| Not Yet Recruiting | Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal B NCT05532189 | Columbia University | N/A |
| Recruiting | Quadriceps Strengthening ACL Reconstruction NCT07015541 | Stanford University | N/A |
| Not Yet Recruiting | CT Evaluation of ACL Anatomical Reconstruction NCT06575543 | Assiut University | — |
| Recruiting | Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction Surgery NCT06486246 | Hospital Clinic of Barcelona | N/A |
| Recruiting | Preventing Injured Knees From osteoArthritis: Severity Outcomes NCT06096259 | Brigham and Women's Hospital | Phase 2 |
| Completed | Impact of Opioid Avoidance Protocol for ACL Reconstruction NCT06340932 | Matthew Varacallo | — |
| Enrolling By Invitation | Tourniquet Use in Anterior Cruciate Ligament Repair NCT05931627 | OrthoCarolina Research Institute, Inc. | N/A |
| Recruiting | Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle? NCT06235736 | University of Liverpool | — |
| Unknown | Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reco NCT06063915 | Università degli studi di Roma Foro Italico | N/A |
| Recruiting | Exploring Prolonged AMR in ACL Reconstructed Patients NCT06430775 | University Ghent | — |
| Unknown | Exparel vs. ACB With Bupivacaine for ACL Reconstruction NCT06274008 | Children's Hospital of Orange County | Phase 1 |
| Unknown | 3D Reconstruction of the Knee Based on MRI NCT05912777 | GCS Ramsay Santé pour l'Enseignement et la Recherche | N/A |
| Terminated | Knee Split Comparison After ACL Reconstruction NCT04360928 | Rush University Medical Center | N/A |
| Unknown | Psychological Factors Influencing the Patient-reported and Functional Outcome of ACL Reconstruction and Their NCT06156501 | Medical University of Vienna | N/A |
| Recruiting | Comparison of Methods in Post Operative Knee Arthroscopy Rehabilitation NCT05735236 | University of Colorado, Denver | N/A |
| Unknown | Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Car NCT05582226 | Andrews Research & Education Foundation | N/A |
| Active Not Recruiting | Readiness Outcomes Affecting Return to Sport 2.0: An Intervention Feasibility & Pilot Study NCT05338385 | Boston Children's Hospital | N/A |
| Recruiting | Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry NCT04536103 | Xiaojuan Li | — |
| Completed | Reduced Knee Flexion Strength 18 Years After ACL Reconstruction in Hamstring Group Compared to Patellar Tendon NCT05876013 | St. Olavs Hospital | — |
| Unknown | Knee vs. Ankle Training on Knee Mechanics After ACLR NCT05241795 | October 6 University | N/A |
| Recruiting | The Pediatric ALL Evaluation and Trial NCT04825587 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Active Not Recruiting | Comparison Effectiveness Analysis Between ACL Reconstruction and Rehabilitation in Peripheral and Main Capital NCT04748328 | Universitas Riau | — |
| Unknown | ACL Bone Health and Loading Study NCT04682392 | Candice Dunkin, MS, LAT, ATC | N/A |
| Unknown | Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain M NCT04721119 | Ottawa Hospital Research Institute | N/A |
| Completed | Blood Flow Restriction Training (BFR) in an Adolescent Population NCT04285879 | Connecticut Children's Medical Center | N/A |
| Withdrawn | Ultrasound for Rectus Femoris Measurement NCT04105816 | Robert Westermann | N/A |
| Unknown | Kinematic Assessment of Human Peripheral Joints by Dynamic CT NCT04732585 | Universitair Ziekenhuis Brussel | N/A |
| Unknown | The Effect of Fertilized ACL Technique on Outcomes of ACL Reconstruction in Young Adults NCT04178538 | Marshall University | N/A |
| Unknown | Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and Afte NCT04058574 | University Hospital, Caen | N/A |
| Completed | Improving ACL Reconstruction Outcomes: CBPT NCT03243162 | Vanderbilt University Medical Center | N/A |
| Completed | Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction NCT04484961 | The Methodist Hospital Research Institute | N/A |
| Completed | Safe Return to Play After ACL Reconstruction NCT04827264 | Rothman Institute Orthopaedics | — |
| Completed | Retrospective CT Imaging of BioComposite Interference Screw With BTB NCT02450292 | State University of New York at Buffalo | — |
| Unknown | ACL Reconstruction With Simple and Double Bundle Technique Using Two Different Implants for Graft Fixation NCT04550299 | Vita Care | N/A |