NCT07534280

Herbal Tea Extract for Management of Rhinosinusitis

Efficacy of Berry Leaves & Mango Leaves Mixture in Symptomatic Treatments on Disease-related Quality of Life in Adults With Clinically Diagnosed Acute Rhinosinusitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Deraya University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The objective of this phase I controlled clinical trial is to determine the safety and efficacy of Berry leaves \& Mango leaves mixture in symptomatic treatments on disease-related quality of life in adults with clinically diagnosed acute rhinosinusitis. Ten adult subjects, 18 to 70 years old, who meet the recommended criteria for acute rhinosinusitis, will be enrolled from Minia university ENT outpatient Clinic. Subjects will be advised to add Berry leaves \& Mango leaves herbal tea mixture and followed for one month with their routine therapy (an oral decongestant, a nasal saline spray, and an antitussive agent except analgesic). Subject outcomes will be assessed by telephone interview at 0, 3, 7, 10, and 28 days. The Quality-of-life outcomes are measured on Day 3, 10 and 28 with SNOT-16, a validated evaluative instrument.

Conditions

• Rhino Sinusitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	mango leaves extract	herbal tea 3 times/day
DRUG	local steroids	local steroids once daily
OTHER	nasal saline	nasal irrigation on need
DRUG	amoxicillin clavulanates	500 mg 3 times a day

Timeline

• Start date: 2025-11-20
• Primary completion: 2026-01-10
• Completion: 2026-03-01
• First posted: 2026-04-16
• Last updated: 2026-04-16

Locations

2 sites across 1 country: Egypt