Trials / Conditions / Treatment Resistant Depression (TRD)

Treatment Resistant Depression (TRD)

26 registered clinical trials studyying Treatment Resistant Depression (TRD) — 20 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Neuronavigated aiTBS for TRD NCT07329153	University of Texas Southwestern Medical Center	N/A
Not Yet Recruiting	Ketogenic Diet and Neuromodulation in Treatment Resistant Depression NCT07376018	Sunnybrook Health Sciences Centre	N/A
Recruiting	Esketamine With or Without Integration Therapy for Treatment-Resistant Depression NCT07369102	University of Puerto Rico	Phase 4
Recruiting	Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression NCT07324070	Charles University, Czech Republic	N/A
Not Yet Recruiting	Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression NCT07247006	University of Rochester	Phase 2
Not Yet Recruiting	Ketamine Biomarker Validation NCT07307768	Soterix Medical	Phase 1
Not Yet Recruiting	Parcel-guided rTMS for Major Depressive Disorder NCT07287839	Soterix Medical	Phase 2
Recruiting	Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat Depression NCT06773949	The Royal Ottawa Mental Health Centre	N/A
Recruiting	Comparison of the Efficacy of Accelerated Intermittent Theta Burst Stimulation and Accelerated Continuous Thet NCT07264452	Ataturk University	N/A
Not Yet Recruiting	Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Pr NCT07210112	Centre Hospitalier St Anne	Phase 2
Recruiting	Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility an NCT07217223	University of California, San Diego	N/A
Not Yet Recruiting	Algorithm Guided Treatment Versus Treatment as Usual (TAU) for Patients With Treatment Resistant Depression NCT07080723	Aalborg University Hospital	Phase 4
Recruiting	Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression NCT07094789	Sunnybrook Health Sciences Centre	N/A
Recruiting	Maintenance TMS in Treatment Resistant Depression NCT06682299	Austin Messner	N/A
Not Yet Recruiting	Comparison of Different Acceleration Modes of Transcranial Magnetic Stimulation NCT06881030	First Affiliated Hospital of Zhejiang University	N/A
Recruiting	Intravenous Ketamine for Treatment-Resistant Depression NCT06668571	Mayo Clinic	Phase 2
Recruiting	Personalized DBS Targeting for Treating Depression NCT06784388	Second Affiliated Hospital, School of Medicine, Zhejiang University	EARLY_Phase 1
Recruiting	TACS on High-inflammatory and Refractory Depression NCT06812923	Tianjin Anding Hospital	N/A
Active Not Recruiting	Accelerated Transcranial Magnetic Stimulation in Treatment-Resistant Depressed Patients NCT06783361	Ataturk University	N/A
Recruiting	Treatment Resistant Depression and Vagus Nerve Stimulation NCT05952674	Assistance Publique - Hôpitaux de Paris	N/A
Recruiting	Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression NCT07146503	Riccardo Guglielmo	—
Unknown	Auditory MMN EEG in TRD in Response to Ketamine NCT05464264	Unity Health Toronto	—
Completed	Risk-Targeted Behavioural Activation for the Management of Treatment-Resistant Depression. NCT06729580	McGill University	N/A
Completed	MBCT and Escitalopram for Treatment-Resistant Depression in Older Adults NCT07077291	Yun Zhang	N/A
Completed	2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and NCT07097025	Dr.Yoav Domany	—
Completed	Optimization of IV Ketamine for Treatment Resistant Depression NCT00768430	Baylor College of Medicine	Phase 2