| Recruiting | Scout Dose of Resin Microspheres NCT07476651 | Seoul National University Hospital | N/A |
| Not Yet Recruiting | FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cho NCT07353827 | Sun Yat-sen University | Phase 2 |
| Not Yet Recruiting | Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepa NCT07328919 | TransThera Sciences (Nanjing), Inc. | Phase 3 |
| Not Yet Recruiting | A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECIST NCT07208526 | Shanghai Zhongshan Hospital | N/A |
| Recruiting | Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, ICC or NEN NCT06735560 | Nantes University Hospital | N/A |
| Not Yet Recruiting | PErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinoma NCT07128290 | Federation Francophone de Cancerologie Digestive | Phase 2 |
| Not Yet Recruiting | Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III) NCT07161869 | Erasmus Medical Center | — |
| Completed | Interventional AI-Human Collaboration for Liver Tumor Diagnosis NCT07153783 | Shengjing Hospital | N/A |
| Recruiting | Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahe NCT07070700 | Fudan University | Phase 2 |
| Terminated | Streamlining Radioembolization for Intrahepatic Cholangiocarcinoma NCT07043348 | Seoul National University Hospital | — |
| Not Yet Recruiting | Second-line Regimen Combined With Radiotherapy Versus Without Radiotherapy in Patients With Locally Advanced/O NCT06946849 | Shanghai Zhongshan Hospital | Phase 2 |
| Recruiting | A Prospective Phase II Study of Postoperative Concurrent Chemoradiotherapy in Patients With Intrahepatic Chola NCT07063888 | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Phase 2 |
| Recruiting | Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant NCT06862934 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | — |
| Recruiting | Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally NCT06859684 | West China Hospital | Phase 2 |
| Recruiting | A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC NCT06925516 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Phase 2 |
| Active Not Recruiting | A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors NCT06777316 | Cogent Biosciences, Inc. | Phase 1 / Phase 2 |
| Terminated | Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA NCT06739252 | Peking University | Phase 2 |
| Recruiting | Additional Chemotherapy Administered Directly Into the Liver Using a Chemo Pump in Patients With Bile Duct Can NCT06888063 | Erasmus Medical Center | Phase 2 |
| Recruiting | Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectabl NCT06721286 | Tianjin Medical University Cancer Institute and Hospital | Phase 2 |
| Not Yet Recruiting | Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ± Lenvatinib As First-line Treatment for Advanced ICC NCT06648525 | Harbin Medical University | Phase 2 |
| Recruiting | Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers NCT07337850 | Tata Memorial Centre | — |
| Recruiting | Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanc NCT06852287 | Tianjin Medical University Cancer Institute and Hospital | Phase 2 |
| Recruiting | An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Charact NCT07101237 | Peking Union Medical College Hospital | — |
| Completed | An Exosomal miRNA-based Liquid Biopsy for ICC Detection NCT07225452 | City of Hope Medical Center | — |
| Completed | Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrah NCT07224737 | City of Hope Medical Center | — |
| Completed | HAIC Plus Systemic Chemotherapy, Lenvatinib and Toripalimab in Advanced ICC NCT07304388 | Sun Yat-sen University | Phase 2 |
| Recruiting | A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinom NCT05678270 | Beijing InnoCare Pharma Tech Co., Ltd. | Phase 2 |
| Recruiting | PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metast NCT05286814 | National Cancer Institute (NCI) | Phase 2 |
| Recruiting | A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening NCT07176962 | Yingbin Liu, MD, PhD, FACS | — |
| Completed | A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma NCT07479264 | First Affiliated Hospital, Sun Yat-Sen University | — |