| Not Yet Recruiting | Long-term Outcome Evaluation of Patients Undergoing Autologous Chondrocyte Transplantation Delivered on Biomat NCT06238947 | Istituto Ortopedico Rizzoli | — |
| Not Yet Recruiting | Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications NCT07240649 | Jay C. Buckey Jr. | Phase 4 |
| Not Yet Recruiting | Tissue Engineered Cartilage to Repairing Articular Cartilage Defects NCT07094100 | The First Affiliated Hospital of Xinxiang Medical College | N/A |
| Recruiting | The Hyalex First-in-Human Study NCT06344481 | Hyalex Orthopaedics, Inc. | N/A |
| Not Yet Recruiting | CAsting and REhabilitation Versus Supervised Neglect for Osteochondral Lesions of the Talus in the Pediatric P NCT06220539 | Tristan Buck | N/A |
| Recruiting | Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis NCT06082531 | Xijing Hospital | N/A |
| Completed | Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions NCT06078072 | University Medical Centre Ljubljana | — |
| Unknown | Synovial Tissue and Fat Pad Stromal Vascular Fraction Bioengineering in Patients With Knee Articular Cartilage NCT05120700 | University of Sao Paulo General Hospital | Phase 1 / Phase 2 |
| Terminated | PROPER Trial of Pain and Inflammation After Knee Arthroscopy NCT05149287 | Austin V Stone | Phase 2 |
| Unknown | Treatment of Cartilage Defects With Peripheral Blood Stem Cells NCT04953572 | Peking University Third Hospital | Phase 1 |
| Unknown | Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defec NCT05328674 | eMKa MED Medical Center | N/A |
| Unknown | The Impact of Covid-19 on Patients Waiting for Knee Surgery NCT05124613 | University of Manchester | — |
| Terminated | Assessment Micro-anatomy of the Menisci and Cartilage After Isolated Acute ACL Injury With MRI at 7T NCT05433012 | Balgrist University Hospital | N/A |
| Terminated | Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee NCT04537013 | Geistlich Pharma AG | N/A |
| Terminated | ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry NCT04301258 | AlloSource | — |
| Completed | 7T MRI to Evaluate Cartilage Defects in the Knee NCT04118023 | The Methodist Hospital Research Institute | — |
| Recruiting | The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction NCT04184687 | Istituto Ortopedico Rizzoli | N/A |
| Active Not Recruiting | Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Pate NCT03873545 | AlloSource | — |
| Active Not Recruiting | Impact of Mesenchymal Stem Cells in Knee Osteoarthritis NCT03477942 | University Hospitals Cleveland Medical Center | Phase 1 |
| Unknown | Clinical Study of Decalcification Bone Scaffold for Cartilage Lesions of the Knee NCT03321812 | Peking University Third Hospital | N/A |
| Completed | Spontaneous Healing of ARticular Cartilage (SHARC) NCT04889443 | Keele University | — |
| Unknown | Effect of Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis NCT03962270 | Peking University Third Hospital | N/A |
| Completed | Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation NCT04739930 | Rush University Medical Center | N/A |
| Unknown | Muscle Function and Traumatic Knee Injury in Sports NCT03479775 | Lund University | — |
| Completed | Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair NCT02696876 | University of Leeds | N/A |
| Terminated | Second Line Treatment of Knee Osteochondral Lesion With Treated Osteochondral Graft NCT02430558 | TBF Genie Tissulaire | Phase 1 / Phase 2 |
| Completed | Autologous Cartilage Implantation vs Arthroscopic Debridement NCT02636881 | University Hospital, Akershus | N/A |
| Completed | Norwegian Cartilage Project - Microfracture NCT02637505 | University Hospital, Akershus | N/A |
| Completed | Effectiveness of Autologous Platelet-rich Plasma on Knee Cartilage Injury NCT03024801 | Chinese PLA General Hospital | N/A |
| Completed | BioPoly RS Knee Registry Study for Cartilage Defect Replacement NCT01473199 | BioPoly LLC | N/A |
| Active Not Recruiting | ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee NCT01458782 | University Hospital of North Norway | N/A |
| Completed | Study to Compare Efficacy and Safety of Cartistem and Microfracture in Patients With Knee Articular Cartilage NCT01041001 | Medipost Co Ltd. | Phase 3 |
| Completed | Prospective Registry of Anterior Cruciate Ligament Reconstructions NCT04135950 | State University of New York at Buffalo | — |
| Completed | A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage D NCT02993510 | Geistlich Pharma AG | Phase 3 |
| Unknown | Hyaluronic Acid Injection Post Arthroscopy - Does it Improve Immediate Function? Double Blind Controlled Prosp NCT01442571 | Hadassah Medical Organization | Phase 1 / Phase 2 |