HLH

11 registered clinical trials studyying HLH — 5 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HS NCT06839456	Children's Hospital of Philadelphia	Phase 1 / Phase 2
Recruiting	Gut Health in Children With Cancer NCT06899581	Great Ormond Street Hospital for Children NHS Foundation Trust	—
Completed	Efficacy and Safety of Interferon-Gamma Monoclonal Antibody Combined With Dexamethasone in the Treatment of Re NCT07531069	Fudan University	—
Unknown	Teniposide Incorporating Bu/Cy Conditioning Regimen for HLH With Central Nervous System Involvemen NCT06048107	Beijing Friendship Hospital	N/A
Recruiting	Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Sy NCT05306080	University of Pennsylvania	EARLY_Phase 1
Completed	Zanubrutinib for HLH NCT05320575	Beijing Friendship Hospital	Phase 3
Unknown	Thiotepa Incorporating TBI/Cy Conditioning Regimen for EBV-HLH With Central Nervous System Involvement NCT05854225	Beijing Friendship Hospital	N/A
Unknown	Low-dose CD20 Monoclonal Antibody Injection in Preemptive Treatment of PTLD in Patients With EBV-HLH/CAEBV NCT05258136	Beijing Friendship Hospital	N/A
Recruiting	Prospective Validation of the OHI Index NCT05882175	Meir Medical Center	—
Unknown	Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal NCT04758650	Universitair Ziekenhuis Brussel	Phase 2
Recruiting	Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders NCT04644016	Memorial Sloan Kettering Cancer Center	Phase 2