| Recruiting | A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental NCT07364630 | BioLab Holdings | Phase 4 |
| Recruiting | Tissue Repair Gel in Venous Leg Ulcers in AU/US NCT06707103 | TR Therapeutics | Phase 3 |
| Recruiting | Tissue Repair Gel in Venous Leg Ulcers (US) NCT06707090 | TR Therapeutics | Phase 3 |
| Recruiting | Evaluating the Durability of Closure for Venous Leg Ulcers NCT06697925 | Kerecis Ltd. | — |
| Not Yet Recruiting | Shock Wave Versus Low Level Laser on Chronic Venous Ulcer NCT06756386 | Beni-Suef University | N/A |
| Completed | MicroMatrix® Flex in Tunneling Wounds NCT06629506 | Integra LifeSciences Corporation | N/A |
| Active Not Recruiting | EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds NCT06640985 | ConvaTec Inc. | N/A |
| Recruiting | Fetal Cell Receptors Repertoire NCT06031714 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Evaluation of the Efficacy of Multilayer Compression & UrgoStart Plus NCT06007703 | Gloucestershire Hospitals NHS Foundation Trust | — |
| Unknown | Efficacy of PICO Single-use System in Chronic Ulcers NCT05877378 | University of Castilla-La Mancha | N/A |
| Unknown | Clinical Trial With Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lo NCT05962931 | Andalusian Network for Design and Translation of Advanced Therapies | Phase 1 / Phase 2 |
| Recruiting | Monitoring of Venous Ulcers Using a Bioimpedance Measurement Based Method and System NCT05805137 | CutoSense Oy | N/A |
| Recruiting | The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study NCT05489588 | W.L.Gore & Associates | N/A |
| Completed | Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions NCT05729334 | Skilled Skin S.L. | N/A |
| Active Not Recruiting | The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study NCT05409976 | W.L.Gore & Associates | N/A |
| Terminated | Efficacy Study for Geko Device in VLU Patients (Canada) NCT05057793 | Firstkind Ltd | N/A |
| Unknown | Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring NCT05311124 | Joshua Choo | N/A |
| Unknown | Outcomes of Sclerotherapy of the Ulcer Bed Compared to a Combination of Ablation and Injections NCT05633277 | ProMedica Health System | N/A |
| Unknown | Axial Ablation Versus Terminal Interruption of the Reflux Source NCT04484168 | University College Hospital Galway | N/A |
| Terminated | Debritom - Micro Water Jet Technology and Wound Healing NCT04240574 | Stephanie Wu | N/A |
| Completed | Comparison of the Effectiveness of Two Medical Compression Bandage Application Techniques by Measuring Interfa NCT04046120 | Nantes University Hospital | N/A |
| Terminated | Decellularised Dermis Allograft for the Treatment of Chronic Venous Leg Ulceration NCT04021316 | Imperial College London | N/A |
| Completed | Immediate Versus Early Endovenous Ablation In Venous Ulcer NCT03795064 | Oulu University Hospital | N/A |
| Unknown | Study of Combined Topical Growth Factor and Protease Inhibitor in Chronic Wound Healing NCT02845466 | McMaster University | Phase 3 |
| Terminated | PluroGel on Wounds of Mixed Etiology NCT03275831 | Medline Industries | N/A |
| Withdrawn | Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs NCT02988063 | OhioHealth | Phase 4 |
| Completed | The RESPOND Registry NCT03286452 | Organogenesis | — |
| Completed | Juxta-CuresTM Versus Bandaging for Venous Ulcers NCT02790593 | Colchester Hospital University NHS Foundation Trust | N/A |
| Unknown | Enhanced Ultrasound Treatment of Chronic Wounds With Monitoring of Healing and Quality of Life Outcomes NCT03041844 | Drexel University | N/A |
| Completed | PuraPly™ Antimicrobial Wound Matrix and Wound Management NCT03070938 | Organogenesis | — |
| Unknown | Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers NCT02838784 | Tides Medical | N/A |
| Unknown | TAPIRS Technique Plus Adjustable Compression System in Treatment of Venous Leg Ulcers NCT02798445 | Hospital Occidente de Kennedy | N/A |
| Completed | Low-level Light Therapy on Treatment of Venous Ulcers Assesed by Nursing Outcome Classification (NOC) NCT03229330 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence NCT02626156 | Medical University of South Carolina | Phase 2 |
| Completed | Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ul NCT02395302 | Tactile Medical | N/A |
| Terminated | Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers NCT01853384 | Healthpoint | Phase 3 |
| Completed | Adipose Derived Regenerative Cellular Therapy of Chronic Wounds NCT02092870 | Tower Outpatient Surgical Center | Phase 2 |
| Terminated | ECM and Blood Components for Wound Healing NCT01909908 | Cook Group Incorporated | N/A |
| Completed | The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study NCT01770509 | M.D. Lederman Consulting Ltd | Phase 1 / Phase 2 |
| Terminated | Restore Calcium Alginate Dressing, Silver vs Aquacel Ag in the Treatment of Critically Colonized Venous Leg Ul NCT01396304 | Hollister Wound Care LLC | Phase 4 |
| Completed | Venous Ulcer Treatment With Foam Versus Conservative Treatment NCT01594658 | Hospital Occidente de Kennedy | — |
| Completed | Cell Therapy for Venous Leg Ulcers Pilot Study NCT01750749 | Hospital de Clínicas Dr. Manuel Quintela | Phase 1 |
| Completed | A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers NCT01327937 | Organogenesis | Phase 4 |
| Suspended | Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers NCT00933348 | Phoenix Eagle Company | Phase 2 |
| Terminated | Silica Gel Fiber Wound Dressing for Chronic Venous Leg Ulcers NCT00998673 | Bayer | Phase 2 |
| Completed | A Trial to Assess the Safety and Activity of Nexagon® for the Treatment of Venous Leg Ulcers (The NOVEL Study) NCT00820196 | OcuNexus Therapeutics, Inc. | Phase 2 |
| Completed | Randomized Clinical Trial (RCT) to Compare the Efficacy of Coban 2 Versus SSB in the Treatment of Venous Leg U NCT00558662 | Solventum US LLC | N/A |
| Terminated | Flexitouch Treatment for Venous Ulcers NCT00847002 | Tactile Systems Technology, Inc. | N/A |
| Completed | Wound Healing Effects of HO/03/03 In Patients With Diabetic Neuropathic Plantar and Venous Ulcers, Pilot Study NCT00338923 | HealOr | Phase 1 |
| Completed | Randomized Controlled 8-week Crossover Evaluation of Compression Bandage Systems for Venous Leg Ulcers NCT00301496 | Solventum US LLC | N/A |
| Withdrawn | Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers NCT00273234 | National Healing Corporation | Phase 3 |
| Completed | Preliminary Testing of New Treatment for Chronic Leg Wounds NCT01858272 | University of Pennsylvania | Phase 1 |
| Completed | Community RCT of the Effectiveness of Two Compression Bandaging Technologies NCT00202267 | Queen's University | Phase 2 |
| Completed | Effectiveness of XCell on Autolytic Debridement of Venous Ulcers NCT00446823 | Xylos Corporation | N/A |