| Not Yet Recruiting | Feasibility and Acceptability of Mobile Mental Health App for SZ and SZA NCT06474325 | University of Pittsburgh | N/A |
| Not Yet Recruiting | REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health) NCT07006935 | Case Western Reserve University | N/A |
| Recruiting | Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways NCT07469384 | Nathan Kline Institute for Psychiatric Research | N/A |
| Recruiting | Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder NCT07213466 | Mayo Clinic | Phase 4 |
| Recruiting | Visual Perception in Schizophrenia NCT06911931 | University of Rochester | N/A |
| Unknown | Adapted Physical Activity Program for Patients Undergoing Antipsychotic Treatment of a First Episode of Psycho NCT06643871 | Centre Hospitalier St Anne | N/A |
| Recruiting | Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy NCT06529029 | Michigan State University | Phase 2 / Phase 3 |
| Unknown | Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate NCT06340789 | National Cheng-Kung University Hospital | Phase 2 |
| Recruiting | Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia NCT06174116 | University of Massachusetts, Worcester | Phase 4 |
| Active Not Recruiting | Young Adults With Violent Behavior During Early Psychosis (Aim 2) NCT05756855 | Columbia University | N/A |
| Recruiting | Getting Out of the House: Using Behavioral Activation to Increase Community Participation NCT06336616 | Temple University | N/A |
| Unknown | Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in NCT06176456 | Moscow Psychiatric Hospital No. 1 Named after N.A. Alexeev | N/A |
| Completed | Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Di NCT06041646 | BioXcel Therapeutics Inc | Phase 4 |
| Completed | iTEST: Introspective Accuracy as a Novel Target for Functioning in Psychotic Disorders NCT05899348 | University of California, San Diego | N/A |
| Terminated | Accelerated rTMS for Psychomotor Slowing NCT06134661 | University of Bern | N/A |
| Active Not Recruiting | Ketogenic Diet in People With Schizophrenia NCT05968638 | University of Maryland, Baltimore | N/A |
| Completed | Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness NCT05725785 | University of Washington | N/A |
| Recruiting | Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis NCT05973110 | The Royal Ottawa Mental Health Centre | N/A |
| Unknown | Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bip NCT06093451 | Temple University | Phase 4 |
| Recruiting | Critical Time Intervention-Peer Support NCT05945277 | Lisbon Institute of Global Mental Health - LIGMH | N/A |
| Active Not Recruiting | EPI-MINN: Targeting Cognition and Motivation - National NCT05877716 | University of Minnesota | N/A |
| Recruiting | iTBS to Enhance Social Cognition in People With Psychosis NCT06118268 | Northwell Health | N/A |
| Completed | Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation NCT05445466 | Beth Israel Deaconess Medical Center | N/A |
| Suspended | D-serine AudRem: R33 Phase NCT05046353 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | The Efficacy of Neural Stimulation in Individuals With Schizophrenia NCT05746494 | The University of Texas at Dallas | N/A |
| Completed | Remote State Representation in Early Psychosis NCT05538832 | University of Minnesota | EARLY_Phase 1 |
| Completed | CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies NCT05127837 | University of Washington | N/A |
| Enrolling By Invitation | Rituximab Treatment for Psychosis And/or Obsessive Compulsive Disorder with Probable Immune System Involvement NCT04323566 | Uppsala University Hospital | Phase 2 |
| Recruiting | Acetazolamide for Treatment Resistant Schizophrenia NCT04887792 | Vishwajit Nimgaonkar, MD PhD | Phase 1 / Phase 2 |
| Unknown | Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE) NCT04907279 | Otsuka Canada Pharmaceutical Inc. | — |
| Completed | Targeting Individual Alpha Frequencies to Enhance Perceptual Timing NCT04856657 | University of Minnesota | — |
| Completed | Virtual Reality Training for Social Skills in Schizophrenia - Comparison With Cognitive Training NCT04005794 | Vanderbilt University | N/A |
| Recruiting | Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia NCT05343598 | Mclean Hospital | N/A |
| Completed | Brain Stimulation and Cognitive Training - Efficacy NCT05111548 | University of Michigan | N/A |
| Recruiting | Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Di NCT05025605 | BioXcel Therapeutics Inc | Phase 1 |
| Unknown | Virtual Reality Avatar Therapy for People Hearing Voices NCT04099940 | Psychiatric University Hospital, Zurich | N/A |
| Completed | Peripheral Immune System in Individuals With Schizophrenia NCT05109065 | Stanford University | — |
| Completed | Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizoph NCT05130853 | University of Campania Luigi Vanvitelli | N/A |
| Completed | Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagemen NCT04602741 | Centre for Addiction and Mental Health | N/A |
| Unknown | Implementation, Efficacy and Costs of Inpatient Equivalent Home-Treatment in German Mental Health Care NCT04745507 | Vivantes Netzwerk für Gesundheit GmbH | — |
| Completed | In-person vs. Remote Wellness Support NCT04526067 | The University of Texas Health Science Center at San Antonio | N/A |
| Recruiting | Cognitive Training for Emotion Regulation in Psychotic Disorders NCT04414215 | University of Georgia | N/A |
| Terminated | Models of Auditory Hallucination NCT04210557 | Yale University | N/A |
| Completed | Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia NCT04268303 | BioXcel Therapeutics Inc | Phase 3 |
| Completed | Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis NCT04004416 | University of Michigan | Phase 4 |
| Completed | Transcranial Weak Current Stimulation Treatments for Working Memory Dysfunction in Schizophrenia NCT04637724 | Oded Meiron | N/A |
| Completed | Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY) NCT04327843 | Case Western Reserve University | Phase 3 |
| Completed | Financial Incentives to Improve Medication Adherence NCT04191876 | Northwell Health | N/A |
| Unknown | Bazedoxifene -Treatment for Women With Schizophrenia NCT04113993 | The Alfred | Phase 4 |
| Completed | Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders NCT03943537 | Mclean Hospital | Phase 2 |
| Withdrawn | L-arginine Study for Persistent Symptoms of Schizophrenia NCT04054973 | University of Massachusetts, Worcester | Phase 2 |
| Withdrawn | Repetitive Transcranial Magnetic Stimulation (rTMS) Self-Referential Processing (rTMS-SRP) NCT04068857 | Indiana University | N/A |
| Completed | Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia NCT03648268 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Intervention Targeting Motivational Negative Symptoms NCT04325100 | University of Liege | N/A |
| Unknown | DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currentl NCT03881449 | Durham VA Medical Center | Phase 4 |
| Recruiting | Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia NCT03794076 | Vishwajit Nimgaonkar, MD PhD | Phase 1 / Phase 2 |
| Completed | D-serine Augmentation of Neuroplasticity NCT03711500 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Terminated | Telmisartan Pilot Study on Treatment Resistant Schizophrenia NCT03868839 | Xiaoduo Fan | Phase 2 |
| Completed | A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patie NCT03751488 | Luye Pharma Group Ltd. | Phase 1 |
| Completed | A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women NCT03774641 | Johns Hopkins University | — |
| Completed | Brain Stimulation and Cognitive Training NCT03338673 | University of Michigan | N/A |
| Completed | Cognitive Effects of Nimodipine in Patients With Schizophrenia NCT03671525 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness NCT03208036 | VA Office of Research and Development | N/A |
| Completed | Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia NCT03860597 | University of California, San Diego | Phase 4 |
| Completed | Targeting Auditory Hallucinations With Alternating Current Stimulation NCT03221270 | University of North Carolina, Chapel Hill | N/A |
| Terminated | A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders NCT03261817 | University Hospital, Caen | N/A |
| Completed | Levetiracetam in Early Psychosis NCT03129360 | NYU Langone Health | Phase 2 |
| Completed | Confirmatory Efficacy Trial of a Gluten-Free Diet in a Subgroup of Persons With Schizophrenia Who Have High Le NCT03183609 | University of Maryland, Baltimore | N/A |
| Unknown | Financial Incentives to Improve Acceptance of Antipsychotic Injections NCT03192631 | Focus Community Mental Health Team | N/A |
| Completed | Mobile Enhancement of Motivation in Schizophrenia NCT03059771 | Indiana University | N/A |
| Completed | Examining Persistence in Smokers With Schizophrenia NCT03346291 | Rutgers, The State University of New Jersey | N/A |
| Completed | Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)- NCT02658357 | Braeburn Pharmaceuticals | Phase 2 |
| Completed | Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse NCT03558529 | Manchester Academic Health Science Centre | — |
| Completed | Correlation Between Clinical Deterioration in Schizophrenic Patients and Hair Cortisol Levels NCT01754532 | Shalvata Mental Health Center | — |
| Completed | Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders NCT01720316 | Mclean Hospital | Phase 2 |
| Completed | Self-regulation Strategies to Improve Exercise Behavior Among Schizophrenic Patients NCT01547026 | University of Konstanz | N/A |
| Completed | A Shared Decision-making Training for Inpatients With Schizophrenia NCT02349880 | Technical University of Munich | N/A |
| Terminated | Effects of Metformin and Fish Oil on Treatment With Clozapine NCT02140788 | Duke University | Phase 4 |
| Completed | Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis NCT01003132 | University of Glasgow | N/A |
| Completed | Illness Management and Recovery for Veterans With Severe Mental Illness NCT00515671 | VA Office of Research and Development | N/A |
| Completed | Study Investigating the Safety and Tolerability of Multiple Doses of PF-02545920 in Subjects With Schizophreni NCT00463372 | Pfizer | Phase 1 |