Trials / Conditions / Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH)

9 registered clinical trials studyying Langerhans Cell Histiocytosis (LCH) — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions NCT07371182	West China Second University Hospital	N/A
Recruiting	Modified LCH-III Regimen With or Without Luvometinib for Multisystem Pediatric Langerhans Cell Histiocytosis NCT07431060	West China Second University Hospital	N/A
Not Yet Recruiting	DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Y NCT07440290	Cancer Research UK	Phase 2 / Phase 3
Active Not Recruiting	Efficacy and Safety of XTD Regimen (Selinexor, Thalidomide and Dexamethasone) in Adult Patients With Relapsed/ NCT07204041	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Phase 2
Recruiting	Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell NCT07022834	West China Second University Hospital	Phase 2
Recruiting	Mirdametinib in Histiocytic Disorders NCT06153173	Children's Hospital Medical Center, Cincinnati	Phase 2
Suspended	Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease NCT05028621	Case Comprehensive Cancer Center	N/A
Active Not Recruiting	Lenalidomide for Adult Histiocyte Disorders NCT02523040	Dana-Farber Cancer Institute	Phase 2
Active Not Recruiting	CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation NCT01966367	Diane George	Phase 1 / Phase 2