NCT07537738

Leukemia Stem Cell-based Assay to Predict Relapse and Survival in Patients With Acute Myeloid Leukemia

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 210 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 6 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to learn about the predict value of leukemia stem cell for acute myeloid leukemia patients with MLL-rearrangement. The main question it aims to answer is: • Could be leukemia stem cell used for relapse prediction in acute myeloid leukemia patients with MLL-rearrangement? Leukemia stem cell will be detected at the same time for participants who detected minimal residual disease using bone marrow as part of their regular medical care to answer the question.

Conditions

• Acute Myeloid Leukemia (AML)
• MLL Rearrangement

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Detection of leukemia stem cell using multiparameter flow cytometry	For AML patients with MLL rearrangement enrolled, leukemia stem cell will be detcted at diagnosis and during follow-up. A traditional Minimal residual disease was deteced as normal medical care, simultaneously, leukemia stem cell will be detcted using the sample bone marrow sample.

Timeline

• Start date: 2025-06-01
• Primary completion: 2026-04-07
• Completion: 2026-04-07
• First posted: 2026-04-17
• Last updated: 2026-04-17

Locations

1 site across 1 country: China