| Active Not Recruiting | The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgu NCT07366723 | Centro Cardiologico Monzino | N/A |
| Not Yet Recruiting | Korea VHD Echo Study: Surveillance of Aortic, Mitral & Tricuspid Patients - Insights From Real-world Practice NCT07068633 | Yonsei University | — |
| Recruiting | AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D Ultrasound NCT07384871 | IRCCS Policlinico S. Donato | — |
| Not Yet Recruiting | A Study of Mitral Annular Disjunction in Mitral Valve Prolapse Patients and Arrhythmia Risk NCT06741709 | Assiut University | — |
| Recruiting | Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring NCT06378996 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Recruiting | Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery NCT06255457 | Karolinska Institutet | — |
| Recruiting | PRIMARY Ancillary Substudy NCT07103733 | Annetine Gelijns | N/A |
| Recruiting | Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse NCT06738537 | Northwell Health | — |
| Recruiting | Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse NCT06341166 | Centro Cardiologico Monzino | — |
| Recruiting | Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in NCT05631730 | Oslo University Hospital | Phase 3 |
| Unknown | European FIH Study - NeoChord Transcatheter Mitral Repair System for Symptomatic Mitral Regurgitation NCT05425628 | NeoChord | N/A |
| Recruiting | STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2 NCT04852731 | Central Hospital, Nancy, France | N/A |
| Unknown | Erector Spinae Plane Block for Minimally Invasive Mitral Valve Surgery NCT04770961 | University of California, San Francisco | N/A |
| Unknown | Mitral Valve Prolapse, Arrhythmias and Mitral Valve Surgery NCT05562804 | Ospedale San Raffaele | — |
| Unknown | Neochordae Technique in Mitral Valve Repair NCT04299334 | National Heart Institute, Egypt | Phase 1 |
| Recruiting | Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System NCT04190602 | NeoChord | — |
| Unknown | Patient Specific Mitral Valve Modeling for Surgical Planning and Training NCT03609931 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function NCT03470155 | Institut für Pharmakologie und Präventive Medizin | — |
| Unknown | Primary Mitral Regurgitation Repair NCT04067635 | Eric Y. Yang, MD PhD | — |
| Unknown | Using Pulse Counter Vigileo-Flotrac System in Transapical Off-pump Minimally Invasive Mitral Valve Repair NCT03506217 | Sakarya University | — |
| Terminated | Safety and Performance Study of the Harpoon Mitral Valve Repair System NCT03285724 | Edwards Lifesciences | N/A |
| Completed | Myocardial Characterization of Arrhythmogenic Mitral Valve Prolapse (STAMP: STretch and Myocardial Characteriz NCT02879825 | Central Hospital, Nancy, France | N/A |
| Completed | CE Mark Study for the Harpoon Medical Device NCT02768870 | Edwards Lifesciences | N/A |
| Unknown | The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2 NCT02552771 | Unity Health Toronto | N/A |
| Completed | CE Mark Study for the Harpoon Medical Device in Poland NCT02432196 | Edwards Lifesciences | N/A |
| Unknown | Exercise Capacity Evaluation in Patients With Non-rheumatic Mitral Valve Prolapse (MVP) NCT02499419 | Rambam Health Care Campus | — |
| Completed | Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) NCT02771275 | Edwards Lifesciences | N/A |
| Completed | Myocardial Protection in Minimally Invasive Mitral Valve Surgery NCT04231903 | University of Turin, Italy | — |
| Completed | Automated Algorithm Based Analysis of Phonocardiograms of Newborns NCT02105480 | CSD Labs GmbH | — |
| Completed | Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics NCT02512341 | CSD Labs GmbH | — |
| Recruiting | Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty NCT03113552 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | St. Jude Medical Percutaneous Mitral Valve Repair Study NCT01500148 | Abbott Medical Devices | Phase 1 |
| Unknown | Genetic and Phenotypic Characteristics of Mitral Valve Prolapse NCT03884426 | Nantes University Hospital | — |
| Completed | Mitral Valve Prolapse (MVP) - France Study NCT00799565 | French Cardiology Society | N/A |
| Completed | Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000 NCT00665301 | Woolsthorpe Technologies, LLC | — |
| Unknown | Genetic Basis of Mitral Valve Prolapse NCT01719211 | Massachusetts General Hospital | — |