| Withdrawn | Knee Prosthetic Joint Infection Antibiotic Elution NCT06023238 | University of Pittsburgh | — |
| Recruiting | Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement NCT05736666 | University of Illinois at Chicago | N/A |
| Enrolling By Invitation | Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care NCT06469177 | Nova Scotia Health Authority | N/A |
| Recruiting | Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surge NCT06563531 | Clinique Pasteur Lanroze | N/A |
| Active Not Recruiting | Comprehensive SRS Regenerex Tissue Attachment NCT06615739 | Zimmer Biomet | — |
| Active Not Recruiting | Long-term Outcomes of Complex Conversion Total Hip Arthroplasty NCT06533020 | University of North Carolina, Chapel Hill | — |
| Recruiting | Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions ( NCT06527664 | Istituto Ortopedico Rizzoli | — |
| Recruiting | Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection NCT06293352 | Northwestern University | N/A |
| Recruiting | Effect of Game Activity and Stress Ball on Anxiety and Vital Signs NCT06523413 | Suleyman Demirel University | N/A |
| Recruiting | Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome? NCT06308965 | Ziekenhuis Oost-Limburg | N/A |
| Completed | The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA NCT06112548 | Damascus University | N/A |
| Unknown | BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients NCT06103552 | Ottawa Hospital Research Institute | N/A |
| Recruiting | Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability? NCT06025448 | Lovisenberg Diakonale Hospital | N/A |
| Completed | Pre vs Post Block in Total Knee Arthroplasty (TKA) NCT05974501 | University of Miami | Phase 4 |
| Recruiting | Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty NCT05845021 | Johns Hopkins University | N/A |
| Recruiting | l Investigation of Robotic-assisted TKA (RA-TKA) With Skywalker and Evolution Medial Pivot Knee (eMP Knee) NCT06969222 | Orthopaedic Department of General University Hospital of Laria | N/A |
| Unknown | LocalVancomycinPowderToPreventPeriprostheticJointInfection. NCT05697965 | Assiut University | Phase 2 |
| Completed | Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia NCT05707234 | University of Liege | Phase 4 |
| Unknown | Analysis of Defined Elements on DXA in Patients Undergoing Hip Arthroplasty NCT06324708 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | N/A |
| Recruiting | Ototoxicity in Patients With MoM Hip Bearings NCT06885411 | Reinier Haga Orthopedisch Centrum | — |
| Unknown | Physiotherapy for Arthrofibrosis Following Knee Replacement. NCT05459259 | University of Nottingham | — |
| Unknown | Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA NCT05509946 | Indonesia University | Phase 2 / Phase 3 |
| Completed | Assessment of Postural Stability in Patients With Total Knee Arthroplasty NCT05420194 | Acibadem University | — |
| Recruiting | Achilles Tendon for the Treatment of Gluteus Medius Insufficiency NCT05206838 | Sahlgrenska University Hospital | N/A |
| Recruiting | The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty NCT05216666 | Sahlgrenska University Hospital | N/A |
| Terminated | Anaverse™ Glenoid System and Its Instrumentation NCT05215600 | Zimmer Biomet | — |
| Unknown | Validity and Reliability of High-Activity Arthroplasty Score NCT05211310 | Afyonkarahisar Health Sciences University | — |
| Completed | Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration i NCT05325671 | Department of Medical Services Ministry of Public Health of Thailand | N/A |
| Completed | Evaluation of Noise Induced by Ceramic-ceramic Friction Torques of Total Hip Prostheses With Customized Femora NCT05014932 | GCS Ramsay Santé pour l'Enseignement et la Recherche | — |
| Completed | Validation and Feasibility in Clinical Practice and Concordance of an Automated System Coupling an RGB-D Camer NCT05292157 | Centre Hospitalier Universitaire de Nice | — |
| Completed | Effects of Music and Comedy Application on Pain and Kinesyophobia in Patients With TKA NCT05471778 | Malatya Turgut Ozal University | N/A |
| Withdrawn | Liposomal Bupivacaine in Adductor Canal Blocks (ACB) NCT04539730 | University of Miami | Phase 4 |
| Completed | Kinesiotape for Edema After Bilateral Total Knee Arthroplasty NCT05013879 | Montefiore Medical Center | N/A |
| Unknown | Infrapatellar Fat Pad Excision in Total Knee Arthroplasty NCT05060536 | NHS Greater Glasgow and Clyde | N/A |
| Recruiting | Functional Outcome After ORIF or Arthroplasty for Femoral Neck Fracture NCT06152198 | Uppsala University | N/A |
| Recruiting | Persona Revision Knee System Outcomes NCT04821154 | Zimmer Biomet | — |
| Recruiting | Urinary Retention After Arthroplasty NCT04707001 | Central Finland Hospital District | N/A |
| Active Not Recruiting | Plasmafit® Revision Structan® Hip Endoprosthesis Cup NCT04255966 | Aesculap AG | — |
| Unknown | Correlation of Intramedullary Pressure and Systemic Inflammatory Parameters in Cemented Femoral Stem NCT04913623 | University Clinical Centre of Kosova | — |
| Completed | Anterior Knee Pain in Mobile Bearing Versus Fixed Bearing in TKA NCT05696418 | Damascus University | N/A |
| Completed | Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA NCT05691751 | Damascus University | N/A |
| Completed | Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty NCT04691362 | University of Liege | Phase 4 |
| Completed | Efficacy of iPACK After Unilateral TKA NCT04565093 | King Khalid University Hospital | N/A |
| Completed | Modelling and AI Using Sensor Data to Personalise REHABilitation Following Joint Replacement NCT04289025 | Norfolk and Norwich University Hospitals NHS Foundation Trust | N/A |
| Completed | Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty NCT04437888 | Dartmouth-Hitchcock Medical Center | EARLY_Phase 1 |
| Unknown | Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings NCT04520841 | University of Lausanne Hospitals | N/A |
| Unknown | Sleep and Cognition After Ambulatory Hip and Knee Arthroplasty NCT04227873 | Hvidovre University Hospital | — |
| Completed | Arthroplasty Versus Internal Fixation for Undisplaced Femoral Neck Fracture NCT04075461 | University of Southern Denmark | N/A |
| Unknown | DELTA Multihole TT Study NCT04375345 | University Hospital Bratislava | — |
| Completed | Is Self-transfusion Safe After Total Knee Arthroplasty in Terms of Nephrotoxicity of Gentamicin From Bone Ceme NCT04505748 | University Hospital, Alexandroupolis | N/A |
| Terminated | ASHCOM Shoulder System and Its Related Instruments NCT04258605 | Zimmer Biomet | — |
| Completed | Bypass PACU in Knee and Hip Arthroplasty NCT03984942 | Niklas Ingemann Nielsen | — |
| Unknown | Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA NCT05181566 | Korea University Guro Hospital | N/A |
| Completed | Lumbar Erector Spinae Plane Block: Cadaveric Study NCT04166188 | University of Sao Paulo General Hospital | N/A |
| Completed | Large Doses of Methylprednisolone Combined With Gabapentin in Total Knee Arthroplasty NCT04653415 | Jagiellonian University | Phase 4 |
| Completed | Multi-variable Prediction Model of Total Knee Replacement Outcome NCT03894514 | University of Valencia | — |
| Unknown | ARTHR-IS (Arthroplasties' Infections Due to Staphylococcus Aureus) NCT03826108 | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | — |
| Unknown | REVISITS: Revision Single or Two Stage Surgery NCT03741296 | Unity Health Toronto | N/A |
| Completed | Change of Intramedullar Pressure After Implantation of Hip Prothesis NCT03930537 | University Clinical Centre of Kosova | N/A |
| Unknown | Calprotectin in Chronic Prosthetic Joint Infection NCT05060952 | Technical University of Munich | — |
| Active Not Recruiting | Failure Analysis of Patellofemoral Arthroplasty NCT04772625 | Anders Odgaard | — |
| Completed | The Effect of Releasing the Tourniquet in Total Knee Replacement Before Closure on the Blood Loss , Joint Effu NCT04810000 | Yazan Saleh Rajab Hammad | — |
| Unknown | Pharmacogenetics for Pain Management in Joint Replacement Patients NCT03772535 | Anderson Orthopaedic Research Institute | Phase 3 |
| Completed | Incidence of 30 Day Return to Hospital Following Same Day Discharge Total Hip Arthroplasty NCT04120324 | University of British Columbia | — |
| Completed | The Analysis of Posterior Soft Tissue Repair Durability NCT04490304 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | N/A |
| Completed | Sleep Behavior and Rest-activity Circadian Rhythm (RAR) in Hip/Knee Prosthesis NCT03572920 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Unknown | Outcome of Total Hip Replacement in Patients With Chronic Renal Disease NCT03522285 | Assiut University | — |
| Completed | DAIR for Infected Total Hip Arthroplasty - Does the Operative Approach Influence the Functional Result? NCT03161990 | University Hospital, Akershus | — |
| Completed | The Whole Body Vibration Training for Total Knee arthroplasty-the Improvement of the Lower Limb NCT04107350 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Completed | Varus Stem Positioning of a Cementless Anatomical THA. (VARABG) NCT04653090 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Acupuncture for Post Operative Pain Following Total Knee or Hip Arthroplasty NCT03415204 | Ziv Hospital | N/A |
| Unknown | Recognition and Treatment of Dysglycemia. AGS - Acute Glucose Service NCT03306810 | Joint Authority for Päijät-Häme Social and Health Care | N/A |
| Completed | Multimodal Sleep Pathway for Shoulder Arthroplasty NCT03269760 | University of California, San Francisco | Phase 1 |
| Completed | Total Knee Arthroplasty With the Medial-Pivot Knee System NCT03677518 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Radial Head Arthroplasty A Clinical and Radiological Comparison of Monopolar and Bipolar Radial Head Arthropla NCT03379935 | Sundsvall Hospital | — |
| Unknown | Infection Rate of One-Stage Bilateral TKR - One Surgeon Sequential vs. Two Surgeon Simultaneous: A Randomized NCT04413565 | Bezmialem Vakif University | N/A |
| Completed | Selective Thromboembolism Prophylaxis After Arthroplasty NCT03804697 | Guangdong Provincial People's Hospital | N/A |
| Completed | Impact on Muscle Strength, Quality of Life and Functionality in Individuals Submitted to Hip Arthroplasty: a P NCT03079479 | Faculdade de Ciências Médicas da Santa Casa de São Paulo | — |
| Completed | Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty NCT03289247 | Hvidovre University Hospital | N/A |
| Completed | Early Clinical and Radiological Outcomes of Uncemented Fully Coated Stem With Patients of 85 Years and More, C NCT05969366 | Central Hospital, Nancy, France | — |
| Completed | Joint Awareness After Total Knee Replacement NCT06033625 | Saglik Bilimleri Universitesi | — |
| Completed | Safety of Total Knee Replacement Surgery Before and After the Implementation of Enhanced Recovery Program NCT05028426 | Groupe Hospitalier de la Rochelle Ré Aunis | — |
| Completed | Investigation of the Effects of Balance Training on Balance and Functional Status Patients With Total Hip Arth NCT04433962 | Ege University | N/A |
| Completed | General vs Spinal Anesthesia for Total Joint Arthroplasty-Anterior Approach: A Single-Institution Observationa NCT06320691 | Bezmialem Vakif University | — |
| Completed | A Randomized RSA Study Comparing HXLPE to Conventional Polyethylene in Cemented Total Hip Arthroplasty NCT04322799 | Umeå University | N/A |
| Completed | Undisplaced Femoral Neck Fractures NCT03392285 | Sundsvall Hospital | — |
| Completed | Total Hip Arthoplastry Revision by Dual-mobility Acetabular Cup Cemented in a Metal Reinforcement NCT03680443 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Length of Stay and Complications in High-risk Patients Receiving Fast-track Total Hip (THA) or Knee- Alloplast NCT01515670 | Rigshospitalet, Denmark | — |
| Completed | An Assessment of 4 Different Bearing Types in Hip Replacement Types to Analsye the Lowest Wear Rates of Polyet NCT03900039 | Unity Health Toronto | N/A |
| Unknown | Evaluation of Metal-on-conventional-polyethylene vs Ceramic-on-ceramic Articulating Surfaces in Total Hip Arth NCT03692364 | Sahlgrenska University Hospital | N/A |
| Completed | Effects of Navigation Versus Conventional Total Knee Arthroplasty on the Levels of Inflammation Markers NCT03163888 | Chang Gung Memorial Hospital | — |
| Completed | Osteolysis Development Around Uncemented Cups With or Without Screw Holes NCT03692351 | Sahlgrenska University Hospital | N/A |