| Recruiting | Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH) NCT07245264 | St. Olavs Hospital | Phase 2 / Phase 3 |
| Not Yet Recruiting | Prospective Multi-center Single Arm Study for Subjects With Chronic Subdural Hematoma Treated With i-ED COILs, NCT07214623 | Kaneka Medical America LLC | — |
| Recruiting | Neuroendoscopy-assisted Drainage Versus Burr Hole Drainage for Chronic Subdural Hematoma NCT07144423 | Beijing Tiantan Hospital | N/A |
| Recruiting | Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Sin NCT07324551 | Ohio State University | — |
| Recruiting | Aspirin Continuation or Discontinuation in Conservative Treatment for Chronic Subdural Hematoma NCT07240454 | Tao Liu | N/A |
| Not Yet Recruiting | Tranexamic Acid Therapy For The Treatment of Subdural Hematomas NCT06718751 | Baylor College of Medicine | Phase 2 |
| Recruiting | A National Study Examining the Most Effective Drainage Method After Burr Hole Evacuation of Chronic Subdural H NCT06621407 | Aalborg University Hospital | N/A |
| Recruiting | Restarting Early Versus Later Anticoagulation for Chronic Subdural Hematoma With Atrial Fibrillation NCT06696079 | Rahul Raj | N/A |
| Not Yet Recruiting | Puerto Rico Embolization of the Middle Meningeal Artery for the Treatment of Chronic Subdural Hematoma Trial ( NCT06466733 | Juan M. Ramos Acevedo | N/A |
| Withdrawn | Neurologic Deficits and Recovery in Chronic Subdural Hematoma NCT05900557 | University of New Mexico | N/A |
| Not Yet Recruiting | Efficacy and Safety of Chinese Herbal HuoXue LiShui Formula for Chronic Subdural Hematoma NCT06427980 | Beijing Tiantan Hospital | N/A |
| Recruiting | Middle Meningeal Artery Embolization for Patients With Chronic Subdural Hematoma NCT06772740 | Kazutaka Uchida | N/A |
| Recruiting | Implementation of an Enhanced Recovery Pathway for Burr-hole Drainage in Patients With a Chronic Subdural Hema NCT07421453 | Universitaire Ziekenhuizen KU Leuven | — |
| Withdrawn | The Efficacy of the Longeviti ClearFit Implant in Craniectomies for Post-Operative Monitoring in Chronic Subdu NCT06127615 | University of Kansas Medical Center | N/A |
| Recruiting | Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study NCT06347796 | The University of Texas Medical Branch, Galveston | N/A |
| Completed | Outcome of Chronic Subdural Hematoma Management With Double Burr Hole Craniotomy Versus Single Burr Hole Crani NCT07368101 | Services Institute of Medical Sciences, Pakistan | N/A |
| Recruiting | The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hemat NCT06401772 | Huashan Hospital | N/A |
| Recruiting | Spinal CSF Leaks in Chronic Subdural Hematoma NCT06323434 | University of Freiburg | — |
| Recruiting | Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection NCT06510582 | The Cooper Health System | Phase 1 / Phase 2 |
| Recruiting | Effect of the Postoperative Trendelenburg Position on Chronic Subdural Hematoma Recurrence NCT06911736 | Universidad de Antioquia | N/A |
| Recruiting | Nerve Block Anesthesia Combined With Sedative Anesthesia Versus General Anesthesia in Surgery for CSDH NCT05888389 | Beijing Tiantan Hospital | N/A |
| Withdrawn | Prospective Study on the Use of Middle Meningeal Artery Embolization for Chronic Subdural Haematoma NCT04500795 | Chinese University of Hong Kong | N/A |
| Unknown | YL-1 Needle Puncture vs BHC With Postoperative Exhaustive Drainage for CSDH NCT06072053 | Beijing Tiantan Hospital | — |
| Recruiting | Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH) NCT06181994 | Montefiore Medical Center | — |
| Recruiting | Efficacy of a Minimally Invasive Therapy Adjuvant to the Standards of Care by Cyanoacrylate Embolization NCT05374681 | University Hospital, Brest | N/A |
| Recruiting | Association Between Dietary Factors and Chronic Subdural Hematoma (DISH) NCT05599217 | Beijing Tiantan Hospital | — |
| Unknown | High Concentration Oxygen for Pneumocephalus After Evacuation of Chronic Subdural Haematoma NCT04725851 | Chinese University of Hong Kong | N/A |
| Withdrawn | Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD) NCT04966546 | University of New Mexico | EARLY_Phase 1 |
| Completed | Burr Hole Ultrasound Study NCT06134206 | Kepler University Hospital | N/A |
| Recruiting | Swedish Trial on Embolization of Middle Meningeal Artery Versus Surgical Evacuation in Chronic Subdural Hemato NCT05267184 | Region Skane | N/A |
| Unknown | Endovascular Embolization of Chronic Subdural Hematomas After Surgery NCT05220826 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Recruiting | Registry of Chronic Subdural Hematoma NCT06759428 | Erasmus Medical Center | — |
| Active Not Recruiting | Management of CSDH With or Without EMMA- a Randomized Control Trial NCT04750200 | University of Manitoba | N/A |
| Unknown | Tranexamic Acid in the Treatment of Residual Chronic Subdural Hematoma -2 NCT04898712 | Unity Health Toronto | Phase 2 |
| Completed | Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA NCT04816591 | Cerenovus, Part of DePuy Synthes Products, Inc. | N/A |
| Unknown | High Concentration Oxygen Therapy for Pneumocephalus in Chronic Subdural Haematoma: A Prospective Observationa NCT05143216 | Dr. David Yuen Chung CHAN | — |
| Completed | Defining Core Outcomes and Data Elements (CODE) in Chronic Subdural Haematoma NCT04850612 | University Hospital Plymouth NHS Trust | — |
| Unknown | Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hemat NCT04759196 | Université de Sherbrooke | Phase 4 |
| Unknown | Management of Anticoagulants and Antithrombotics in Patients With CSDH NCT05079295 | University Hospital of Ferrara | — |
| Terminated | A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System for Chronic Subdural Evacuat NCT04502745 | Mayo Clinic | N/A |
| Unknown | Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma Patients NCT04607447 | Huashan Hospital | N/A |
| Unknown | Middle Meningeal Artery Embolization With Liquid Embolic Agent for Treatment of Chronic Subdural Hematoma NCT04574843 | Mashhad University of Medical Sciences | N/A |
| Completed | Embolization of the Middle Meningeal Artery for the Prevention of Chronic Subdural Hematoma Recurrence in High NCT04372147 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Dartmouth Middle Meningeal Embolization Trial (DaMMET) NCT04270955 | Dartmouth-Hitchcock Medical Center | N/A |
| Unknown | Efficacy of Atorvastatin in Chronic Subdural Haematoma NCT03956368 | Chinese University of Hong Kong | Phase 3 |
| Unknown | Postoperative Balloninflation After Evacuation of cSDH NCT04060186 | Johann Wolfgang Goethe University Hospital | N/A |
| Completed | The Finnish Study of Intraoperative Irrigation Versus Drain Alone After Evacuation of Chronic Subdural Hematom NCT04203550 | Helsinki University Central Hospital | N/A |
| Withdrawn | Middle Meningeal Artery Embolization for Chronic Subdural Hematoma NCT04065113 | Washington University School of Medicine | — |
| Unknown | Middle Meningeal Artery (MMA) Embolization Compared to Traditional Surgical Strategies to Treat Chronic Subdur NCT04095819 | Atlantic Health System | N/A |
| Unknown | GET-UP Trial: Impact of an Early Out-of-bed Paradigm in Postoperative Outcomes of Chronic Subdural Hematomas NCT03788005 | Centro Hospitalar do Porto | N/A |
| Unknown | Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence NCT03831997 | Carilion Clinic | — |
| Unknown | General Anesthesia Versus Locoregional Anesthesia for Evacuation of Chronic Subdural Hematoma NCT03666949 | University Hospital, Caen | N/A |
| Completed | Chronic Subdural Hematoma and Aspirin NCT03120182 | University Hospital, Basel, Switzerland | N/A |
| Terminated | Tocilizumab (RoActemra) and Tranexamic Acid (Cyklokapron) Used as Adjuncts to Chronic Subdural Hematoma Surger NCT03353259 | Oslo University Hospital | Phase 2 / Phase 3 |
| Completed | Middle Meningeal Artery Embolization for Treatment of Chronic Subdural Hematoma NCT03307395 | Weill Medical College of Cornell University | N/A |
| Unknown | Bedside Versus Operating Room Burr-Hole Drainage of Chronic Subdural Hematoma (DECIDE) NCT03053895 | Hamilton Health Sciences Corporation | N/A |
| Unknown | Tranexamic Acid in the Treatment of Residual Chronic Subdural Hematoma NCT03280212 | Unity Health Toronto | Phase 3 |
| Unknown | Mgt of Chronic Subdural Hematoma Using Dexamethasone NCT02938468 | University of Calgary | Phase 2 / Phase 3 |
| Completed | The Swedish Study of Irrigation Fluid Temperature in the Evacuation of Chronic Subdural Hematoma NCT02757235 | Sahlgrenska University Hospital | N/A |
| Unknown | Tranexamic Acid in Chronic Subdural Hematomas NCT02568124 | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | Phase 2 / Phase 3 |
| Completed | Detecting Chronic Subdural Hematoma With Microwave Technology NCT02282228 | Sahlgrenska University Hospital | N/A |
| Unknown | The Clinical Study of Atorvastatin and Dexamethasone on Treatment for Chronic Subdural Hematoma in the Patient NCT02192320 | Oriental Neurosurgery Evidence-Based-Study Team | Phase 2 |
| Completed | Outcome of Single Burr Hole Under Local Anaesthesia in the Management of Chronic Subdural Hematoma NCT03447327 | Zagazig University | N/A |
| Terminated | Dexamethasone Versus Burr Hole Craniostomy for Symptomatic Chronic Subdural Hematoma NCT02111785 | University of Virginia | Phase 2 / Phase 3 |
| Completed | Effect and Safety Study of Atorvastatin to Treat Chronic Subdural Hematoma NCT02024373 | Oriental Neurosurgery Evidence-Based-Study Team | Phase 2 |
| Unknown | The Effect of Subdural Drain Placement After Burr Hole Evacuation of Chronic Subdural Haematomas on Recurrence NCT01785797 | Kwong Wah Hospital | Phase 3 |
| Completed | A Prospective Randomized Study Evaluating the Recurrence Rate of Chronic Subdural Hematoma After Placing a Sub NCT01869855 | Kantonsspital Aarau | N/A |
| Completed | To Scan or Not to Scan: The Role of Follow-up CT Scanning for Management of Chronic Subdural Hematoma After Ne NCT01624545 | Insel Gruppe AG, University Hospital Bern | N/A |
| Unknown | Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hem NCT01470040 | Hadassah Medical Organization | Phase 4 |
| Completed | Randomized Controlled Trial Investigating Optimal Treatment for Chronic Subdural Hematoma NCT02655445 | Universitair Ziekenhuis Brussel | N/A |