| Not Yet Recruiting | Effects of AlignBabyCleft (ABaCleft) NCT05357092 | Universidad Complutense de Madrid | N/A |
| Not Yet Recruiting | Evaluation of a Novel Nasal Conformer in Pediatric Patients NCT06885801 | East Tennessee Children's Hospital | Phase 2 |
| Not Yet Recruiting | Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance NCT06411444 | Cairo University | N/A |
| Completed | Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients NCT07384338 | Al-Azhar University | N/A |
| Completed | Comparison Between Low Level Laser Therapy and Active Oxygen Releasing Gel on Wound Healing Cleft Lip Patients NCT06765837 | Faculty of Dental Medicine for Girls | Phase 1 |
| Completed | Botulinum Toxin Injection in Reducing Lip Scar Following Cleft Lip Repair NCT05559281 | Hams Hamed Abdelrahman | N/A |
| Completed | Unilateral Cleft Lip Repair : Modified Millard and Mishra Technique NCT05748340 | Cairo University | N/A |
| Completed | Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris NCT04277273 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Orbicularis Oris Z-plasty Modification of Modified Millard Technique and the Esthetic Outcome of Cleft Lip Rep NCT04627389 | Fayoum University | N/A |
| Withdrawn | Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities NCT04334590 | Johns Hopkins University | — |
| Withdrawn | Use of Titanium Plate in Rhinoplasty in Patients With Cleft Lip and Palate : Aesthetic and Functional Impact. NCT03572907 | Hospices Civils de Lyon | — |
| Active Not Recruiting | Targeting Surgeons' Decision-Making for Cleft Lip Surgery NCT03537976 | Tufts University | N/A |
| Completed | Characterization of Cleft Lip and Palate Conditions in Guatemala NCT04725370 | Children's Hospital of Philadelphia | — |
| Completed | Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair NCT03480607 | Mansoura University | Phase 4 |
| Enrolling By Invitation | Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) NCT02702869 | Duke University | — |
| Unknown | Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty NCT03839290 | Charles University, Czech Republic | — |
| Completed | Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair NCT02247193 | The University of Texas Health Science Center, Houston | Phase 1 / Phase 2 |
| Completed | Follow Ups of Parents With Infants With Cleft Lip and Palate NCT02415361 | Oslo University Hospital | N/A |
| Completed | Silicone Gel in the Treatment of Cleft Lip Scars NCT03314090 | Chang Gung Memorial Hospital | Phase 3 |
| Recruiting | Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate NCT01601171 | Centre Hospitalier Universitaire Vaudois | — |
| Unknown | Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment NCT02454998 | Chang Gung Memorial Hospital | N/A |
| Completed | FaceBase Biorepository NCT01252264 | Jeff Murray | — |
| Completed | Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip an NCT02329509 | Professor Fernando Figueira Integral Medicine Institute | N/A |
| Completed | Articulation and Phonology in Children With Unilateral Cleft Lip and Palate NCT00829101 | Region Skane | — |
| Completed | Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes NCT01380171 | Children's Healthcare of Atlanta | — |
| Completed | Oral Cleft Prevention Program NCT00397917 | University of Iowa | Phase 3 |
| Unknown | 3D Imaging of Hard and Soft Tissue in Orthognathic Surgery NCT00285714 | Radboud University Medical Center | N/A |
| Unknown | Osteogenesis and Dental Eruption Through Electrical Stimuli NCT00975208 | University of Guadalajara | — |
| Completed | Oral Cleft Prevention Trial in Brazil NCT00098319 | NICHD Global Network for Women's and Children's Health | Phase 3 |
| Completed | Systematic Pediatric Care for Oral Clefts - South America NCT00097149 | NICHD Global Network for Women's and Children's Health | N/A |
| Terminated | TWIST Human Gene and Cleft Lips and Palates NCT00213889 | University Hospital, Strasbourg, France | N/A |
| Completed | Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate NCT00070811 | University of North Carolina, Chapel Hill | — |
| Completed | Cleft Palate Surgery and Speech Development NCT00004639 | University of Florida | Phase 2 |
| Completed | Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment) NCT00340977 | National Institute of Environmental Health Sciences (NIEHS) | — |