Trials / Conditions / Transfusion-dependent Beta-Thalassemia

Transfusion-dependent Beta-Thalassemia

19 registered clinical trials studyying Transfusion-dependent Beta-Thalassemia — 12 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With NCT07506863	Agios Pharmaceuticals, Inc.	Phase 3
Enrolling By Invitation	Use of the Hemanext One® Hypoxic Red Blood Cell Storage System for Transfusion in Thalassemia Patients NCT07055503	University Research Institute for the Study of Genetic & Malignant Disorders in Childhood	—
Not Yet Recruiting	A Pilot Study on the Safety and Efficacy of YOLT-204 for Transfusion-Dependent Beta-Thalassemia NCT06678165	First Affiliated Hospital of Guangxi Medical University	EARLY_Phase 1
Completed	Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Tran NCT07370922	Ain Shams University	Phase 2
Not Yet Recruiting	Plasticizer Exposure and Its Consequences on Health NCT06512298	Medical University of Vienna	—
Enrolling By Invitation	Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene Therapy NCT06664541	Georgetown University	—
Recruiting	Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia NCT06606886	Bahria University	Phase 4
Enrolling By Invitation	A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Wh NCT06363760	Editas Medicine, Inc.	—
Recruiting	Β-Thalassemia Treatment with KL003 Cell Injection NCT06280378	Kanglin Biotechnology (Hangzhou) Co., Ltd.	Phase 1 / Phase 2
Recruiting	Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients NCT06219239	Institute of Hematology & Blood Diseases Hospital, China	N/A
Recruiting	Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia NCT07292259	Pakistan Blood and Marrow Transplant (PBMT) Group	Phase 2
Recruiting	Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene The NCT05991336	Institute of Hematology & Blood Diseases Hospital, China	—
Active Not Recruiting	Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalass NCT05860595	Institute of Hematology & Blood Diseases Hospital, China	N/A
Recruiting	A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TD NCT05762510	First Affiliated Hospital of Guangxi Medical University	EARLY_Phase 1
Active Not Recruiting	EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent B NCT05444894	Editas Medicine, Inc.	Phase 1 / Phase 2
Completed	Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients NCT06146478	Blood Care Clinic	Phase 3
Active Not Recruiting	A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or B NCT04770779	Agios Pharmaceuticals, Inc.	Phase 3
Completed	A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta NCT03432364	Sangamo Therapeutics	Phase 1 / Phase 2
Active Not Recruiting	Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Thera NCT02633943	Genetix Biotherapeutics Inc.	—