| Not Yet Recruiting | App-Based Migraine Treatment: The Health enSuite Study NCT06797076 | IWK Health Centre | N/A |
| Not Yet Recruiting | Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38 NCT07342296 | Danish Headache Center | N/A |
| Withdrawn | The Sequestration of Holistic Stress Management Techniques for Adults NCT06098755 | Goddess Zena I. Jones | N/A |
| Recruiting | Neurogenetic And Hemodynamic Of Migraine Aura And Pfo NCT07349004 | Azienda Usl di Bologna | — |
| Recruiting | Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide NCT07021859 | Danish Headache Center | N/A |
| Withdrawn | Healthy Living Partnerships for Veterans With Migraine NCT04373330 | Wake Forest University Health Sciences | N/A |
| Recruiting | Trial Designs for Evaluating Migraine Treatment NCT06617832 | University of Aarhus | N/A |
| Active Not Recruiting | Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine P NCT06414044 | University of Florence | — |
| Recruiting | RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment NCT06409832 | University of Florence | — |
| Recruiting | Effectiveness and Tolerability of Eptinezumab NCT06409845 | University of Florence | — |
| Unknown | Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP) NCT06267664 | Hospital Clínico Universitario de Valladolid | — |
| Completed | Mi-Helper Transnasal Cooling for Acute Treatment of Migraine NCT06051604 | CoolTech LLC | N/A |
| Unknown | Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine NCT05416476 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Recruiting | Migraine Attack Pain Phase Prediction Study NCT06459635 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Terminated | PArtial REbreathing for Migraine With Aura 1 NCT05546385 | Rehaler | N/A |
| Completed | Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatme NCT06023953 | Theranica | — |
| Recruiting | Gepant treAtments: EffectIveNess and tolERability (GAINER) NCT05903027 | University of Florence | — |
| Completed | Ditan Acute tReatments: Effectiveness and Tolerability (DART) NCT05903040 | University of Florence | — |
| Recruiting | TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME） NCT05484349 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Unknown | The FreMRI Study: Advanced MRI on Migraine Patients Treated With Fremanezumab NCT06244823 | Hospital Clínico Universitario de Valladolid | Phase 4 |
| Unknown | Tailored Digital Treatment for Migraine NCT05617339 | Vastra Gotaland Region | N/A |
| Recruiting | Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification NCT06674772 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study NCT05281770 | Austrian Migraine Registry Collaboration | — |
| Unknown | The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. NCT05565001 | Danish Headache Center | N/A |
| Terminated | Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine NCT05214001 | Messoud Ashina, MD | Phase 4 |
| Terminated | Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine NCT05211154 | Danish Headache Center | Phase 4 |
| Unknown | Optical Coherence Tomography Findings in Migraine NCT05332431 | Assiut University | — |
| Terminated | Transnasal Cooling for Migraine NCT04936061 | CoolTech LLC | N/A |
| Terminated | Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room NCT04726592 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Digital Treatment for Migraines - a Feasibility Study NCT05018572 | Vastra Gotaland Region | N/A |
| Completed | A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment o NCT04940390 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Recruiting | Mind Body Balance for Pediatric Migraine NCT04715685 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects NCT05337254 | Satsuma Pharmaceuticals, Inc. | Phase 1 |
| Completed | A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine NCT04406649 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Recruiting | Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on the Efficacy of Amiloride in the Proph NCT04063540 | Centre Hospitalier Universitaire de Nice | Phase 2 |
| Unknown | The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Propert NCT04452929 | Danish Headache Center | N/A |
| Completed | A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine NCT03901482 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Completed | The Effect of Connective Tissue Massage in Patients With Migraine NCT04171362 | Ankara Yildirim Beyazıt University | N/A |
| Completed | A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy NCT03874832 | Satsuma Pharmaceuticals, Inc. | Phase 1 |
| Completed | Can DFN-15 Terminate Migraine With Allodynia? NCT03472378 | Hartford Hospital | Phase 2 |
| Completed | pLatelEts And MigRaine iN patEnt foRamen Ovale NCT03521193 | Centro Cardiologico Monzino | N/A |
| Active Not Recruiting | Sensitivity to Acute Cerebral Ischemia in Migrainers NCT03301441 | University Hospital, Montpellier | — |
| Completed | Evaluation of a Novel Device for Treatment of Migraine Headache NCT03361423 | Theranica | N/A |
| Completed | Integrative Migraine Pain Alleviation Through Chiropractic Therapy NCT03177616 | Harvard University Faculty of Medicine | N/A |
| Completed | Continue or Stop Applying Wet Cupping (Al-Hijamah) in Migraine NCT03479060 | Karabuk University | N/A |
| Completed | Partial Rebreathing in the Treatment of Migraine With Aura NCT03472417 | University of Aarhus | N/A |
| Unknown | Endothelin-1 as a Potential Trigger of Migraine Aura NCT02906085 | Glostrup University Hospital, Copenhagen | N/A |
| Unknown | Pharmacologically Triggered Migraine Without Aura and Neuroimaging NCT03143465 | Danish Headache Center | N/A |
| Completed | Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura. NCT02708797 | University Hospital, Toulouse | N/A |
| Completed | Mindfulness for Adolescents for CM and HFEM NCT04968093 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | N/A |
| Completed | Induction of Migraine Aura With Sildenafil NCT02795351 | Herlev Hospital | EARLY_Phase 1 |
| Completed | Induction of Migraine Aura With Cilostazol NCT02253004 | Herlev Hospital | EARLY_Phase 1 |
| Completed | IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Head NCT02115269 | Abbott | — |
| Completed | Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine NCT01741714 | University Hospital, Akershus | N/A |
| Completed | Impact of a Nurse for Migraine Management: the IMPACT Project NCT01804517 | Notre-Dame Hospital, Montreal, Quebec, Canada | — |
| Completed | Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment NCT01814189 | Shahid Beheshti University of Medical Sciences | Phase 3 |
| Unknown | Investigation of the Blood-brain and Blood-dura Barrier Durin Migraine Attacks Using MRI NCT02202486 | Glostrup University Hospital, Copenhagen | — |
| Withdrawn | The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine NCT01653522 | The Cleveland Clinic | N/A |
| Completed | Impact of tDCS on Cerebral Autoregulation NCT01865604 | Charite University, Berlin, Germany | N/A |
| Completed | Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department NCT01596166 | University of Alberta | Phase 4 |
| Unknown | Preventive Treatment of Episodic and Chronic Migraine NCT01319825 | California Medical Clinic for Headache | Phase 4 |
| Completed | Women With Migraine With Aura Neuroimaging Study NCT02047695 | Odense University Hospital | — |
| Unknown | Functional MRI and MRA in Migraine With Aura NCT01388894 | Glostrup University Hospital, Copenhagen | — |
| Completed | Migraine and Endothelial Dysfunction NCT01388699 | Charite University, Berlin, Germany | — |
| Unknown | Efficacy of Sumatriptan With Naprosyn in Migraine With Aura NCT00893594 | Dent Neurologic Institute | N/A |
| Completed | Oxygenation and Perfusion in Patients With Acute Migraine Attacks NCT03536936 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP) NCT01257880 | Swedish Medical Center | — |
| Completed | Study of NXN 188 for the Treatment of Migraine With Aura NCT00920686 | NeurAxon Inc. | Phase 2 |
| Unknown | Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura NCT00877838 | Danish Headache Center | Phase 2 |
| Completed | Candesartan Versus Propranolol for Migraine Prevention NCT00884663 | Norwegian University of Science and Technology | Phase 2 / Phase 3 |
| Completed | Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA) NCT00687947 | Danish Headache Center | N/A |
| Terminated | A Study of a Melatonin Receptor Agonist to Prevent Migraine NCT00739024 | Swedish Medical Center | Phase 2 |
| Completed | Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache NCT00534560 | Minster Research Ltd | Phase 2 |
| Unknown | Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine NCT00285402 | Ariston Pharmaceuticals, Inc. | Phase 2 |
| Completed | Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache NCT00471952 | Diamond Headache Clinic | Phase 3 |
| Completed | Efficacy and Safety of TMS for the Preemptive Treatment of Migraine With Aura NCT00449540 | Neuralieve | Phase 3 |
| Terminated | PRIMA PFO Migraine Trial NCT00505570 | Abbott Medical Devices | Phase 2 |
| Completed | Tonabersat in the Prophylaxis of Migraine With Aura NCT00332007 | Minster Research Ltd | Phase 2 |
| Completed | Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache NCT00311662 | Minster Research Ltd | Phase 2 |
| Completed | Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migra NCT00123201 | Solvay Pharmaceuticals | Phase 2 |
| Completed | Evaluation of the Efficacy and Safety of Laxymig® as Prophylactic Treatment in Patients With Migraine NCT00334178 | Lotus Pharmaceutical | Phase 3 |
| Completed | Eletriptan Provides Consistent Migraine Relief: Results Of A Within-Patient Multiple-Dose Study NCT01859481 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |