| Not Yet Recruiting | Rate of Bone Union After Surgery With Stand-alone Fibergraft NCT07199075 | AO Innovation Translation Center | — |
| Recruiting | Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery NCT07218133 | Alexander T. Yahanda | N/A |
| Recruiting | Effect of Magnesium on Neuromonitoring NCT06975072 | University of California, San Francisco | Phase 4 |
| Not Yet Recruiting | Steroids After Spine Fusion Surgery NCT04568837 | Oregon Health and Science University | Phase 4 |
| Enrolling By Invitation | Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE NCT06450834 | University of Maryland, Baltimore | — |
| Recruiting | Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mix NCT04679844 | Kuros Biosurgery AG | N/A |
| Completed | Evaluation of Surgical Treatment of Idiopathic Scoliosis With Vertebral Body Tethering Versus Posterior Spinal NCT07450326 | Istituto Ortopedico Rizzoli | — |
| Withdrawn | Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP NCT06154980 | Corewell Health East | N/A |
| Not Yet Recruiting | Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate th NCT06580379 | Imperial College London | — |
| Enrolling By Invitation | Titanium vs. PEEK Fusion Devices in 1 Level TLIF NCT05691062 | Twin Cities Spine Center | Phase 4 |
| Completed | PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block NCT07245524 | A.O.U. Città della Salute e della Scienza | — |
| Completed | Erector Spinae Plane Block for Cervical Spine Surgery NCT06393530 | Poznan University of Medical Sciences | Phase 4 |
| Enrolling By Invitation | Pain Control After Lumbar Spine Fusion NCT06484192 | Rothman Institute Orthopaedics | Phase 4 |
| Recruiting | MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-le NCT05037968 | Kuros Biosurgery AG | N/A |
| Completed | Pre-operative Risk Assessment Combined With Targeted Intervention in the Chinese Elderly With Spine Surgery NCT06140797 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery NCT05957822 | Konkuk University Medical Center | Phase 4 |
| Completed | Erector Spinae Plane Block in Spine Surgeries for Postoperative Pain NCT06970704 | Ain Shams University | N/A |
| Unknown | Utility of Exparel Based ESP Blocks in Elective Posterior Spine Fusion NCT06107660 | Hartford Hospital | Phase 4 |
| Recruiting | Effect of Ketamine on Intraoperative Motor Evoked Potentials NCT06140927 | University of California, San Francisco | Phase 3 |
| Suspended | Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complicat NCT06102681 | Duzce University | N/A |
| Completed | Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological De NCT06059820 | Sklifosovsky Institute of Emergency Care | — |
| Unknown | Fusion Status After ACDF NCT05986006 | Rothman Institute Orthopaedics | N/A |
| Unknown | Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine S NCT05850468 | Ain Shams University | N/A |
| Recruiting | Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) NCT05367609 | Senthil Sadhasivam | N/A |
| Completed | Fluid Responsiveness in Prone Position NCT05401526 | Istanbul University | — |
| Completed | Long-term Follow-up Motion Analysis of ACD Versus ACDA NCT04545983 | Zuyderland Medisch Centrum | N/A |
| Completed | Analgesic Effects of Low-dose S-ketamine in Major Spine Fusion Surgery NCT04964219 | Peking University First Hospital | Phase 4 |
| Recruiting | The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion NCT05746143 | University of Southern California | Phase 4 |
| Completed | TLIP Block and ESP Block For Perioperative Analgesia In Patients With Lumbar Spine Fusion Surgery NCT06082245 | Hanoi Medical University | N/A |
| Completed | Post Marketing Study of MagnetOs Putty Compared to Local Autograft in Patients Undergoing Posterolateral Lumba NCT04679896 | Kuros Biosurgery AG | N/A |
| Unknown | Clinical Safety and Efficacy of S53P4 Bioactive Glass Putty in Spinal Fusion Surgery NCT05001893 | Bonalive Biomaterials Ltd | — |
| Unknown | The Role of Bone SPECT/CT in Evaluation of Persistent or Recurrent Back Pain Following Spine Surgery NCT04803136 | Assiut University | N/A |
| Completed | The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients NCT04263909 | Brigham and Women's Hospital | Phase 4 |
| Unknown | Anterior Gen Plus Study NCT04629807 | SeaSpine, Inc. | N/A |
| Completed | Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch NCT04379921 | Stanford University | N/A |
| Terminated | Single Position Spine Surgery Registry NCT04839783 | Spine and Scoliosis Research Associates | — |
| Completed | Denosumab Effect on Bone Quality and Function After Lumbar Fusion Surgery NCT05415657 | Shenzhen People's Hospital | N/A |
| Completed | Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion NCT04095624 | Stanford University | N/A |
| Completed | Effect of Introperative Ketamine and Lidocaine Infusion on Postoperative Opioid Consumption in Posterior Spina NCT04711668 | Ataturk University | N/A |
| Terminated | Relieving Acute Pain (RAP) Study: A Pilot Study NCT03426137 | University of Maryland, Baltimore | Phase 2 |
| Terminated | Prospective Study on Ennovate® Pedicle Screw Fixation in Isthmic Spondylolisthesis Patients NCT03507881 | Aesculap AG | — |
| Completed | Pedicle Screw Placement With XVS NCT04682418 | Augmedics | N/A |
| Completed | Postoperative subQ Pain Control for Spinal Fusion Surgery NCT03476811 | University of Arizona | Phase 2 |
| Terminated | Cognitive Impairment Following Elective Spine Surgery NCT03486288 | University Medicine Greifswald | — |
| Completed | Understanding Non-Response in Spine Fusion Surgery NCT02611479 | University of Washington | — |
| Completed | InductOs® in Real World Spine Surgery; A Retrospective, French, Multi-centric, Study NCT02280187 | Medtronic Spinal and Biologics | — |