Trisomy 21

30 registered clinical trials studyying Trisomy 21 — 4 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples NCT05970965	Assistance Publique - Hôpitaux de Paris	N/A
Enrolling By Invitation	Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adoles NCT06888570	IMDEA Food	—
Active Not Recruiting	Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography NCT06200519	University College Cork	—
Completed	Paternal Age and Fetal Aneuploidy NCT05981521	Clinique Ovo	—
Recruiting	Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia NCT05527652	University of Michigan	N/A
Completed	Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down NCT05307523	University of Washington	N/A
Completed	Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin Pregnancies NCT05004337	Natera, Inc.	—
Unknown	Study of High Risk Non Invasive Prenatal Test Population NCT04737070	Central Hospital, Nancy, France	—
Terminated	Use of Liquid Stable Levothyroxine in Trisomy 21 Pediatric Patients NCT04747275	Children's Mercy Hospital Kansas City	Phase 4
Unknown	Study of Vanadis® NIPT for Non-invasive Prenatal Screening of Trisomies (T21, T18 and T13) NCT03559374	PerkinElmer, Wallac Oy	—
Terminated	Learning by Repetitive Viewing of Peer Modeling Patient Education Videos by Adults With Down Syndrome NCT03551418	Wake Forest University Health Sciences	N/A
Recruiting	The Human Trisome Project NCT02864108	University of Colorado, Denver	—
Completed	Diagnosis Accuracy of Noninvasive Screening by PCR Digital for Down Syndrom NCT02872948	University Hospital, Grenoble	—
Completed	SNP-based Microdeletion and Aneuploidy RegisTry (SMART) NCT02381457	Natera, Inc.	—
Completed	High Risk Multiple Gestation Study NCT02278874	Natera, Inc.	—
Completed	Prenatal Screening for Down Syndrome With DNAFirst NCT01966991	Women and Infants Hospital of Rhode Island	—
Completed	Non-Invasive Chromosomal Evaluation of Trisomy Study NCT02201862	Cindy Cisneros	—
Completed	Study of the Efficacy of New Non-invasive Prenatal Tests for Screening for Fetal Trisomies Using Maternal Bloo NCT01925742	CHU de Quebec-Universite Laval	N/A
Completed	At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurolo NCT01931644	Sanguine Biosciences	—
Unknown	Down Syndrome Screening Based on Dried Blood Spots and Cell-free Fetal DNA NCT01837979	Peking Union Medical College Hospital	—
Completed	Multiple Gestation Study NCT02278536	Natera, Inc.	—
Completed	Down Syndrome Metabolic Health Study NCT01821300	Children's Hospital of Philadelphia	—
Terminated	Non-invasive Screening of Fetal Trisomy 21 by Digital PCR NCT03687866	University Hospital, Caen	—
Completed	Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Matern NCT01852708	Natera, Inc.	—
Completed	Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA NCT02109770	Natera, Inc.	—
Completed	Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells NCT01725438	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Non-invasive Chromosomal Examination of Trisomy Study NCT01511458	Roche Sequencing Solutions	—
Terminated	Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial NCT01545674	Natera, Inc.	—
Completed	Prenatal Test for Fetal Aneuploidy Detection NCT01256606	Roche Sequencing Solutions	—
Completed	A New Prenatal Blood Test for Down Syndrome NCT00877292	Women and Infants Hospital of Rhode Island	—