| Active Not Recruiting | Voluntary Isocapnic Hyperpnea in Hypoxia to Mitigate Acute Mountain Sickness NCT07126834 | Institute of Sport - National Research Institute, Poland | N/A |
| Completed | Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness NCT06450899 | University of Colorado, Denver | Phase 2 |
| Not Yet Recruiting | EleVation carE: a Randomized Controlled Trial on the Prevention of Acute Mountain Sickness With Suxiao Jiuxin NCT06531161 | Peking University First Hospital | Phase 2 / Phase 3 |
| Recruiting | HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle NCT06499714 | University of Zurich | — |
| Completed | HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to Men NCT06499727 | University of Zurich | Phase 4 |
| Completed | CO2 Supplement for Treatment of Acute Mountain Sickness NCT06393998 | State Key Laboratory of Respiratory Disease | N/A |
| Unknown | The Effect of Continuous Positive Pressure Ventilation on Symptoms of Acute Mountain Sickness NCT06145113 | University of Colorado, Denver | N/A |
| Completed | Risk Factors Associated With High Altitude Sickness: A Case-Control Study NCT06039475 | B.P. Koirala Institute of Health Sciences | — |
| Unknown | The Effects of Intermittent Hypoxia on Acute Hypoxic Injury NCT05733338 | Capital Medical University | N/A |
| Completed | Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude NCT05798416 | State Key Laboratory of Respiratory Disease | N/A |
| Completed | Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide NCT05023941 | Ji Xunming,MD,PhD | Phase 4 |
| Completed | Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness NCT06310642 | CHRISTUS Health | Phase 4 |
| Completed | Colorado-Oregon Altitude Study NCT05734716 | University of Oregon | Phase 4 |
| Completed | Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude NCT04111263 | United States Army Research Institute of Environmental Medicine | N/A |
| Completed | Sickness Evaluation at Altitude With Acetazolamide at Relative Doses NCT03828474 | Stanford University | Phase 1 |
| Completed | Sickness Evaluation at Altitude With Acetazolamide at Relative Dosages NCT03424226 | Stanford University | Phase 1 |
| Completed | Effect of Acetazolamide on Acute Mountain Sickness in Lowlanders Older Than 40 Years NCT03561675 | University of Zurich | Phase 4 |
| Completed | Decompression Tables for Diving at Altitude NCT03390335 | Duke University | N/A |
| Completed | Altitude Sickness Prevention With Ibuprofen Relative to Acetazolamide and Treatment Efficacy NCT03154645 | Grant S Lipman | Phase 1 |
| Terminated | Alternative Treatments in Acute Mountain Sickness NCT03956472 | Institut de Formation et de Recherche en Médecine de Montagne | N/A |
| Completed | Altitude Sickness Prevention and Efficacy of Comparative Treatments NCT02604173 | Stanford University | Phase 3 |
| Completed | Study of Compound Danshen Dripping Pills to Treat Acute Mountain Sickness NCT03270787 | Tasly Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Completed | Inhaled Budesonide and Acute Mountain Sickness NCT02811016 | Salzburger Landeskliniken | Phase 1 |
| Completed | Study Looking at End Expiratory Pressure for Altitude Illness Decrease (SLEEP-AID) NCT01842906 | Stanford University | N/A |
| Completed | Drug Combination on Exercise Performance at High Altitude NCT01902758 | University of Montana | Phase 2 / Phase 3 |
| Unknown | Hemodynamic Changes in Altitude Adaptation NCT01698619 | Goethe University | — |
| Completed | Erythropoietin in the Prevention of Acute Mountain Sickness NCT01665781 | University of Ulsan | Phase 4 |
| Completed | Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness NCT01522326 | Massachusetts General Hospital | N/A |
| Completed | A Trial of Acetazolamide Versus Placebo in Preventing Mountain Sickness During Rapid Ascent NCT01418157 | Oxford University Clinical Research Unit, Vietnam | Phase 4 |
| Completed | Change in Peripheral Oxygen Saturation by Using Different Breathing Procedures in High Altitude NCT01468194 | University of Giessen | N/A |
| Completed | The Incidence of Subclinical High-altitude Pulmonary Oedema at High Altitude NCT01794130 | Institute of Mountain Emergency Medicine | — |
| Unknown | Sleep and Cerebral Responses to High Altitude NCT01565603 | University Hospital, Grenoble | — |
| Completed | Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness NCT01536288 | Chang Gung Memorial Hospital | Phase 2 |
| Unknown | Training in Hypoxia to Prevent Acute Mountain Sickness NCT00886912 | Heidelberg University | N/A |
| Completed | Prevention of Acute Mountain Sickness by Intermittent Hypoxia NCT00559832 | Heidelberg University | N/A |
| Completed | Acclimatization Mechanisms During Ascent to 7500m NCT00603122 | University of Zurich | N/A |
| Completed | Oxidative Stress in Hypobaric Hypoxia NCT01436383 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness NCT00664001 | Altitude Physiology Expeditions | Phase 3 |
| Completed | Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness NCT00627965 | Altitude Physiology Expeditions | Phase 4 |
| Completed | Effects of Aircraft Cabin Altitude on Passenger Comfort and Discomfort NCT00326703 | The Boeing Company | N/A |