| Not Yet Recruiting | A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic Stroke NCT07386262 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema NCT06515145 | Institute of Liver and Biliary Sciences, India | N/A |
| Recruiting | Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct T NCT07118345 | Xuanwu Hospital, Beijing | N/A |
| Unknown | Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Br NCT06096415 | Abalonex, LLC | Phase 2 |
| Completed | AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation NCT06018545 | Oxford University Hospitals NHS Trust | — |
| Unknown | Clinical Significance of DKK2 Protein in Cerebral Ischemia-reperfusion Injury NCT05585255 | Nanfang Hospital, Southern Medical University | — |
| Unknown | Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH NCT06009016 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Completed | Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients NCT05796349 | Jieshi Ma | — |
| Completed | The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers NCT05200728 | Jiangsu Simcere Pharmaceutical Co., Ltd. | Phase 1 |
| Completed | Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study NCT07422636 | University of Florence | — |
| Withdrawn | Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension NCT03409237 | Neuromed IRCCS | — |
| Completed | Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage NCT04088630 | Wake Forest University Health Sciences | EARLY_Phase 1 |
| Terminated | Trial of Dexamethasone for Traumatic Brain Injured Patients With Brain Contusions and Pericontusional Edema NCT04303065 | Jon Pérez Bárcena | Phase 3 |
| Unknown | Study on the Relationship Between Asymmetric Vascular Sign of Cortex and Prognosis in Massive Cerebral Infarct NCT04247659 | The Second Hospital of Hebei Medical University | Phase 4 |
| Completed | Conventional Hemodialysis Versus Post-Dilution Hemofiltration in Incident RRT NCT05060159 | Instituto Nacional de Cardiologia Ignacio Chavez | N/A |
| Completed | Antisecretory Factor in Primary Glioblastoma 1 NCT04116138 | Peter Siesjö | Phase 1 / Phase 2 |
| Completed | Noninvasive Monitoring of Cerebral Blood Flow Autoregulation NCT05170295 | Ochsner Health System | — |
| Unknown | Molecular Mechanisms of Malignant Cerebral Edema After LHI NCT03703284 | Xuanwu Hospital, Beijing | — |
| Withdrawn | Small-Volume, Patient-Specific, Balanced Hypertonic Fluid Protocol Validation NCT03330704 | Stanford University | EARLY_Phase 1 |
| Active Not Recruiting | Implementation of Neuro Lung Protective Ventilation NCT03243539 | Colin Grissom | N/A |
| Terminated | Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metast NCT02460874 | University of Alabama at Birmingham | Phase 1 / Phase 2 |
| Completed | Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access NCT03276494 | Ohio State University | Phase 2 |
| Completed | Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study NCT03000283 | Jesse Corry | Phase 1 |
| Completed | Evaluation of the Cerebral Edema in Children Having Diabetic Ketoacidosis NCT02937441 | Cukurova University | — |
| Unknown | Acute Ischaemic STROKE: From LAboratory to the Patient's BED NCT05725694 | Istituto di Neuroscienze Consiglio Nazionale delle Ricerche | — |
| Withdrawn | Study of Stroke Related Edema Treatments NCT01954290 | University of Florida | Phase 2 |
| Completed | Histamine Glutamate Antagonism in Stroke NCT02142712 | University of Florida | Phase 2 |
| Withdrawn | Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain Injury NCT01605357 | Massachusetts General Hospital | Phase 1 / Phase 2 |
| Completed | Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis NCT01365793 | University of California, Davis | Phase 3 |
| Completed | Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention NCT01060969 | Sheba Medical Center | N/A |
| Terminated | Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme NCT00243022 | Ali Altunkaya | Phase 2 |