Clinical Trials Directory

Trials / Conditions / Locally Advanced Solid Tumor

Locally Advanced Solid Tumor

46 registered clinical trials studyying Locally Advanced Solid Tumor17 currently recruiting.

StatusTrialSponsorPhase
Not Yet Recruiting5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors
NCT07404332
Mohammed MilhemPhase 1
RecruitingA Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Ac
NCT07213817
IpsenPhase 1 / Phase 2
RecruitingClinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors
NCT06975410
Yuhan CorporationPhase 1 / Phase 2
RecruitingPhase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid Tumors
NCT06658353
Jiangsu vcare pharmaceutical technology co., LTDPhase 3
RecruitingCD8 PET Imaging in Metastatic Solid Tumours
NCT06534190
University Medical Center GroningenPhase 2
RecruitingTopical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Patients With Solid Tumors
NCT06358677
University of UtahPhase 2
RecruitingIBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors
NCT06349408
Innovent Biologics (Suzhou) Co. Ltd.Phase 1
TerminatedA Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metasta
NCT06630247
ExelixisPhase 1
RecruitingACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor
NCT06415487
Acepodia Biotech, Inc.Phase 1
RecruitingLattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
NCT06416007
University of CincinnatiPhase 2
RecruitingA Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
NCT06521554
Nuvalent Inc.Phase 1
RecruitingA Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer
NCT06184035
Spago Nanomedical ABPhase 1 / Phase 2
Active Not RecruitingStudy of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring
NCT05919537
Hummingbird BiosciencePhase 1
RecruitingA Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Seque
NCT06028724
Centro di Riferimento Oncologico - Aviano
RecruitingSafety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors
NCT05732831
Tango Therapeutics, Inc.Phase 1 / Phase 2
RecruitingFOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264
Parabilis Medicines, Inc.Phase 1 / Phase 2
UnknownA Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations
NCT05769075
TYK Medicines, IncPhase 1
Active Not RecruitingA Study of ES014 in Patients With Locally Advanced or Metastatic Solid Tumours
NCT05717348
Elpiscience (Suzhou) Biopharma, Ltd.Phase 1
Active Not RecruitingA First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors
NCT05731271
Suzhou Transcenta Therapeutics Co., Ltd.Phase 1 / Phase 2
RecruitingA Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and
NCT05378425
Nectin Therapeutics LtdPhase 1
WithdrawnA Phase 1 Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Repotrectinib in Advance
NCT05828277
Turning Point Therapeutics, Inc.Phase 1
RecruitingA Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrange
NCT05384626
Nuvalent Inc.Phase 1 / Phase 2
UnknownA Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
NCT05268666
Jubilant Therapeutics Inc.Phase 1 / Phase 2
UnknownSOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positiv
NCT05218148
Aiping ZhouPhase 2
TerminatedSafety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors
NCT05275478
Tango Therapeutics, Inc.Phase 1 / Phase 2
TerminatedNiraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors
NCT05169437
Tempus AIPhase 2
Active Not RecruitingA Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab
NCT05081609
Ascendis Pharma Oncology Division A/SPhase 1 / Phase 2
RecruitingA Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearra
NCT05118789
Nuvalent Inc.Phase 1 / Phase 2
CompletedA Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumours
NCT04914117
RemeGen Co., Ltd.Phase 1
UnknownA Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancie
NCT05028478
Curon Biopharmaceutical (Australia) Co Pty LtdPhase 1 / Phase 2
CompletedDouble/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors
NCT04975958
Adlai Nortye Biopharma Co., Ltd.Phase 1
CompletedTrial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients
NCT05002140
XRad Therapeutics IncPhase 1
TerminatedA Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid
NCT04799054
Ascendis Pharma Oncology Division A/SPhase 1 / Phase 2
CompletedA Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic T
NCT04814667
Centre Leon Berard
UnknownThe Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors
NCT04614740
Jiangsu vcare pharmaceutical technology co., LTDPhase 1 / Phase 2
CompletedAdvanced Lung Tumor Treated by Osimertinib Plus Anlotinib
NCT04770688
Shanghai Chest HospitalPhase 1 / Phase 2
TerminatedStudy of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
NCT04383210
Elevation OncologyPhase 2
TerminatedA Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic
NCT04260802
Ocellaris Pharma, Inc.Phase 1 / Phase 2
CompletedACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors
NCT04319757
Acepodia Biotech, Inc.Phase 1
CompletedA Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Adva
NCT04200963
Ikena OncologyPhase 1
TerminatedPhase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors
NCT04084366
OBI Pharma, IncPhase 1 / Phase 2
UnknownEfficacy of Perioperative Chemotherapy Plus PD-1 Antibody in the Locally Advanced Gastric Cancer
NCT04250948
Sun Yat-sen UniversityPhase 2
CompletedQUILT-3.064: PD-L1 t-haNK In Subjects With Locally Advanced Or Metastatic Solid Cancers
NCT04050709
ImmunityBio, Inc.Phase 1
CompletedStudy of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors
NCT03881488
Compass TherapeuticsPhase 1
UnknownHM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic So
NCT03284502
Hanmi Pharmaceutical Company LimitedPhase 1
CompletedTrial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT01390818
EMD SeronoPhase 1