| Recruiting | Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI) NCT07357428 | Paradromics | N/A |
| Recruiting | Feasibility and Safety of a Combined Augmented Reality and Functional Electrical Stimulation System NCT07299734 | University Health Network, Toronto | EARLY_Phase 1 |
| Recruiting | VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communicatio NCT07224256 | Neuralink Corp | N/A |
| Recruiting | GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Contr NCT07127172 | Neuralink Corp | N/A |
| Recruiting | Spinal Stimulation for Upper Extremity Recovery in the Home NCT06743607 | Craig Hospital | N/A |
| Recruiting | UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of NCT06992596 | Neuralink Corp | N/A |
| Completed | ExaStim Upper Limb Home Use Clinical Validation Study NCT06850363 | Niche Biomedical, Inc. dba ANEUVO | N/A |
| Recruiting | Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury NCT06541041 | Stanford University | — |
| Recruiting | Robot-assisted Vs. Conventional Occupational Therapy of the Upper Limb in Individuals with Cervical Spinal Cor NCT06775925 | Swiss Paraplegic Research, Nottwil | N/A |
| Recruiting | Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery NCT06701422 | Columbia University | N/A |
| Recruiting | CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices NCT06700304 | Neuralink Corp | N/A |
| Unknown | EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis NCT06169696 | Synaptrix Labs Inc. | N/A |
| Recruiting | Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spina NCT06225245 | The Methodist Hospital Research Institute | N/A |
| Recruiting | Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01) NCT06511934 | Leigh R. Hochberg, MD, PhD. | N/A |
| Active Not Recruiting | Rebuilding Inter-limb Transfer in Cervical SCI NCT06440538 | The Cleveland Clinic | EARLY_Phase 1 |
| Recruiting | Nerve Transfer to Improve Function in High Level Tetraplegia NCT06288763 | Washington University School of Medicine | — |
| Recruiting | Precise Robotically IMplanted Brain-Computer InterfacE NCT06429735 | Neuralink Corp | N/A |
| Active Not Recruiting | Incomplete Cervical SCI Without Instability NCT05653206 | AO Foundation, AO Spine | — |
| Recruiting | A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Sur NCT06087445 | Ohio State University | N/A |
| Terminated | Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal C NCT06101199 | Thomas Jefferson University | N/A |
| Completed | Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Fun NCT05601661 | The University of Texas Health Science Center, Houston | N/A |
| Unknown | Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehab NCT05665998 | Ecole Polytechnique Fédérale de Lausanne | N/A |
| Recruiting | Study of Individualized, Precise and Standardized Cervical Open-door Surgery for Cervical Spinal Stenosis NCT05786313 | Xijing Hospital | N/A |
| Recruiting | Neurostimulation for Respiratory Function After Spinal Cord Injury NCT05756894 | Shirley Ryan AbilityLab | N/A |
| Recruiting | Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord In NCT05343130 | Instituto Nacional de Rehabilitacion | N/A |
| Completed | Blood Flow Restriction Resistance Exercise in Lower Cervical Spinal Cord Injury Patients NCT05425238 | Riphah International University | N/A |
| Unknown | Laminectomy Alone Versus Laminectomy and Fusion for Traumatic Cervical Spinal Cord Injury Without Instability NCT05360524 | Assiut University | N/A |
| Active Not Recruiting | COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis NCT05035823 | Synchron Medical, Inc. | N/A |
| Completed | Short-Term Outcomes Of Subaxial Cervical Injuries NCT05678803 | Assiut University | — |
| Enrolling By Invitation | Improving Upper Extremity Function and Trunk Stability After Cervical Spinal Cord Injury (SCI) NCT05191121 | Craig Hospital | N/A |
| Completed | Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI NCT04995796 | Washington University School of Medicine | N/A |
| Unknown | Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity NCT04815967 | Supernus Pharmaceuticals, Inc. | Phase 2 / Phase 3 |
| Unknown | Motor Recovery Training for Hand and Digits in Stroke and SCI NCT04688229 | Shirley Ryan AbilityLab | N/A |
| Recruiting | Spinal Cord Associative Plasticity Study NCT05163639 | Columbia University | EARLY_Phase 1 |
| Unknown | Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury NCT05638191 | University of British Columbia | — |
| Completed | Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function NCT04777149 | Shepherd Center, Atlanta GA | N/A |
| Unknown | A Comparative Study of High and Low Tidal Volume in Preventing Hypoxemia in Patients With Mechanical Ventilati NCT04949971 | Peking University Third Hospital | — |
| Recruiting | Dysphagia After Anterior Cervical Spine Surgery NCT04855838 | Umeå University | N/A |
| Completed | Diaphragm Pacing in Individuals With Spinal Cord Injuries NCT04179799 | University of Florida | — |
| Active Not Recruiting | Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury NCT04041063 | Burke Medical Research Institute | Phase 2 |
| Completed | Restorative Neuromodulation for Upper Extremity Functions NCT04183998 | The Hong Kong Polytechnic University | N/A |
| Unknown | C-MAC Videolaryngoscope Intubation and Cervical Spine Motion NCT03567902 | Seoul National University Hospital | N/A |
| Unknown | Treatment of Cervical Spinal Cord Injury With Imatinib - a Safety and Feasibility Study NCT02363361 | Professor Mikael Svensson, MD PhD | Phase 2 |
| Terminated | Restoring Hand Function Utilizing Nerve Transfers in Persons With Cervical Spinal Cord Injuries NCT03451474 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Supporting Patient Decisions About UE Surgery in Cervical SCI NCT03464409 | Washington University School of Medicine | N/A |
| Terminated | Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury NCT02669849 | Vertex Pharmaceuticals Incorporated | Phase 2 / Phase 3 |
| Completed | Dose Escalation Study of AST-OPC1 in Spinal Cord Injury NCT02302157 | Lineage Cell Therapeutics, Inc. | Phase 1 / Phase 2 |
| Terminated | Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury NCT02163876 | StemCells, Inc. | Phase 2 |
| Withdrawn | Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries NCT01712698 | Washington University School of Medicine | — |
| Completed | Linking Brain to Behaviour Research in SCI NCT01963026 | Adelante, Centre of Expertise in Rehabilitation and Audiology | N/A |
| Active Not Recruiting | Spinal Cord Neuromodulation for Spinal Cord Injury NCT02313194 | University of California, Los Angeles | Phase 1 / Phase 2 |
| Unknown | Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation NCT01800409 | NHS Greater Glasgow and Clyde | N/A |
| Unknown | Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity NCT01579604 | University of British Columbia | Phase 4 |
| Completed | Comparing Outcomes of Elbow Extension Tendon Transfers NCT01204736 | VA Office of Research and Development | — |