| Recruiting | Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities NCT05623111 | Rigshospitalet, Denmark | Phase 2 |
| Unknown | Noninvasive Cortical Neurostimulation For Diabetic Neuropathic Pain NCT06152887 | Jens Brøndum Frøkjær | N/A |
| Completed | Efficacy of Noninvasive Radiofrequency in Attenuating Diabetic Neuropathic Pain NCT05917249 | Cairo University | N/A |
| Recruiting | PDN Post Market, Multicenter, Prospective, Global Clinical Study NCT05301816 | Nevro Corp | N/A |
| Completed | Theta Burst Brain Stimulation in Diabetic Neuropathy Patients With Neuropathic Pain: Investigating Neural Mech NCT04988321 | Virginia Commonwealth University | N/A |
| Completed | The Effect of Foot and Ankle Exercise on Pain and Quality of Life in Patients With Diabetic Neuropathy NCT05670600 | Gazi University | N/A |
| Completed | Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy NCT04469270 | Helixmith Co., Ltd. | Phase 3 |
| Completed | The Effect of Foot Reflexology and Foot Bath on Paın And Qualıty of Lıfe Applıed to Dıabetıc Neuropathıc Paın NCT05920434 | Adiyaman Provincial Health Directorate | N/A |
| Completed | Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy NCT04055090 | Helixmith Co., Ltd. | Phase 3 |
| Completed | Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropath NCT03315598 | Seoul National University | N/A |
| Completed | Phase 3 Gene Therapy for Painful Diabetic Neuropathy NCT02427464 | Helixmith Co., Ltd. | Phase 3 |
| Completed | Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain. NCT03047278 | Natalia Valadares de Moraes | Phase 4 |
| Completed | A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Tr NCT02215252 | Pfizer | Phase 2 |
| Withdrawn | Safety and Efficacy Study of BC-DN-01 in Painful Diabetic Peripheral Neuropathy NCT01793350 | BioChemics, Inc. | Phase 1 / Phase 2 |
| Completed | Study to Evaluate MK-6096 in the Treatment of Painful Diabetic Neuropathy (PDN) in Adults (MK-6096-021) NCT01564459 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neu NCT01332149 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | A Study in Participants With Diabetic Peripheral Neuropathic Pain in China NCT01179672 | Eli Lilly and Company | Phase 3 |
| Unknown | Preliminary Assessment of the Efficacy of the VascuActive™ Device on Diabetic Peripheral Neuropathy NCT01214590 | VascuActive LTD | N/A |
| Completed | Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy. NCT05029297 | Arafarma Group, S.A. | Phase 3 |
| Completed | Study Of Pregabalin (Lyrica) In Patients With Painful Diabetic Peripheral Neuropathy NCT01057693 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | A Study in Painful Diabetic Neuropathy NCT01089556 | Eli Lilly and Company | Phase 3 |
| Terminated | A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to C NCT01063868 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Completed | A Study for Treatment of Pain in Patients With Diabetic Neuropathy. NCT00785577 | Eli Lilly and Company | Phase 2 |
| Completed | A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Pain Associated With Diabetic Peripheral N NCT00553280 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | Thermal Biofeedback for the Treatment of Diabetic Neuropathy NCT00858351 | Northwestern University | N/A |
| Completed | Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Pain Associated With Diabeti NCT00553475 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Completed | Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain NCT00507936 | AbbVie (prior sponsor, Abbott) | Phase 2 |
| Completed | Study for Safety and Effectiveness of RWJ-333369 (Carsibamate) for the Treatment of Diabetic Peripheral Neurop NCT00501202 | SK Life Science, Inc. | Phase 2 |
| Completed | Safety and Efficacy of AGN 203818 in Patients With Painful Diabetic Peripheral Neuropathy NCT00381719 | Allergan | Phase 2 |
| Completed | An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropa NCT00385671 | Eli Lilly and Company | Phase 4 |
| Terminated | Study Evaluating the Long-Term Safety of Desvenlafaxine Succinate Sustained-Release (DVS SR) in Subjects With NCT01050218 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Frequency Modulated Neural Stimulation (FREMS) in Symptomatic Diabetic Neuropathy NCT01628627 | Lorenz Biotech S.p.A. | Phase 4 |
| Completed | Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain NCT00266643 | Eli Lilly and Company | Phase 4 |
| Completed | A Study To Evaluate Pregabalin In Patients With Painful Diabetic Peripheral Neuropathy (DPN) NCT00156078 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Completed | Treatment of Painful Diabetic Neuropathy With Photon Stimulation NCT00539175 | East Bay Institute for Research and Education | N/A |
| Completed | Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy NCT00159679 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 4 |
| Terminated | Study Evaluating EAA-090 in Adult Outpatients With Neuropathic Pain Associated With Diabetic Neuropathy NCT00073034 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 2 |
| Completed | A Study for the Treatment of Painful Diabetic Neuropathy NCT00058968 | Eli Lilly and Company | Phase 3 |
| Completed | To Evaluate the Safety and Efficacy of Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy. NCT00150423 | Pfizer | Phase 3 |
| Completed | Safety and Efficacy of Pregabalin in Patients With Diabetic Peripheral Neuropathy. NCT00141401 | Pfizer | Phase 3 |