Trials / Conditions / Locally Advanced Rectal Cancer (LARC)

Locally Advanced Rectal Cancer (LARC)

19 registered clinical trials studyying Locally Advanced Rectal Cancer (LARC) — 14 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Evaluating the Impact of GLP-1 Receptor Agonists With Total Neoadjuvant Therapy in Rectal Cancer NCT07314528	St. James's Hospital, Ireland	Phase 2
Recruiting	Application and Exploration of Personalized ctDNA-MRD Detection Technology in Predicting the Efficacy of Neoad NCT07393048	Beijing Friendship Hospital	—
Not Yet Recruiting	XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS NCT07381777	Gruppo Oncologico Italiano di Ricerca Clinica	Phase 2
Not Yet Recruiting	Phase II Basket Trial: Zanidatamab Plus Tislelizumab in HER2-Positive GI Tumors (UNION-HER2-BASKET) NCT07243938	Tao Zhang	Phase 2
Recruiting	A Single-center, Phase II Study on Efficacy & Safety of SCRT+CAPOX+Serplulimab+Bevacizumab for MSS Rectal Canc NCT07347951	First Affiliated Hospital of Wenzhou Medical University	Phase 2
Not Yet Recruiting	QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer NCT07175636	Sun Yat-sen University	Phase 2
Recruiting	Real-world Efficacy and Safety of Neoadjuvant Dostarlimab in Patients With dMMR/MSI-H Locally Advanced Rectal NCT07269249	National Cancer Institute, Naples	—
Recruiting	Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. NCT06940388	brenner baruch	Phase 2
Recruiting	Optimizing Immunotherapy Combined With Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer NCT07040098	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Phase 2
Recruiting	NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer NCT06459869	Akamis Bio	Phase 1
Recruiting	Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Ad NCT06761287	Centre Hospitalier Universitaire Saint Pierre	N/A
Active Not Recruiting	PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced R NCT06933251	Guangdong Provincial People's Hospital	Phase 2
Recruiting	SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced NCT06864013	First Affiliated Hospital of Zhejiang University	Phase 2
Recruiting	Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE Study NCT07020247	West China Hospital	Phase 3
Active Not Recruiting	A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy NCT06688786	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	N/A
Recruiting	Application of PET/MRI in the Evaluation of the Efficacy of Neoadjuvant Therapy for Locally Advanced Rectal Ca NCT06653452	Peking Union Medical College Hospital	N/A
Completed	AI-Based Prediction of Pathological Response in Rectal Cancer Patients Receiving Total Neoadjuvant Therapy NCT07049627	Ankara Etlik City Hospital	—
Completed	A Study to Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer NCT04009876	Fundación de investigación HM	Phase 2
Completed	Development and Validation of a Post-operative Risk Of Local Recurrence Model Integrating Serology and Evaluti NCT07351708	Cai Zerong	—