| Not Yet Recruiting | What is the Role of the Exposome in Pulmonary Hypertension NCT07172334 | Poitiers University Hospital | — |
| Not Yet Recruiting | SIRIUS - Initial Combination Therapy With an Endothelin Receptor Antagonist, a Phosphodiesterase-5 Inhibitor a NCT07266519 | Philipps University Marburg | Phase 2 |
| Not Yet Recruiting | Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotat NCT07487441 | Franz Rischard, DO | — |
| Not Yet Recruiting | PNEUMOSTEM® for Improving Respiratory Outcomes in Very Premature Infants Diagnosed With Early Pulmonary Arteri NCT07368088 | Samsung Medical Center | Phase 1 |
| Not Yet Recruiting | Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension NCT07453030 | Caio Júlio César dos Santos Fernandes | — |
| Not Yet Recruiting | Patient-Reported Outcomes and Adherence After Transition From Inhaled Iloprost to Oral Selexipag in Pulmonary NCT07356375 | University of Sao Paulo General Hospital | — |
| Not Yet Recruiting | Genetic Hallmarks of Patients With Congenital Portosystemic Shunts and Portopulmonary Hypertension NCT07314814 | Prof. Valérie Mc Lin | — |
| Not Yet Recruiting | Phase 2 Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH) NCT07318597 | Regeneron Pharmaceuticals | Phase 2 |
| Not Yet Recruiting | COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities NCT07245680 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Recruiting | A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension NCT06872112 | Joseph C. Wu | Phase 1 |
| Not Yet Recruiting | Impact of Sotatercept on Pulmonary Artery and Right Ventricle Remodeling Imaging Assessed With 68Ga-FAPI PET/C NCT07357974 | University Hospital, Brest | Phase 1 / Phase 2 |
| Not Yet Recruiting | Information Sources in Pulmonary Hypertension NCT07207525 | University of Sao Paulo General Hospital | — |
| Not Yet Recruiting | Efficacy and Safety of Treprostinil in Intermediate-Risk Pulmonary Arterial Hypertension NCT07177703 | Shanghai Zhongshan Hospital | Phase 2 |
| Recruiting | A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associate NCT07175038 | AllRock Bio, Inc. | Phase 2 |
| Recruiting | Validation of a Patient Knowledge Questionnaire for Pulmonary Hypertension NCT07120789 | University of Sao Paulo General Hospital | N/A |
| Recruiting | The Impact of ERA Switching on Risk Stratification in Pulmonary Arterial Hypertension NCT07013149 | University of Sao Paulo General Hospital | — |
| Not Yet Recruiting | Long-term Survival and Influencing Factors of Patients With Pulmonary Arterial Hypertension and Diabetes NCT07082933 | Xijing Hospital | — |
| Recruiting | PulmonAry hyperteNsion DiagnOsis: a National cohoRt reseArch NCT06998329 | University of Sao Paulo General Hospital | — |
| Withdrawn | A Phase 2 Study of IkT-001Pro in Pulmonary Arterial Hypertension (PAH) NCT06643143 | Inhibikase Therapeutics | Phase 2 |
| Not Yet Recruiting | Ambrisentan for Early Low-Risk Pulmonary Arterial Hypertension NCT06987097 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Recruiting | Comparison of Sequential to Initial Combination Therapy in PAH NCT06968962 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Recruiting | Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate NCT06658522 | Amsterdam UMC, location VUmc | Phase 4 |
| Recruiting | imprOving Adherence to Pulmonary artErial hyperteNsion Treatment With teLemedicIne and patieNt guidaNce NCT06850792 | University of Sao Paulo General Hospital | N/A |
| Completed | Incorporating the Venous Excess Ultrasound Score (VExUS Score) Into Contemporary Haemodynamic Risk Assessment NCT07266012 | Istanbul University - Cerrahpasa | — |
| Recruiting | AIRDROP: Can we Improve Adherence to Inhaled Treatment for Pulmonary Arterial Hypertension? NCT07457762 | University of Sao Paulo General Hospital | N/A |
| Recruiting | PAH Exercise Study NCT06941441 | University of Washington | Phase 3 |
| Recruiting | Home-Based Clinical Management of Cardiac Complications in Systemic Sclerosis NCT06865118 | Oslo University Hospital | — |
| Completed | Bioequivalence Study to Compare Selexipag 400mcg Film Coated Tablets (400 mcg Selexipag) Versus Uptravi® 400mc NCT06932198 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Terminated | A Study of HS135 for the Treatment of Pulmonary Arterial Hypertension in Adults NCT06493461 | 35Pharma Inc | Phase 1 |
| Recruiting | Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension NCT06477640 | University of Rochester | N/A |
| Not Yet Recruiting | Implementing the Wuqinxi on Patients With Pulmonary Arterial Hypertension NCT06454422 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Recruiting | PROOF OF CONCEPT STUDY ON THE EFFICACY OF INHALATORY TARGETED IMATINIB NANOFORMULATIONS IN PULMONARY HYPERTENS NCT06917196 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Recruiting | Study of Intravenous ZMA001 in Healthy Subjects NCT05967299 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 1 |
| Completed | Effects of UE Aerobic Exercise on Exercise Capacity and PA in Patients With Pulmonary Arterial Hypertension. NCT05947240 | Riphah International University | N/A |
| Completed | Safety and Effectiveness of a Virtual Pediatric Cardiac Rehabilitation Program or Telerehabilitation in Childr NCT06819059 | Columbia University | N/A |
| Completed | a Non-interventional Study of Sildenafil in the Treatment of Pulmonary Arterial Hypertension (PAH) in Adults F NCT05546125 | Pfizer Pharmaceuticals Ltd. | — |
| Completed | (RIGHT HEART III Study - Right Ventricular Hemodynamic Evaluation and Response to Treatment) NCT03362047 | University of Giessen | Phase 2 |
| Completed | ALlogeneic Cardiosphere-derived Stem Cells (CDCs) for Pulmonary Hypertension therApy NCT03145298 | Cedars-Sinai Medical Center | Phase 1 |
| Unknown | The PAH Disability and Bothersomeness Questionnaire NCT03235401 | Association de Recherche en Physiopathologie Respiratoire | — |
| Completed | Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension NCT03523910 | University of Wisconsin, Madison | N/A |
| Terminated | Therapy of Pulmonary Arterial Hypertension (PAH) - Treatment With Sildenafil in Eisenmenger Patients NCT00586794 | Competence Network for Congenital Heart Defects | Phase 3 |
| Recruiting | COMPERA / COMPERA-KIDS NCT01347216 | Technische Universität Dresden | — |