| Not Yet Recruiting | ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral NCT06167213 | Edwards Lifesciences | N/A |
| Recruiting | Abbott Cephea Mitral Valve Disease Registry NCT07069673 | Abbott Medical Devices | — |
| Recruiting | Early Feasibility Study of Surgical Implantation of a Polymer Prosthetic Mitral and Aortic Valve NCT07097740 | Mitrassist Lifesciences Limited Co., Ltd. | N/A |
| Recruiting | Cephea South America Feasibility Study NCT07244939 | Abbott Medical Devices | N/A |
| Recruiting | Prospective Multicenter Registry of Patients With Mitral Stenosis Undergoing Percutaneous Mitral Balloon Commi NCT07175532 | Asan Medical Center | — |
| Recruiting | Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis NCT07394998 | Gazi University | — |
| Not Yet Recruiting | Mild ANH on Pre-bypass Coagulation Function During Cardiac Surgery NCT06664320 | Konkuk University Medical Center | N/A |
| Not Yet Recruiting | Impact of Percutaneous Transvenous Mitral Commissurotomy on The Left Atrial Appendage Function in Patients Wit NCT06340997 | Assiut University | N/A |
| Recruiting | Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients NCT06377449 | Saint Petersburg State University, Russia | N/A |
| Unknown | Assessment of Right Ventricular Function in Patients With Severe Mitral Stenosis Before and After Balloon Mitr NCT06067815 | Assiut University | — |
| Unknown | The China Mviv Registry NCT05925335 | Xiamen Cardiovascular Hospital, Xiamen University | N/A |
| Unknown | Clinical Investigation for the Foldax Tria Mitral Valve- India NCT06191718 | Foldax, Inc | N/A |
| Completed | Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm NCT06371222 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 4 |
| Active Not Recruiting | Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve NCT05526560 | Edwards Lifesciences | — |
| Unknown | Dapagliflozin Effect on Rheumatic Mitral Stenosis NCT05618223 | Universitas Sebelas Maret | Phase 3 |
| Recruiting | Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry NCT05625607 | Medical University of Warsaw | — |
| Unknown | Left Atrial Appendage (LAA) Clot With Severe Mitral Stenosis NCT05186649 | University of Karachi | — |
| Recruiting | The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves). NCT04408430 | Mayra Guerrero | N/A |
| Active Not Recruiting | Dabigatran for Mitral Stenosis Atrial Fibrillation NCT04045093 | The University of Hong Kong | Phase 4 |
| Unknown | The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients NCT03991910 | Indonesia University | Phase 3 |
| Terminated | RIvoraxaban in Mitral Stenosis NCT03926156 | Rajaie Cardiovascular Medical and Research Center | Phase 3 |
| Completed | French National Observatory of Percutaneous Mitral Commissurotomy NCT02783248 | French Cardiology Society | — |
| Completed | Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery NCT02502448 | Konkuk University Medical Center | N/A |
| Active Not Recruiting | ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New T NCT01757665 | Edwards Lifesciences | N/A |
| Completed | Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region NCT02188862 | University of Oxford | — |
| Completed | Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery NCT02831270 | Konkuk University Medical Center | — |
| Unknown | Bosentan for Severe Mitral Valve Dysfunction NCT01270750 | General Hospital of Chalkida | Phase 1 / Phase 2 |
| Completed | Beating Versus Arrested Heart for Mitral Valve Replacement NCT01641614 | Federal University of Bahia | Phase 4 |
| Completed | Effect of Ivabradine on Heart Rate & Effort Tolerance in Mitral Stenosis in Sinus Rhythm NCT01022463 | Govind Ballabh Pant Hospital | Phase 3 |
| Completed | Epidemiology and Long-term Outcome of Patients With VHD NCT04527367 | Medical University of Bialystok | — |