| Recruiting | Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Contro NCT07203911 | Tobias Todsen | N/A |
| Recruiting | A Study of Tongue Strength and Endurance Using the Iowa Oral Performance Instrument (IOPI) Tongue Strength Tra NCT07124520 | Memorial Sloan Kettering Cancer Center | N/A |
| Recruiting | Arabic PRO Measures for Head and Neck Cancer Radiotherapy. NCT06662929 | King Saud University | — |
| Unknown | Surgical Margin Assessment by 3D Ultrasound NCT05740774 | Rigshospitalet, Denmark | N/A |
| Completed | The Registry of Oncology Outcomes Associated With Testing and Treatment NCT04028479 | Taproot Health | — |
| Terminated | Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers NCT04738786 | Samsung Medical Center | N/A |
| Completed | Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S NCT04430842 | Quadriga Biosciences, Inc. | Phase 1 |
| Withdrawn | Oral Stent Device for Radiation Treatments of Oral Cancers NCT04041141 | Indiana University | — |
| Completed | Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin NCT04059861 | Region Örebro County | N/A |
| Completed | Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Ge NCT03602079 | Klus Pharma Inc. | Phase 1 / Phase 2 |
| Completed | Radiotherapy of Tongue Cancer Using an Intraoral Stent NCT04337853 | Oslo University Hospital | Phase 1 |
| Completed | Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy NCT04126226 | Hospital de Clinicas de Porto Alegre | N/A |
| Suspended | Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer NCT03181035 | Sunnybrook Health Sciences Centre | Phase 1 / Phase 2 |
| Recruiting | Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue NCT02584270 | University of Michigan | N/A |
| Completed | High-activity Natural Killer Immunotherapy for Small Metastases of Tongue Cancer NCT03008330 | Fuda Cancer Hospital, Guangzhou | Phase 1 / Phase 2 |
| Withdrawn | Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcin NCT02295540 | Rutgers, The State University of New Jersey | N/A |
| Terminated | Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer NCT02177838 | Rutgers, The State University of New Jersey | N/A |
| Completed | Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV No NCT02245100 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | — |
| Completed | Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell C NCT02035527 | Ohio State University Comprehensive Cancer Center | Phase 1 |
| Completed | Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoi NCT02123511 | Mayo Clinic | Phase 2 |
| Withdrawn | Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Ra NCT01728480 | Roswell Park Cancer Institute | Phase 1 |
| Withdrawn | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent Oral Cavity or Oropha NCT01718223 | Roswell Park Cancer Institute | N/A |
| Withdrawn | Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal C NCT01953952 | Radiation Therapy Oncology Group | Phase 2 |
| Terminated | Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer NCT01949740 | University of Chicago | — |
| Unknown | Effects of Different General Anesthesia Methods on Immune Responses in Patients Undergoing Surgery for Tongue NCT01854021 | tiejun Zhang | N/A |
| Completed | PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer NCT01816984 | University of Chicago | Phase 1 / Phase 2 |
| Withdrawn | Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiatio NCT01674374 | Roswell Park Cancer Institute | Phase 2 |
| Completed | Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating NCT01847326 | University of Chicago | Phase 1 |
| Completed | 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis NCT01806675 | Sanjiv Sam Gambhir | Phase 1 / Phase 2 |
| Terminated | Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer or Squamous Cell Hea NCT01528137 | Stanford University | Phase 1 |
| Terminated | A Study of Tongue Conservation Surgery for Oral Tongue Cancer NCT03161548 | Taipei Veterans General Hospital, Taiwan | Phase 2 |
| Completed | TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squam NCT01334177 | University of Washington | Phase 1 |
| Withdrawn | Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck C NCT01332279 | Fox Chase Cancer Center | Phase 1 |
| Completed | Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurr NCT01316757 | Fox Chase Cancer Center | Phase 2 |
| Completed | Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab NCT00939627 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental NCT01816841 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cance NCT01637194 | Fox Chase Cancer Center | Phase 1 |
| Terminated | Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous C NCT00906360 | National Cancer Institute (NCI) | Phase 1 |
| Recruiting | Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck NCT01473784 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer. NCT01469429 | Ohio State University Comprehensive Cancer Center | Phase 1 / Phase 2 |
| Completed | Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer NCT00513435 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer NCT00507767 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral NCT01504932 | Ohio State University Comprehensive Cancer Center | N/A |
| Completed | Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Nec NCT00397384 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell NCT00103259 | National Cancer Institute (NCI) | Phase 2 |
| Completed | GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and N NCT00293462 | Marilyn Dodd | Phase 3 |
| Completed | Lapatinib Ditosylate in Treating Patients With Metastatic or Recurrent Head and Neck Cancer NCT00114283 | National Cancer Institute (NCI) | Phase 2 |
| Completed | S0420, Sorafenib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer NCT00096512 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung Can NCT00068497 | National Cancer Institute (NCI) | N/A |
| Completed | Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx NCT00064103 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Ixabepilone in Treating Patients With Metastatic or Recurrent Squamous Cell Cancer of the Head and Neck NCT00033618 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer NCT00049283 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia NCT00330382 | National Cancer Institute (NCI) | Phase 2 |