| Recruiting | Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/C NCT06511050 | Icahn School of Medicine at Mount Sinai | Phase 1 / Phase 2 |
| Enrolling By Invitation | A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis NCT06145867 | Quadram Institute Bioscience | N/A |
| Enrolling By Invitation | Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions NCT06257420 | Simmaron Research Inc. | — |
| Recruiting | The Long COVID-19 Wearable Device Study NCT05741112 | Scripps Translational Science Institute | N/A |
| Completed | Effect of Stellate Ganglion Block on ME/CFS NCT05664711 | Neuroversion, Inc. | Phase 1 |
| Unknown | Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome NCT05454683 | Laboratorios Viñas, S.A. | N/A |
| Completed | Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors NCT05196529 | York University | N/A |
| Recruiting | A 3-day Course for CFS/ME NCT05236465 | Norwegian University of Science and Technology | N/A |
| Completed | RESTORE ME -- RCT of Oxaloacetate on Improving Fatigue in ME/CFS NCT05273372 | Terra Biological LLC | N/A |
| Active Not Recruiting | Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other NCT05167227 | Family Health Centers of San Diego | N/A |
| Completed | Clinical Trial to Assess the Improvement of Fatigue, Sleep Problems, Anxiety / Depression, Neurovegetatives Al NCT04301609 | Vitae Health Innovation | N/A |
| Completed | Long-term Sequelae of COVID-19 (Myalgic Encephalomyelitis): An International Cross-Sectional Study NCT05059184 | Alexandria University | — |
| Completed | Cardiovascular Analysis of PEM NCT04740736 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome NCT04622293 | Rochester Center for Behavioral Medicine | Phase 4 |
| Recruiting | Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome NCT04542161 | Weill Medical College of Cornell University | Phase 2 |
| Completed | Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) NCT04741841 | ImmuneBiotech Medical Sweden AB | N/A |
| Withdrawn | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS NCT04100915 | ProgenaBiome | — |
| Completed | The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue NCT03674541 | Brigham and Women's Hospital | Phase 2 |
| Suspended | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease NCT04031469 | ProgenaBiome | — |
| Completed | The Comeback Study NCT03691987 | University Hospital of North Norway | Phase 2 |
| Completed | Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS NCT04026425 | Ithaca College | N/A |
| Completed | Clinical Trial to Investigate CT38 in the Treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome NCT03613129 | LUCINDA BATEMAN, MD | Phase 1 / Phase 2 |
| Unknown | New MRT Imaging Biomarkers and Treatment With Kinetic Oscillatory Stimulation (KOS) in Nasal Cavity for Myalgi NCT03502044 | Karolinska University Hospital | N/A |
| Completed | Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME S NCT05128292 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) NCT03254823 | University of East Anglia | — |
| Unknown | Complex Chronic Diseases Program Data Registry NCT03409653 | BC Women's Hospital & Health Centre | — |
| Completed | Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) NCT03000777 | Laboratorios Viñas, S.A. | N/A |
| Unknown | Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome P NCT02854683 | New York Medical College | Phase 1 |
| Completed | Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy NCT02970240 | University of Oslo | — |
| Terminated | Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome NCT01730495 | Haukeland University Hospital | Phase 2 |
| Completed | B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome NCT01156909 | Haukeland University Hospital | Phase 2 |
| Terminated | B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Very Severe Chronic Fatigue Syndrome NCT01156922 | Haukeland University Hospital | Phase 2 |
| Completed | The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial NCT01040429 | Oslo University Hospital | Phase 2 |
| Completed | Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis NCT00920777 | Norwegian University of Science and Technology | N/A |
| Terminated | Pilot Study of Alternative Treatments of Unexplained Chronic Fatigue NCT00983502 | University of Utah | — |
| Completed | The Study of the Safety and Efficacy of Ampligen in Chronic Fatigue Syndrome NCT00215800 | AIM ImmunoTech Inc. | Phase 3 |