| Active Not Recruiting | Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool NCT05706311 | University of Utah | N/A |
| Recruiting | fMRI and Opioid Abstinence NCT06651333 | Yale University | — |
| Recruiting | Opioid/Benzodiazepine Polydrug Abuse: Aim 3 NCT05006079 | Wayne State University | Phase 2 |
| Unknown | A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders. NCT05995873 | MindLight, LLC | N/A |
| Withdrawn | OLP to Manage Pain in TJA: A Feasibility Study NCT04883983 | University of Alabama at Birmingham | EARLY_Phase 1 |
| Recruiting | Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment NCT05711056 | Emory University | N/A |
| Completed | Buprenorphine Induction and Naloxone Distribution Program-Combined With Warm Hand-Off Referral to Continued Tr NCT06087991 | Jerry Cochran | — |
| Terminated | Novel Induction to Buprenorphine/Naloxone NCT05644587 | Bicycle Health | Phase 4 |
| Completed | AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm NCT04758637 | University of Southern California | N/A |
| Completed | Opioid Education in Total Knee Arthroplasty NCT05593341 | Hospital for Special Surgery, New York | N/A |
| Completed | Community Trial in the Cherokee Nation NCT04839978 | Emory University | N/A |
| Unknown | Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction NCT03394911 | Bubba Nicholson | Phase 3 |
| Completed | Ketamine for the Treatment of Opioid Use Disorder and Depression NCT04177706 | Medical University of South Carolina | Phase 2 |
| Withdrawn | Opioids and Smoking Cessation NCT03857139 | University of Houston | Phase 4 |
| Unknown | A Multi-centre Survey on Tramadol Abuse in Singapore NCT04813458 | Singapore General Hospital | — |
| Terminated | Pain Management Following Sinus Surgery NCT03822962 | University of Nebraska | EARLY_Phase 1 |
| Completed | PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers NCT04601506 | University of Minnesota | N/A |
| Completed | PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population NCT04601493 | University of Minnesota | N/A |
| Completed | PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Popula NCT04601480 | University of Minnesota | N/A |
| Completed | Postoperative Opt-In Narcotic Treatment Study NCT04710069 | University of California, Los Angeles | N/A |
| Terminated | The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean P NCT04033562 | WellSpan Health | Phase 4 |
| Completed | Efficacy And Safety Of An Innovative Treatment Of Opiate Use Disorders NCT04340622 | MindLight, LLC | N/A |
| Completed | Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening Tool NCT03936985 | University of Utah | — |
| Terminated | Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy NCT04495374 | Universidade Federal de Alfenas | Phase 4 |
| Recruiting | Neuromodulation and Cognitive Training in Opioid Use Disorder NCT03773523 | University of Minnesota | N/A |
| Terminated | A Multimodal Enhanced Recovery Program in Anorectal Surgery NCT03992079 | Columbia University | N/A |
| Completed | Pain Control Following Sinus Surgery NCT03783702 | Stanford University | Phase 4 |
| Completed | A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Pati NCT03611335 | NYU Langone Health | — |
| Completed | The Navigator Trial NCT03684681 | Rhode Island Hospital | N/A |
| Completed | PCORnet Opioid Surveillance Study NCT03743493 | Louisiana Public Health Institute | — |
| Unknown | Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications NCT03570099 | Region Skane | — |
| Completed | Oral Abuse Potential Study of Nalbuphine NCT04018664 | Trevi Therapeutics | Phase 1 |
| Completed | Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients NCT03377855 | Weill Medical College of Cornell University | N/A |
| Suspended | Opioid Reduction Toolkit Reduces Opioids Prescribed and Consumed NCT05363436 | Thomas Jefferson University | Phase 4 |
| Completed | Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders NCT03241771 | Kaiser Permanente | N/A |
| Completed | Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder NCT03143855 | Virginia Commonwealth University | Phase 1 |
| Completed | Program for Pain & Prescription Opioid Use in Pregnancy NCT02804152 | Medical University of South Carolina | N/A |
| Completed | Implementing Screening for Cannabis and Other Drug Use Disorders in Primary Care: Impact on Diagnosis and Trea NCT06249542 | Kaiser Permanente | N/A |
| Unknown | Mobile Psychosocial Interventions for MMT Clients NCT01632982 | National Development and Research Institutes, Inc. | N/A |
| Completed | Cell Phone Technology Targeting ART Adherence and Drug Use NCT01884233 | University of California, Los Angeles | N/A |
| Completed | Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers NCT01740414 | New York State Psychiatric Institute | Phase 2 |
| Completed | Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of Oxycodone NCT01395784 | New York State Psychiatric Institute | Phase 2 |
| Completed | A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals NCT01136356 | Johns Hopkins University | Phase 1 / Phase 2 |
| Completed | Study of the Relative Abuse Potential of Acurox Tablets in Non-Dependent Recreational Opioid Users NCT01030406 | Acura Pharmaceuticals Inc. | Phase 2 |
| Unknown | Combined Therapy of Methadone and Dextromethrophan NCT01189097 | National Cheng-Kung University Hospital | Phase 3 |
| Completed | Study of the Abuse Liability of Oxycodone HCl/Niacin in Subjects With a History of Opioid Abuse NCT00699010 | Acura Pharmaceuticals Inc. | Phase 2 |
| Completed | The Discriminative Effects of Tramadol in Humans NCT00499746 | National Institute on Drug Abuse (NIDA) | Phase 1 / Phase 2 |