| Recruiting | Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Res NCT07537998 | Pei-Rong Ding | Phase 2 / Phase 3 |
| Recruiting | A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in R NCT06424522 | Ohio State University Comprehensive Cancer Center | N/A |
| Not Yet Recruiting | The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress NCT07253298 | National Taiwan University Hospital | N/A |
| Not Yet Recruiting | Transanal Irrigation for the Management of Early Low Anterior Resection Syndrome (LARS) NCT07219745 | Case Comprehensive Cancer Center | N/A |
| Not Yet Recruiting | Retrograde and Antegrade Enema for Prevention of LARS After LAR: a Randomized Controlled Trial NCT06717854 | Sichuan Cancer Hospital and Research Institute | N/A |
| Not Yet Recruiting | Transanal Irrigation for Low Anterior Resection Syndrome NCT06796296 | Seoul National University Hospital | N/A |
| Recruiting | Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. NCT06758830 | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | Phase 2 / Phase 3 |
| Not Yet Recruiting | Fecal Microbiota Transplantation in the Treatment of Major LARS NCT06475430 | Peking University People's Hospital | N/A |
| Active Not Recruiting | Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients. NCT06724198 | Sykehuset Telemark | N/A |
| Not Yet Recruiting | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Tria NCT06524362 | GEM Hospital & Research Center | N/A |
| Recruiting | The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection NCT06222255 | Seoul National University Hospital | N/A |
| Unknown | Effect of Gelsectan® in the Treatment of Low Anterior Resection Syndrome NCT06162143 | Istituto Clinico Humanitas | — |
| Recruiting | Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer NCT05943444 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Unknown | Transanal Irrigation - Best Treatment Possibility for Low Anterior Resection Syndrome? Multicenter, Randomized NCT05920681 | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | N/A |
| Recruiting | Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled Trial NCT05682157 | Hadassah Medical Organization | N/A |
| Active Not Recruiting | Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer. NCT06601985 | Shanghai 10th People's Hospital | — |
| Completed | Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (N NCT05605600 | Cardiff and Vale University Health Board | — |
| Active Not Recruiting | Transanal Irrigation for Low Anterior Resection Syndrome. NCT05245331 | Hospital Universitari de Bellvitge | N/A |
| Unknown | Low Anterior Resection Syndrome After Rectum Resection for Rectal Carcinoma. NCT05506111 | Paracelsus Medical University | — |
| Recruiting | Assessment of Quality of Life After Low Anterior Resection During Cytoreductive Surgery for Advanced Ovarian C NCT05431530 | Seoul National University Hospital | — |
| Recruiting | Impact of Early Postoperative Treatment With Posterior Tibial Nerve Stimulation on the Incidence and Duration NCT05368168 | Innovacion en Cirugía Vigo | N/A |
| Completed | Effect of Exercise on Bowel Function in Colorectal Cancer Survivors NCT05420870 | Yonsei University | N/A |
| Unknown | Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study NCT05319054 | Cardiff and Vale University Health Board | N/A |
| Completed | Evaluation of a Decision Aid Tool in Rectal Cancer patiënts NCT04938336 | University Hospital, Ghent | — |
| Unknown | Rectal Cancer Shared Care NCT04966819 | Jewish General Hospital | N/A |
| Completed | Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advan NCT06271629 | Seoul National University Hospital | — |
| Active Not Recruiting | Transanal Irrigation for the Management of LARS NCT05007015 | Jewish General Hospital | N/A |
| Completed | Paula Method of Exercises in Patients With LARS Syndrome NCT05016583 | Hadassah Medical Organization | N/A |
| Unknown | The Effect of Melatonin in Patients With Low Anterior Resection Syndrome NCT05042700 | Ismail Gögenur | Phase 2 |
| Recruiting | The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the NCT06569966 | The Affiliated Hospital of Qingdao University | N/A |
| Unknown | Transanal Irrigation to Prevent Major Low Anterior Resection Syndrome NCT04758195 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Unknown | Anal Dilatation Plus Probiotics Before Ileostomy Reduction for Low Anterior Resection Syndrome NCT04688242 | Sixth Affiliated Hospital, Sun Yat-sen University | Phase 2 |
| Unknown | Feasibility and Impact of a Prehabilitation and Rehabilitation Program for the Continuity of Care in Severe Lo NCT04612569 | Hospital Donostia | — |
| Completed | Interactive Online Informational and Peer Support App for Patients with Low Anterior Resection Syndrome NCT04469426 | Jewish General Hospital | N/A |
| Completed | Development and Validation of The Post-RT LARS Prediction Model (PORTLARS) NCT05129215 | Sixth Affiliated Hospital, Sun Yat-sen University | — |
| Completed | Randomized Clinical Trial on Transanal Irrigation NCT04586634 | Coloplast A/S | N/A |
| Withdrawn | Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Ca NCT03257332 | Slagelse Hospital | — |
| Recruiting | Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome NCT04087421 | University of Aarhus | Phase 3 |
| Completed | Impact of a Patient-Centered Program for Low Anterior Resection Syndrome a Multicenter Randomized Controlled T NCT03828318 | Jewish General Hospital | N/A |
| Unknown | International Low Anterior Resection Score Evaluation NCT04040842 | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | — |
| Unknown | The Effect of Different Reconstruction Methods on Anterior Resection Syndrome NCT04023448 | Third Affiliated Hospital, Sun Yat-Sen University | N/A |
| Terminated | Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Lo NCT04066894 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Acupuncture in Low Anterior Resection Syndrome Treatment NCT03916549 | National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos | Phase 1 |
| Completed | Contributing Factors to Anterior Resection Syndrome and Its Impact on Quality of Life: A Retrospective Cohort NCT04114591 | University of Malta | — |
| Completed | Effectiveness of Sacral Neuromodulation in Low Anterior Resection Syndrome NCT03598231 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | Bowel Dysfunction 3 Years After Anterior Resection a in a Swedish National Cohort NCT04591821 | Region Skane | — |
| Completed | Effect of Treatment of Low Anterior Resection Syndrome After Rectal Cancer Surgery NCT03215017 | Mirna Abraham-Nordling | N/A |
| Completed | Rectal Cancer Survivorship: Impact of Low Anterior Resection Syndrome (LARS) on the Quality of Life NCT06059170 | University Hospital, Ghent | N/A |
| Completed | Experiences and Needs of Patients, Their Informal Caregiver and Healthcare Professionals Regarding LARS NCT04896879 | University Hospital, Ghent | — |
| Completed | Bowel Dysfunction After Rectal Cancer Treatment NCT05020132 | Consorci Sanitari de Terrassa | — |
| Unknown | Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surg NCT02177084 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | Phase 2 |
| Completed | The Value of Botox-A for Management of Low Anterior Resection Syndrome NCT01589471 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Completed | LARS in Ovarian Cancer Patients NCT04279080 | Medical University of Vienna | — |