NCT07534787

Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge

Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge (Case Series).

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the tissue biotype and bone density around dental implants in patients with narrow alveolar ridge. Ridge splitting with simultaneous implant placement covered with concentrated growth factor (CGF) membranes will be performed. Clinical and radiographic evaluation will be done using periodontal probe and CBCT. Pain will also be assessed using visual analogue scale (VAS) during follow-up period.

Detailed description

This study is a case series conducted at the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University. It aims to evaluate the tissue biotype and bone density around dental implants in adult patients with narrow alveolar ridge. Alveolar ridge resorption and soft tissue shrinkage after tooth extraction represent a major problem affecting both aesthetics and function. Therefore, preserving alveolar bone and improving soft tissue conditions are essential for successful implant placement. The use of concentrated growth factor (CGF) membranes combined with ridge splitting and simultaneous implant placement may enhance healing, reduce postoperative pain, and improve tissue biotype and bone density. All patients will undergo clinical and radiographic assessment before the procedure. Preoperative CBCT will be used for surgical planning. Tissue thickness will be measured using a periodontal probe. During surgery, ridge splitting will be performed followed by implant placement, and CGF membranes will be applied over the grafted area. Autologous bone chips will be used for augmentation. Postoperative evaluation will include assessment of tissue biotype, bone density using CBCT, and pain using visual analogue scale (VAS). Follow-up will be carried out immediately after surgery and up to 4 months postoperatively.

Conditions

• Narrow Alveolar Ridge
• CGF Concentrated Growth Factor
• Postoperative Pain
• Implant Placement

Interventions

Type	Name	Description
PROCEDURE	Ridge splitting	Patients with narrow alveolar ridge will undergo ridge splitting procedure using chisel to allow implant placement.
PROCEDURE	Dental implant placement	Intervention Description: Dental implants will be inserted simultaneously after ridge splitting in the prepared alveolar ridge.
BIOLOGICAL	Concentrated Growth Factor (CGF)	CGF membranes will be prepared from patient venous blood and placed over the grafted area to enhance healing and tissue regeneration.

Timeline

• Start date: 2026-05-01
• Primary completion: 2026-09-01
• Completion: 2026-12-30
• First posted: 2026-04-16
• Last updated: 2026-04-16

Locations

2 sites across 1 country: Egypt