Trials / Not Yet Recruiting
Not Yet RecruitingNCT07535892
Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation
Pilot Trial of a Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 64 (estimated)
- Sponsor
- University of Alabama at Birmingham · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study is a single-site, pilot randomized factorial trial designed to evaluate the feasibility, acceptability, participant perceptions and preliminary effects of a multi-component behavioral intervention to support weight loss maintenance following discontinuation of GLP-1 and other anti-obesity medications. The intervention includes a standardized 10-week foundational weight loss maintenance program combined with candidate support components, including medically tailored meals, YMCA membership, and a structured mind-based program. Participants will be randomized using a 2 × 2 × 2 factorial design and followed for six months. Findings from this pilot study will inform optimization of a scalable intervention for future clinical trials.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Weight Loss Maintenance Program (Foundational) | All participants will receive a standardized 10-week foundational weight loss maintenance program designed to address three key domains: food, physical activity, and mind-based practices. This foundational program is intended to support the transition from active weight loss to long-term weight maintenance. |
| BEHAVIORAL | Mom's Meals | Medically tailored meals |
| BEHAVIORAL | YMCA Membership | YMCA membership to support physical activity |
| BEHAVIORAL | SKY Meditation Program | The SKY Meditation program to support mind-based practices |
Timeline
- Start date
- 2026-06-01
- Primary completion
- 2028-11-30
- Completion
- 2029-02-28
- First posted
- 2026-04-17
- Last updated
- 2026-04-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT07535892. Inclusion in this directory is not an endorsement.