre | N/A |