| Recruiting | Antegrade Dissection and Re-entry Versus Retrograde Strategy in CTO PCI NCT06878729 | National Institute of Cardiology, Warsaw, Poland | N/A |
| Recruiting | Polish Registry of Percutaneous Coronary Intervention for Chronic Total Occlusions NCT07330622 | National Institute of Cardiology, Warsaw, Poland | — |
| Not Yet Recruiting | A MAajor RAdiation-based PCI Study in STEMI and NSTEMI NCT06565793 | Centre Cardiologique du Nord | — |
| Active Not Recruiting | AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS NCT06528821 | Powerful Medical | — |
| Unknown | Single-Arm Study Evaluating Use of the CORA Catheters for the Crossing of Coronary Chronic Total Occlusions NCT05848232 | ReFlow Medical, Inc. | Phase 3 |
| Recruiting | PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) NCT06542393 | Federal University of São Paulo | Phase 2 |
| Completed | STAR and Deferred Stenting Study NCT05089864 | Saint Luke's Health System | N/A |
| Active Not Recruiting | Comparison of the Diagnostic Performance and Costs of FFRB Vs. Standard Care in Suspected Coronary Artery Dise NCT06681584 | National Heart Centre Singapore | — |
| Active Not Recruiting | ANGiographic Evaluation of Left Main Coronary Artery INtErvention NCT04604197 | Fundación EPIC | N/A |
| Unknown | A Novel Non-Invasive Acoustic Diagnostic for the Diagnosis of Coronary Artery Disease The CAD-det Validation S NCT04562142 | AusculSciences Canada Inc. | N/A |
| Unknown | Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions NCT04744571 | Beijing Anzhen Hospital | N/A |
| Completed | Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First) NCT04691778 | National Institute of Cardiology, Warsaw, Poland | N/A |
| Completed | Patient Skin Dose in Interventional Radiology NCT04246125 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Observational Study Evaluating the Management of Chronic Coronary Occlusions In France NCT04281212 | French Cardiology Society | — |
| Completed | The Influence of Coronary Chronic Total Occlusion on Myocardial Perfusion on Computed Tomography NCT04465526 | National Institute of Cardiology, Warsaw, Poland | — |
| Unknown | Validation Of Quantitative Flow Ratio (QFR) - Derived Virtual Angioplasty NCT04200469 | Hospital Clínico Universitario de Valladolid | N/A |
| Terminated | Exercise in Patients With a Total Coronary Occlusion NCT03993522 | University of Hull | N/A |
| Recruiting | IRIS- DESyne X2 in the IRIS-DES Registry NCT03588481 | Seung-Jung Park | — |
| Unknown | Cohort B of the Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter NCT03719014 | Nitiloop Ltd. | N/A |
| Completed | Supplemental Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter NCT03717675 | Nitiloop Ltd. | N/A |
| Unknown | Functional Assessment-guided Angioplasty in Patients With Coronary Chronic Total Occlusion NCT03522038 | Shanghai Zhongshan Hospital | — |
| Terminated | Contrast Volume Reduction During PCI With the Use of a New Assisting Software Package NCT02927990 | Philips Clinical & Medical Affairs Global | — |
| Unknown | Comparative Study Between Intravascular Ultrasonography Guided and Angiography-guided Recanalization of Corona NCT03159650 | Assiut University | N/A |
| Unknown | Decision Aid in Chronic Total Occlusion (CTO) Patients NCT02963584 | The First Affiliated Hospital of Dalian Medical University | N/A |
| Terminated | Optical Coherence Tomography to Improve Outcome for Coronary Revascularisation Using Bioresorbable Vascular Sc NCT02683356 | Insel Gruppe AG, University Hospital Bern | N/A |
| Unknown | Coronary Revascularization Assessed by Stress PET NCT02931331 | Ochsner Health System | — |
| Completed | Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardia NCT02533128 | Miodrag Filipovic, Prof. Dr. med. | N/A |
| Unknown | Clinical Study Protocol - Debris Interventional Removal in ACS (DESIRE-ACS) NCT02325869 | Angioslide Ltd. | N/A |
| Completed | A Randomized Multicentre Trial to Evaluate the Utilization of Revascularization or Optimal Medical Therapy for NCT01760083 | Euro CTO Club | N/A |
| Completed | ABSORB FIRST is a Registry Designed to Evaluate the Safety and Performance of Absorb Bioresorbable Vascular Sc NCT01759290 | Abbott Medical Devices | — |
| Completed | XIENCE PRIME Japan Post-Marketing Surveillance (PMS) NCT01721096 | Abbott Medical Devices | — |
| Unknown | A Lead Rectangle to Lower the Operator's Radiation Exposure NCT01469195 | Sunnybrook Health Sciences Centre | — |
| Completed | XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval Randomized Control Trial (RCT) NCT01178268 | Abbott Medical Devices | Phase 4 |
| Terminated | Chronic Total Occlusion Registry NCT04041921 | Seung-Jung Park | — |
| Completed | Guidewire for Chronic Total Occlusion NCT00987610 | Tokai University | Phase 4 |
| Completed | AngelMed for Early Recognition and Treatment of STEMI NCT00781118 | Angel Medical Systems | Phase 3 |
| Completed | Non-acute Coronary occlusIon Treated By Everolimus ELuting Stent NCT00793221 | Raul Moreno | Phase 3 |
| Completed | Myeloid-Related Protein in Evaluation of Acute Chest Pain in the Emergency Departement NCT00657436 | University of Zurich | — |
| Completed | Safety and Efficacy of the CiTop™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries NCT00618020 | Ovalum | N/A |
| Completed | Advanced Cardiovascular Imaging Consortium NCT00640068 | Corewell Health East | — |
| Completed | Hemoglobin Based Oxygen Therapeutics in Elective Percutaneous Coronary Revascularization NCT00479895 | Biopure Corporation | Phase 2 |
| Completed | Safety and Efficacy of Autologous, Intracoronary Stem Cell Injections in Total Coronary Artery Occlusions NCT00365326 | Case Western Reserve University | Phase 1 |