Clinical Trials Directory

Trials / Conditions / de Novo Myelodysplastic Syndromes

de Novo Myelodysplastic Syndromes

71 registered clinical trials studyying de Novo Myelodysplastic Syndromes.

StatusTrialSponsorPhase
CompletedOrgan-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hema
NCT02122081
Sumithira VasuPhase 1
CompletedCPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT02019069
Rondeep BrarPhase 2
WithdrawnSingle or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Maligna
NCT01652014
University of Medicine and Dentistry of New JerseyPhase 2
CompletedSirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukem
NCT01869114
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityPhase 2
CompletedDecitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treatin
NCT01707004
University of Wisconsin, MadisonPhase 2
CompletedIdarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodyspla
NCT01831232
Fred Hutchinson Cancer CenterN/A
CompletedDonor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01839916
University of ChicagoPhase 2
CompletedVaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing
NCT01588015
City of Hope Medical CenterPhase 1
WithdrawnMechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant
NCT01558778
Roswell Park Cancer InstituteN/A
CompletedTosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloi
NCT01567059
Fred Hutchinson Cancer CenterPhase 2
TerminatedRasburicase and Allopurinol in Treating Patients With Hematologic Malignancies
NCT01564277
Roswell Park Cancer InstitutePhase 2
CompletedCyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Trans
NCT01427881
Fred Hutchinson Cancer CenterPhase 2
CompletedSupersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or
NCT01305200
Children's Oncology GroupPhase 3
CompletedDeferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies
NCT01273766
Wake Forest University Health SciencesPhase 2
Active Not RecruitingInfection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic
NCT01199562
City of Hope Medical Center
CompletedBendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS
NCT01141725
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedPalifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Tran
NCT01233921
Martin, PaulN/A
CompletedInfusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematolo
NCT01175785
Nohla Therapeutics, Inc.Phase 2
CompletedClofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Adva
NCT01101880
University of WashingtonPhase 2
CompletedDifferentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome
NCT01165996
Case Comprehensive Cancer CenterPhase 1 / Phase 2
TerminatedDeferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload
NCT01159067
City of Hope Medical CenterPhase 2
TerminatedPlerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Bloo
NCT01076270
Fred Hutchinson Cancer CenterN/A
TerminatedRituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer
NCT01044745
University of NebraskaPhase 2
Completed5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodyspl
NCT01041443
City of Hope Medical CenterPhase 1
CompletedSunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy
NCT00890747
National Cancer Institute (NCI)Phase 1
CompletedIdentification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
NCT01146210
Children's Oncology Group
CompletedTreosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Pa
NCT00860574
Fred Hutchinson Cancer CenterPhase 2
CompletedFludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With
NCT00856388
Roswell Park Cancer InstituteN/A
CompletedOndansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant
NCT00795769
Fred Hutchinson Cancer CenterPhase 2
CompletedInternet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors
NCT00799461
Fred Hutchinson Cancer Research Center/University of Washington Cancer ConsortiumPhase 3
CompletedCediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-
NCT00475150
National Cancer Institute (NCI)Phase 2
CompletedDonor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other
NCT00450450
Children's Oncology GroupPhase 3
CompletedDonor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01093586
Case Comprehensive Cancer CenterPhase 2
TerminatedAflibercept in Treating Patients With Myelodysplastic Syndromes
NCT00509249
National Cancer Institute (NCI)Phase 2
CompletedBeclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem
NCT00489203
Fred Hutchinson Cancer CenterPhase 2
CompletedMS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myelo
NCT00462605
National Cancer Institute (NCI)Phase 2
CompletedGTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplast
NCT00459212
National Cancer Institute (NCI)Phase 1
CompletedCombination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysp
NCT00369317
Children's Oncology GroupPhase 3
CompletedSunitinib in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia
NCT00451048
National Cancer Institute (NCI)Phase 2
CompletedCyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis,
NCT00445744
Fred Hutchinson Cancer CenterN/A
CompletedLithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem
NCT00408681
Fred Hutchinson Cancer CenterN/A
CompletedVorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or M
NCT00357305
National Cancer Institute (NCI)Phase 1
CompletedBelinostat in Treating Patients With Myelodysplastic Syndromes
NCT00357162
National Cancer Institute (NCI)Phase 2
CompletedA Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Bloo
NCT00343798
Fred Hutchinson Cancer CenterPhase 1
CompletedEtanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Tr
NCT00309907
Children's Oncology GroupPhase 2
CompletedLow-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With
NCT00322101
Fred Hutchinson Cancer CenterPhase 3
TerminatedSJG-136 in Treating Patients With Relapsed or Refractory Acute Leukemia, Myelodysplastic Syndromes, Blastic Ph
NCT00301769
National Cancer Institute (NCI)Phase 1
CompletedAzacitidine and Etanercept in Treating Patients With Myelodysplastic Syndromes
NCT00118287
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedLenalidomide in Treating Young Patients With Relapsed or Refractory Solid Tumors or Myelodysplastic Syndromes
NCT00104962
National Cancer Institute (NCI)Phase 1
CompletedSB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic
NCT00098826
National Cancer Institute (NCI)Phase 1
CompletedTanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lym
NCT00098423
National Cancer Institute (NCI)Phase 1
CompletedXK469R in Treating Patients With Refractory Hematologic Cancer
NCT00095797
National Cancer Institute (NCI)Phase 1
CompletedIdarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or
NCT00096122
National Cancer Institute (NCI)Phase 1 / Phase 2
CompletedFludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Tran
NCT01056614
Fred Hutchinson Cancer CenterPhase 2
CompletedRebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic S
NCT00087204
National Cancer Institute (NCI)Phase 1
CompletedTacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone To
NCT00089011
Fred Hutchinson Cancer CenterPhase 2
CompletedCCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia,
NCT00084916
National Cancer Institute (NCI)Phase 2
CompletedMycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Mali
NCT00078858
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
TerminatedDecitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia
NCT00049582
National Cancer Institute (NCI)Phase 1
CompletedTipifarnib in Treating Patients With Myelodysplastic Syndromes
NCT00005845
National Cancer Institute (NCI)Phase 1
CompletedA Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete
NCT00045396
National Cancer Institute (NCI)Phase 2
CompletedHaploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer
NCT00049504
Fred Hutchinson Cancer CenterPhase 2
CompletedImatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction
NCT00025415
National Cancer Institute (NCI)Phase 1
CompletedThalidomide in Treating Patients With Myelodysplastic Syndrome
NCT00015990
National Cancer Institute (NCI)Phase 2
CompletedFludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Imm
NCT00014235
Fred Hutchinson Cancer CenterN/A
CompletedCombination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 i
NCT00006363
National Cancer Institute (NCI)Phase 3
CompletedFludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporin
NCT00006251
Fred Hutchinson Cancer CenterPhase 1 / Phase 2
CompletedFludarabine Phosphate, Low-Dose Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients Wi
NCT00005799
Fred Hutchinson Cancer CenterN/A
CompletedRadiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed
NCT00008177
Fred Hutchinson Cancer CenterPhase 1
CompletedCombination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogeno
NCT00002798
National Cancer Institute (NCI)Phase 3
CompletedHigh-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patient
NCT01177371
Case Comprehensive Cancer CenterPhase 2